Gene · 3848
KRT1: keratin 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KRT1: keratin 1. Genes, record 3848. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3848
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P04264 | Keratin, type II cytoskeletal 1 | 644 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents41
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026082974 A | 2026-05-19 | 127 | P04264 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50650 | P04264 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1012 | P04264 | Espacenet |
| WO 2025215055 A1 | 2025-10-16 | 26 | P04264 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1012 | P04264 | Espacenet |
| US 11835530 B2 | 2023-12-05 | 10 | P04264 | Espacenet |
| JP 2022546545 A | 2022-11-04 | 129 | P04264 | Espacenet |
| JP 2022141755 A | 2022-09-29 | 89 | P04264 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 42930 | P04264 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 145901 | P04264 | Espacenet |
1 to 10 of 41
See all 41 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,430
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KRT1 papers | Newest fiscal year |
|---|---|---|---|
| R01AR045192 | REGULATORS OF EPIDERMAL GENE EXPRESSION | 10 | 2025 |
| P30AR075043 | University of Michigan Skin Biology and Diseases Resource-based Center | 9 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| R01AR041836 | Function of Desmoglein 1/Pemphigus Foliaceus Antigen | 8 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| R01AR043380 | Desmoplakin Assembly and Function in Epidermis | 6 | 2025 |
| R01AR066530 | Regulators of epidermal growth and differentiation | 6 | 2025 |
| P20GM103442 | ND INBRE Health & the Environment | 5 | 2025 |
| P30AR069589 | Penn Skin Biology and Diseases Resource-based Center | 5 | 2025 |
| P30CA046934 | University of Colorado Cancer Center Support Grant | 5 | 2025 |
1 to 10 of 1,430Source NIH's project files
See all 1,430 nih grantsPapers2,853
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Pedunculoside alleviates cheilitis-like inflammation by suppressing the TLR3/TRIF/NF-κB signaling. | Int Immunopharmacol | 2026 | 42805066 | PubTator, text mining | PubMed |
| Downregulating CHI3L2 via the STAT3 Pathway: The Mechanism of Calcitriol in Suppressing Psoriatic Inflammation and Keratinocyte Hyperproliferation. | J Cell Mol Med | 2026 | 42747744 | PubTator, text mining | PubMed |
| Palmoplantar Keratoderma: A Mechanism-Based Disease Classification. | Clin Cosmet Investig Dermatol | 2026 | 42725047 | PubTator, text mining | PubMed |
| Enzymatically Hydrolyzed Eggshell Membrane Promotes Keratinocyte Differentiation Associated With PKC and Akt Signaling Pathways. | J Food Sci | 2026 | 42644214 | PubTator, text mining | PubMed |
| Multi-omics analysis reveals the effects of Jinfeng pills on the outcomes of IVF-ET in patients with poor ovarian response: a randomized controlled trial. | J Ovarian Res | 2026 | 42471705 | PubTator, text mining | PubMed |
| High-Level Secretory Expression of Recombinant Type XVII Human-like Collagen in Komagataella phaffii. | Int J Mol Sci | 2026 | 42353332 | PubTator, text mining | PubMed |
| Decoding protein signatures and protein interactions in oral potentially malignant disorders: a systematic review and network analysis. | BMC Oral Health | 2026 | 42316386 | PubTator, text mining | PubMed |
| High-level secretory production of a highly hydrophilic human-like type III collagen in Komagataella phaffii by a multicopy genomic integration strategy. | Biotechnol Lett | 2026 | 42217068 | PubTator, text mining | PubMed |
| Loss-of-function variants in EPHX3 cause nonsyndromic epidermal differentiation disorders. | Br J Dermatol | 2026 | 42178907 | PubTator, text mining | PubMed |
| Xiao Zhen Fang mitigates cutaneous toxicity by inhibiting PANoptosis: Insights from untargeted metabolomics and transcriptomics. | Fitoterapia | 2026 | 42167452 | PubTator, text mining | PubMed |
1 to 10 of 2,853
See all 2,853 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3848
GET https://conductscience.org/api/genes/v1/3848/patents?page=2