Gene · 3868
KRT16: keratin 16
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. KRT16: keratin 16. Genes, record 3868. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3868
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P08779 | Keratin, type I cytoskeletal 16 | 473 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents26
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| WO 2026222504 A1 | 2026-10-22 | 32 | P08779 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 50661 | P08779 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 42947 | P08779 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 145918 | P08779 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 6018 | P08779 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 231096 | P08779 | Espacenet |
| US 9874572 B2 | 2018-01-23 | 240 | P08779 | Espacenet |
| EP 3242136 A2 | 2017-11-08 | 240 | P08779 | Espacenet |
| US 9714950 B2 | 2017-07-25 | 240 | P08779 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 231096 | P08779 | Espacenet |
1 to 10 of 26
See all 26 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,120
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | KRT16 papers | Newest fiscal year |
|---|---|---|---|
| T32CA009110 | Training in Areas Fundamental to Cancer Research | 13 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 8 | 2025 |
| P30AR075043 | University of Michigan Skin Biology and Diseases Resource-based Center | 7 | 2025 |
| UL1TR001866 | Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success | 7 | 2025 |
| P20GM103442 | ND INBRE Health & the Environment | 6 | 2025 |
| T32AR007197 | Training Grant in Cell and Molecular Dermatology | 6 | 2025 |
| P30AR075047 | Skin Biology Resource-Based Center at UCI | 5 | 2025 |
| K08AR078251 | Mechanisms of sex discrepancy in autoimmune disease: Regulation of the female-biased VGLL3 immune pathway | 4 | 2025 |
| P30AI027763 | UCSF-Bay Area Center for AIDS Research | 4 | 2025 |
1 to 10 of 2,120Source NIH's project files
See all 2,120 nih grantsPapers3,220
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Lipoic acid synthase modulates psoriasis-like keratinocyte dysfunction in association with oxidative stress, ferroptosis-associated remodeling, and STAT3/NF-κB activation. | Naunyn Schmiedebergs Arch Pharmacol | 2026 | 42776206 | PubTator, text mining | PubMed |
| In vitro investigation of sitagliptin on HaCaT keratinocyte migration and proteomics analysis for wound healing applications. | Eur J Pharmacol | 2026 | 42772540 | PubTator, text mining | PubMed |
| Calpeptin and protein kinase C inhibition suppress exosome-associated inflammatory signaling and epidermal dysregulation in a 3-dimensional psoriatic skin model. | J Pharmacol Exp Ther | 2026 | 42731396 | PubTator, text mining | PubMed |
| Erythrocyte fatty acid compositional patterns and cardiovascular-kidney-metabolic stage burden. | J Cardiol | 2026 | 42665016 | PubTator, text mining | PubMed |
| Integrative Multi-Omics Mendelian Randomization Identifies BLMH as a Keratinocyte-Enriched Protective Candidate Gene and Potential Therapeutic Target in Psoriasis. | J Inflamm Res | 2026 | 42634679 | PubTator, text mining | PubMed |
| Direct Effects of 308-nm Excimer Light on Keratinocyte Proliferation and Differentiation in Human Organ-Cultured Skin. | Int J Mol Sci | 2026 | 42589355 | PubTator, text mining | PubMed |
| Keratin gene expression signature predicts prognosis and immunotherapy efficacy in lung adenocarcinoma. | Oncol Lett | 2026 | 42534167 | PubTator, text mining | PubMed |
| Aberrant mucin expression and keratinization distinguishing severe from mild asthma revealed by interpretable machine learning. | JCI Insight | 2026 | 42531039 | PubTator, text mining | PubMed |
| Keratin 16 puts the brakes on type I interferon signalling. | Trends Mol Med | 2026 | 42476866 | PubTator, text mining | PubMed |
| Autosomal Recessive Palmoplantar Epidermal Differentiation Disorder Caused by Homozygous Stop-Gain Variant in KRT16 Gene. | Pediatr Dermatol | 2026 | 42476612 | PubTator, text mining | PubMed |
1 to 10 of 3,220
See all 3,220 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3868
GET https://conductscience.org/api/genes/v1/3868/patents?page=2