ConductScience.org, home

Library / Genes

KRT18: keratin 18

1 protein, 138 patents, 0 drugs, 0 trials, 5,283 NIH grants and 12,740 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolKRT18HGNC
Namekeratin 18HGNC
NCBI Gene ID3875NCBI Gene
HGNC IDHGNC:6430HGNC
EnsemblENSG00000111057NCBI Gene
AliasesCK-18, CYK18, K18NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P05783Keratin, type I cytoskeletal 184300Ensembl, GeneID, HGNCUniProt

Patents 138

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-1910640P05783Espacenet
WO 2025215055 A12025-10-16135P05783Espacenet
WO 2025215055 A12025-10-16136P05783Espacenet
JP 2025517970 A2025-06-1210640P05783Espacenet
WO 2025008357 A12025-01-093P05783Espacenet
JP 2024123008 A2024-09-106737P05783Espacenet
JP 2024123008 A2024-09-106738P05783Espacenet
US 11981728 B22024-05-149P05783Espacenet
EP 4242329 A22023-09-1311P05783Espacenet
EP 4242329 A22023-09-1313P05783Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 5283

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant482,025NIH's project files
P30CA016672Cancer Center Support Grant482,025NIH's project files
P30CA046934University of Colorado Cancer Center Support Grant232,025NIH's project files
P30CA006973Regional Oncology Research Center192,025NIH's project files
P30CA030199Cancer Center Support Grant (CCSG)192,025NIH's project files
P30DK120515San Diego Digestive Diseases Research Center192,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award192,025NIH's project files
P50AA024337The Role of Nutrition in the Development/Progression of Alcohol-Induced Organ Injury162,025NIH's project files
P50CA097186The Pacific Northwest Prostate Cancer SPORE162,025NIH's project files
P20GM113226Hepatobiology and Toxicology COBRE142,025NIH's project files

Papers 12740

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42822619PubTator, text miningPubMed
42794576PubTator, text miningPubMed
42782103PubTator, text miningPubMed
42781491PubTator, text miningPubMed
42762980PubTator, text miningPubMed
42744080PubTator, text miningPubMed
42741364PubTator, text miningPubMed
42728354PubTator, text miningPubMed
42712610PubTator, text miningPubMed
42695568PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license