Gene · 3853
KRT6A: keratin 6A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KRT6A: keratin 6A. Genes, record 3853. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3853
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P02538 | Keratin, type II cytoskeletal 6A | 564 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents45
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 50683 | P02538 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10554 | P02538 | Espacenet |
| WO 2025215055 A1 | 2025-10-16 | 48 | P02538 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10554 | P02538 | Espacenet |
| US 12000003 B2 | 2024-06-04 | 28 | P02538 | Espacenet |
| US 11835530 B2 | 2023-12-05 | 30 | P02538 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 43021 | P02538 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 145992 | P02538 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 6033 | P02538 | Espacenet |
| KR 1020210075929 A | 2021-06-23 | 24 | P02538 | Espacenet |
1 to 10 of 45
See all 45 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,382
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KRT6A papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 10 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P20GM103442 | ND INBRE Health & the Environment | 8 | 2025 |
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 7 | 2025 |
| P30CA014236 | Cancer Center Support Grant (CCSG) | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 5 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| P30CA034196 | Cancer Center Support (CORE) Grant | 4 | 2025 |
| P01CA013106 | Targeting Transcription and Splicing in Cancer | 3 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 3 | 2025 |
1 to 10 of 1,382Source NIH's project files
See all 1,382 nih grantsPapers1,808
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
[Hepatocellular carcinoma-derived lactate-mediated histone H3K18 lactylation modifies S100A2 transcription to promote proliferation, migration, invasion and epithelial-mesenchymal transition of hepatocellular carcinoma cells]. | Nan Fang Yi Ke Da Xue Xue Bao | 2026 | 42812052 | PubTator, text mining | PubMed |
| SHC1 affects oestrogen-driven differentiation and barrier function of vaginal epithelial cells via EGFR/Ras/ERK pathway. | J Obstet Gynaecol | 2026 | 42779257 | PubTator, text mining | PubMed |
| In vitro investigation of sitagliptin on HaCaT keratinocyte migration and proteomics analysis for wound healing applications. | Eur J Pharmacol | 2026 | 42772540 | PubTator, text mining | PubMed |
| Calpeptin and protein kinase C inhibition suppress exosome-associated inflammatory signaling and epidermal dysregulation in a 3-dimensional psoriatic skin model. | J Pharmacol Exp Ther | 2026 | 42731396 | PubTator, text mining | PubMed |
| Erythrocyte fatty acid compositional patterns and cardiovascular-kidney-metabolic stage burden. | J Cardiol | 2026 | 42665016 | PubTator, text mining | PubMed |
| Spatial Transcriptomics of Micropapillary, Plasmacytoid, and Sarcomatoid Urothelial Carcinoma Reveals Distinct Molecular Landscapes. | Lab Invest | 2026 | 42641761 | PubTator, text mining | PubMed |
| Molecular Evidence for KRT6A-Associated Pachyonychia Congenita Tarda with Onset at Age 53. | Clin Cosmet Investig Dermatol | 2026 | 42577640 | PubTator, text mining | PubMed |
| Proteomic Changes of Neurodegenerative and Inflammatory Plasma Biomarkers Following Traumatic Brain Injury. | Neurotrauma Rep | 2026 | 42539370 | PubTator, text mining | PubMed |
| A multi-omics prognostic model integrating disulfidptosis-related molecular features in colorectal cancer. | Cancer Cell Int | 2026 | 42464330 | PubTator, text mining | PubMed |
| Integrated hypoxia and metabolic gene signature to predict clinical outcomes and therapeutic vulnerabilities in lung adenocarcinoma. | J Thorac Dis | 2026 | 42444878 | PubTator, text mining | PubMed |
1 to 10 of 1,808
See all 1,808 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3853
GET https://conductscience.org/api/genes/v1/3853/patents?page=2