Gene · 388
RHOB: ras homolog family member B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RHOB: ras homolog family member B. Genes, record 388. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/388
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P62745 | Rho-related GTP-binding protein RhoB | 196 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents70
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 2807 | P62745 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 2372 | P62745 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4639 | P62745 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 2372 | P62745 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2807 | P62745 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 34844 | P62745 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4639 | P62745 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 34844 | P62745 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8109 | P62745 | Espacenet |
| JP 2023058610 A | 2023-04-25 | 34844 | P62745 | Espacenet |
1 to 10 of 70
See all 70 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,791
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RHOB papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA015083 | Mayo Clinic Comprehensive Cancer Center Support Grant | 6 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 5 | 2025 |
| T32ES018827 | Research Training in Environmental Toxicology | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 4 | 2025 |
| P30CA076292 | Moffitt Cancer Center Support Grant | 4 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 4 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 3 | 2025 |
1 to 10 of 1,791Source NIH's project files
See all 1,791 nih grantsPapers2,874
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Daam-, FMNL-, and mDia-family formins jointly regulate cortical actin dynamics in melanoma cells. | Cell Commun Signal | 2026 | 42827260 | PubTator, text mining | PubMed |
| PKC Inhibition by Gö6976 Promotes Osteogenic Differentiation of Dental Follicle Cells Involving Rho-Dependent Pathway Dynamics. | Biomedicines | 2026 | 42652152 | PubTator, text mining | PubMed |
| Members of the RhoA subfamily of GTPases suppress the stimulatory effect of the HPV E6 oncoprotein on the ubiquitin ligase E6AP. | Sci Rep | 2026 | 42642544 | PubTator, text mining | PubMed |
| Single-cell landscape of neutrophil activation in primary sclerosing cholangitis. | Int Immunol | 2026 | 42578956 | PubTator, text mining | PubMed |
| Bisphenol A drives the comorbidity of non-alcoholic fatty liver disease and osteoarthritis by targeting RHOB: Integrated multi-omics, single-cell analysis, and experimental validation. | Exp Gerontol | 2026 | 42476233 | PubTator, text mining | PubMed |
| Comprehensive evaluation of angiogenesis-associated genes in papillary thyroid cancer using bulk RNA and single-cell sequencing data. | Eur Arch Otorhinolaryngol | 2026 | 42472943 | PubTator, text mining | PubMed |
| tRF-17-9L5FZU3 is a novel prognostic biomarker and therapeutic target for esophageal squamous cell carcinoma: mechanisms involving RhoB suppression. | Arch Biochem Biophys | 2026 | 42425475 | PubTator, text mining | PubMed |
| SETDB1-mediated repression of RhoB promotes EMT and metastatic progression in prostate cancer. | Oncogene | 2026 | 42420589 | PubTator, text mining | PubMed |
| Phosphatidylserine and RhoB connect PI4P and PA metabolism to maintain plasma membrane identity. | J Cell Biol | 2026 | 42360433 | PubTator, text mining | PubMed |
| Integrated Bulk and Single-Cell Transcriptomic Analysis Followed by Clinical Validation Reveal Programmed Cell Death-Related Shared Molecular Signatures in OA and MDD. | Int J Mol Sci | 2026 | 42352882 | PubTator, text mining | PubMed |
1 to 10 of 2,874
See all 2,874 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/388
GET https://conductscience.org/api/genes/v1/388/patents?page=2