Gene · 386653
IL31: interleukin 31
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. IL31: interleukin 31. Genes, record 386653. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/386653
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q6EBC2 | Interleukin-31 | 164 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents188
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026193162 A1 | 2026-09-17 | 4 | Q6EBC2 | Espacenet |
| WO 2026193165 A1 | 2026-09-17 | 4 | Q6EBC2 | Espacenet |
| US 12565527 B1 | 2026-03-03 | 1 | Q6EBC2 | Espacenet |
| US 12509510 B2 | 2025-12-30 | 1 | Q6EBC2 | Espacenet |
| US 12473363 B2 | 2025-11-18 | 926 | Q6EBC2 | Espacenet |
| WO 2025226834 A1 | 2025-10-30 | 1 | Q6EBC2 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10118 | Q6EBC2 | Espacenet |
| US 12448438 B2 | 2025-10-21 | 46 | Q6EBC2 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 7033 | Q6EBC2 | Espacenet |
| JP 2025138636 A | 2025-09-25 | 46 | Q6EBC2 | Espacenet |
1 to 10 of 188
See all 188 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants867
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | IL31 papers | Newest fiscal year |
|---|---|---|---|
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 7 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 5 | 2025 |
| ZIADE000721 | Molecular Genetic Studies of Somatosensation | 5 | 2025 |
| P30AR075043 | University of Michigan Skin Biology and Diseases Resource-based Center | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 4 | 2025 |
| U19AI057229 | Understanding Influenza and SARS-CoV-2 vaccine responses, in vivo and in vitro | 4 | 2025 |
| P30AG028716 | Duke Claude D. Pepper Older Americans Independence Center | 3 | 2025 |
| P30AR069589 | Penn Skin Biology and Diseases Resource-based Center | 3 | 2025 |
| P30AR075049 | Northwestern University Skin Biology and Diseases Resource-based Center | 3 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 867Source NIH's project files
See all 867 nih grantsPapers2,753
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Off-Label Uses of Nemolizumab: A Narrative Review. | J Drugs Dermatol | 2026 | 42826149 | PubTator, text mining | PubMed |
| Analytical standardization and inter-platform harmonization of immunoassay-based biomarkers in atopic dermatitis: Challenges and a roadmap for clinical laboratory implementation. | Clin Chim Acta | 2026 | 42805450 | PubTator, text mining | PubMed |
| Differential Expression of miR-146a, IL-31, and IL-33 in Osteoporosis and their Associations with Disease Severity. | Comb Chem High Throughput Screen | 2026 | 42786842 | PubTator, text mining | PubMed |
| EGR1 coordinates a nuclear IL-33-phosphorylated STAT3 transcriptional complex to promote IL31 expression in TLR1/2-activated keratinocytes. | Biochem Biophys Res Commun | 2026 | 42748574 | PubTator, text mining | PubMed |
| Herbal Extracts and Plant-Derived Bioactives in Atopic Dermatitis: Evidence, Mechanisms, Pediatric Safety, and Translational Priorities. | Food Sci Nutr | 2026 | 42732250 | PubTator, text mining | PubMed |
| Real-world effectiveness of a topical dihydroavenanthramide D formulation for chronic pruritus: A multicenter clinical study with molecular evidence of pruritogenic pathway modulation. | Narra J | 2026 | 42724128 | PubTator, text mining | PubMed |
| Understanding the Type 2 Immunity: An Evolving View Beyond Allergic Diseases. | Allergy | 2026 | 42713891 | PubTator, text mining | PubMed |
| Abrocitinib and dupilumab bridging therapy for bullous pemphigoid with insufficient response to initial corticosteroid therapy: a case report. | Front Immunol | 2026 | 42707251 | PubTator, text mining | PubMed |
| : Interleukin-31 in Atopic Dermatitis and Prurigo Nodularis: Pathophysiology, Neuroimmune Mechanisms, and Clinical Efficacy of Nemolizumab. | J Drugs Dermatol | 2026 | 42696343 | PubTator, text mining | PubMed |
| Randomized controlled study of nemolizumab in patients with chronic kidney disease-associated pruritus: NIKAIA-1. | J Am Acad Dermatol | 2026 | 42680109 | PubTator, text mining | PubMed |
1 to 10 of 2,753
See all 2,753 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/386653
GET https://conductscience.org/api/genes/v1/386653/patents?page=2