Gene · 384
ARG2: arginase 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ARG2: arginase 2. Genes, record 384. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/384
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P78540 | Arginase-2, mitochondrial | 354 | 18 | Ensembl, GeneID, HGNC |
Source UniProt
Patents70
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 37803 | P78540 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 1958 | P78540 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4527 | P78540 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1958 | P78540 | Espacenet |
| JP 2025062604 A | 2025-04-14 | 6176 | P78540 | Espacenet |
| JP 2025508840 A | 2025-04-10 | 19 | P78540 | Espacenet |
| JP 2025508467 A | 2025-03-26 | 159 | P78540 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 24629 | P78540 | Espacenet |
| US 12234288 B2 | 2025-02-25 | 51 | P78540 | Espacenet |
| US 12234474 B2 | 2025-02-25 | 3 | P78540 | Espacenet |
1 to 10 of 70
See all 70 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,130
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ARG2 papers | Newest fiscal year |
|---|---|---|---|
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 15 | 2025 |
| P01CA116087 | H. pylori-induced Inflammation and Gastric Cancer | 13 | 2025 |
| P30ES007048 | Environmental Exposures, Host Factors and Human Disease | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| R01ES010563 | Mechanisms of Manganese Neurotoxicity | 4 | 2025 |
| T32ES007028 | Training Program in Environmental Toxicology | 4 | 2025 |
| P30CA012197 | Cancer Center Support Grant | 3 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 3 | 2025 |
| P30DK036836 | Diabetes Research Center | 3 | 2025 |
| P30ES009089 | Center for Environmental Health in Northern Manhattan | 3 | 2025 |
1 to 10 of 1,130Source NIH's project files
See all 1,130 nih grantsPapers1,705
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A Flow Cytometric Method of Determining CD71+ Erythroid Cells in Neonatal Whole Blood. | Methods Mol Biol | 2026 | 42681452 | PubTator, text mining | PubMed |
| Identification of key genes related to arginine metabolism in immunoglobulin A nephropathy through the combination of scRNA-seq and bulk RNA-seq data. | Front Immunol | 2026 | 42630417 | PubTator, text mining | PubMed |
| Cleavable carbosilane dendrimers modulate the thermodynamical properties of DMPC/DPPG lipid membrane and conformation of human serum albumin. | Chem Phys Lipids | 2026 | 42580653 | PubTator, text mining | PubMed |
| Potential Drug Targets and Causal Plasma Proteins Related to Preeclampsia Identified by Mendelian Randomization. | Womens Health Rep (New Rochelle) | 2026 | 42553537 | PubTator, text mining | PubMed |
| Plasma proteome-genome integration reveals novel protein biomarkers and therapeutic targets linked to breast cancer survival. | Arch Med Sci | 2026 | 42540540 | PubTator, text mining | PubMed |
| Arginase 2 Downregulation in High-Grade Prostate Adenocarcinoma and Its Spatial Inverse Association with Tumor-Infiltrating Lymphocytes. | Asian Pac J Cancer Prev | 2026 | 42522834 | PubTator, text mining | PubMed |
| Distinct conformational dynamics of the type-2 Angiotensin II receptor bound to Angiotensin II and Angiotensin (1-7). | Sci Rep | 2026 | 42477346 | PubTator, text mining | PubMed |
| Multi-omics analysis of arginine metabolism in ovarian cancer: A prognostic signature and GTF2F2-driven stromal remodeling. | Transl Oncol | 2026 | 42442222 | PubTator, text mining | PubMed |
| Involvement of ARG2-Mediated Autophagy in Di-2-ethylhexyl Phthalate-Induced Testicular Injury. | J Biochem Mol Toxicol | 2026 | 42376685 | PubTator, text mining | PubMed |
| Bionic Copper-Piceatannol for Polyamine Depletion-Synergized Radioimmunotherapy. | ACS Appl Mater Interfaces | 2026 | 42332425 | PubTator, text mining | PubMed |
1 to 10 of 1,705
See all 1,705 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/384
GET https://conductscience.org/api/genes/v1/384/patents?page=2