ConductScience.org, home

Gene · 387715

ARMS2: age-related maculopathy susceptibility 2

12 sourcesgene-search-2026-11-11-0.2.0

Download JSON
Cite this record

ConductScience Library. ARMS2: age-related maculopathy susceptibility 2. Genes, record 387715. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/387715

On this page

Gene

Symbol
ARMS2
HGNC
Name
age-related maculopathy susceptibility 2
HGNC
NCBI Gene ID
387715
NCBI Gene
HGNC ID
HGNC:32685
HGNC
Ensembl
ENSG00000254636
NCBI Gene
Aliases
ARMD8, LOC387715
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P0C7Q2Age-related maculopathy susceptibility protein 21070Ensembl, GeneID, HGNC

Source UniProt

Patents22

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19187P0C7Q2Espacenet
EP 4640849 A22025-10-292953P0C7Q2Espacenet
EP 4641201 A22025-10-2919139P0C7Q2Espacenet
JP 2025519096 A2025-06-242953P0C7Q2Espacenet
JP 2025517969 A2025-06-1219139P0C7Q2Espacenet
JP 2025062604 A2025-04-143632P0C7Q2Espacenet
WO 2024214081 A12024-10-17187P0C7Q2Espacenet
US 11564998 B22023-01-318595P0C7Q2Espacenet
US 11446398 B22022-09-203632P0C7Q2Espacenet
JP 2022524081 A2022-04-27106603P0C7Q2Espacenet

1 to 10 of 22

See all 22 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,030

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARMS2 papersNewest fiscal year
P30EY014800University of Utah Core Vision Research Grant242025
ZIAEY000489Age-Related Eye Disease Follow-up Study (AREDS) Follow-up Study242025
ZIAEY000546Mechanisms, modeling and therapies of retinal and macular neurodegeneration222025
P30EY014801Miami Center for Vision Research132025
P30EY005722Center Core Grant for Vision Research122025
P30EY001583P30 Core Grant For Vision Research102025
R01EY022445Use of Correlated Data Methods in Ophthalmology92025
P30EY014104P30 Core Grant for Vision Research72025
R01EY018213Defining Barriers to Gene Therapy62025
ZIEEY000487Medical Retina Fellowship62025

1 to 10 of 1,030Source NIH's project files

See all 1,030 nih grants

Papers1,323

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Artificial intelligence for precision therapeutics in age-related macular degeneration: current advances, challenges, and future directions.Front Artif Intell202642676384PubTator, text miningPubMed
Baseline Biomarkers Associated with Early Anatomical Response After Faricimab Loading Therapy in Treatment-Naïve Neovascular Age-Related Macular Degeneration.Biomedicines202642512063PubTator, text miningPubMed
Genome Wide Pleiotropic Analysis Reveals Shared Genetic Architecture and Pathological Basis Between Retinitis Pigmentosa and Relevant Ocular Comorbidities.Semin Ophthalmol202642359981PubTator, text miningPubMed
Genetic determinants of age-related macular degeneration in Middle Eastern populations: a systematic review.Front Genet202642180516PubTator, text miningPubMed
Genetic factors associated with response to as-needed brolucizumab treatment for exudative age-related macular degeneration.Jpn J Ophthalmol202642154379PubTator, text miningPubMed
Genetics of the retina.Handb Clin Neurol202642106178PubTator, text miningPubMed
Single-Cell Gene Expression and eQTL Analyses in the Human Retina, RPE, and Choroid in Macular Degeneration.bioRxiv202641959212PubTator, text miningPubMed
CRISPR and Beyond: Genome-Editing Strategies in Retinal Stem Cell Research.Cells202641892280PubTator, text miningPubMed
Distinct Genetic Profiles Associated With Subretinal Drusenoid Deposits and Cardiovascular Risk in Age-Related Macular Degeneration.Transl Vis Sci Technol202641879420PubTator, text miningPubMed
Trends, hotspots, and future directions of inflammation in age-related macular degeneration: A 20-year bibliometric study.Medicine (Baltimore)202641861216PubTator, text miningPubMed

1 to 10 of 1,323

See all 1,323 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/387715

GET https://conductscience.org/api/genes/v1/387715/patents?page=2