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Gene · 384

ARG2: arginase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARG2: arginase 2. Genes, record 384. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/384

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Gene

Symbol
ARG2
HGNC
Name
arginase 2
HGNC
NCBI Gene ID
384
NCBI Gene
HGNC ID
HGNC:664
HGNC
Ensembl
ENSG00000081181
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P78540Arginase-2, mitochondrial35418Ensembl, GeneID, HGNC

Source UniProt

Patents70

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1437803P78540Espacenet
EP 4650780 A22025-11-191958P78540Espacenet
EP 4641202 A22025-10-294527P78540Espacenet
JP 2025517970 A2025-06-121958P78540Espacenet
JP 2025062604 A2025-04-146176P78540Espacenet
JP 2025508840 A2025-04-1019P78540Espacenet
JP 2025508467 A2025-03-26159P78540Espacenet
JP 2025032204 A2025-03-1124629P78540Espacenet
US 12234288 B22025-02-2551P78540Espacenet
US 12234474 B22025-02-253P78540Espacenet

1 to 10 of 70

See all 70 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,130

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARG2 papersNewest fiscal year
P30DK058404Molecular and Cellular Basis for Digestive Diseases152025
P01CA116087H. pylori-induced Inflammation and Gastric Cancer132025
P30ES007048Environmental Exposures, Host Factors and Human Disease82025
P30CA016672Cancer Center Support Grant72025
R01ES010563Mechanisms of Manganese Neurotoxicity42025
T32ES007028Training Program in Environmental Toxicology42025
P30CA012197Cancer Center Support Grant32025
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-202832025
P30DK036836Diabetes Research Center32025
P30ES009089Center for Environmental Health in Northern Manhattan32025

1 to 10 of 1,130Source NIH's project files

See all 1,130 nih grants

Papers1,705

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A Flow Cytometric Method of Determining CD71+ Erythroid Cells in Neonatal Whole Blood.Methods Mol Biol202642681452PubTator, text miningPubMed
Identification of key genes related to arginine metabolism in immunoglobulin A nephropathy through the combination of scRNA-seq and bulk RNA-seq data.Front Immunol202642630417PubTator, text miningPubMed
Cleavable carbosilane dendrimers modulate the thermodynamical properties of DMPC/DPPG lipid membrane and conformation of human serum albumin.Chem Phys Lipids202642580653PubTator, text miningPubMed
Potential Drug Targets and Causal Plasma Proteins Related to Preeclampsia Identified by Mendelian Randomization.Womens Health Rep (New Rochelle)202642553537PubTator, text miningPubMed
Plasma proteome-genome integration reveals novel protein biomarkers and therapeutic targets linked to breast cancer survival.Arch Med Sci202642540540PubTator, text miningPubMed
Arginase 2 Downregulation in High-Grade Prostate Adenocarcinoma and Its Spatial Inverse Association with Tumor-Infiltrating Lymphocytes.Asian Pac J Cancer Prev202642522834PubTator, text miningPubMed
Distinct conformational dynamics of the type-2 Angiotensin II receptor bound to Angiotensin II and Angiotensin (1-7).Sci Rep202642477346PubTator, text miningPubMed
Multi-omics analysis of arginine metabolism in ovarian cancer: A prognostic signature and GTF2F2-driven stromal remodeling.Transl Oncol202642442222PubTator, text miningPubMed
Involvement of ARG2-Mediated Autophagy in Di-2-ethylhexyl Phthalate-Induced Testicular Injury.J Biochem Mol Toxicol202642376685PubTator, text miningPubMed
Bionic Copper-Piceatannol for Polyamine Depletion-Synergized Radioimmunotherapy.ACS Appl Mater Interfaces202642332425PubTator, text miningPubMed

1 to 10 of 1,705

See all 1,705 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/384

GET https://conductscience.org/api/genes/v1/384/patents?page=2