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Gene · 389

RHOC: ras homolog family member C

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RHOC: ras homolog family member C. Genes, record 389. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/389

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Gene

Symbol
RHOC
HGNC
Name
ras homolog family member C
HGNC
NCBI Gene ID
389
NCBI Gene
HGNC ID
HGNC:669
HGNC
Ensembl
ENSG00000155366
NCBI Gene
Aliases
ARH9, ARHC, H9, RHOH9
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P08134Rho-related GTP-binding protein RhoC1934Ensembl, GeneID, HGNC

Source UniProt

Patents140

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4801540 A12026-09-0991P08134Espacenet
EP 4650780 A22025-11-193265P08134Espacenet
EP 4641202 A22025-10-294687P08134Espacenet
JP 2025517970 A2025-06-123265P08134Espacenet
KR 1020250017231 A2025-02-044687P08134Espacenet
EP 4487869 A22025-01-08429P08134Espacenet
JP 2024123008 A2024-09-108110P08134Espacenet
JP 2024123008 A2024-09-108111P08134Espacenet
JP 2024123008 A2024-09-108112P08134Espacenet
JP 2024123008 A2024-09-108113P08134Espacenet

1 to 10 of 140

See all 140 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,543

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRHOC papersNewest fiscal year
P30CA046592University of Michigan Rogel Cancer Center Support Grant 2023-2028162025
P30CA016672Cancer Center Support Grant142025
P30CA016056Roswell Park Cancer Center Support Grant72025
P30CA086862Cancer Center Support Grant72025
P30CA010815Consolidated Basic Cancer Research Program62025
P30CA013330Cancer Center Support Grant62025
P30CA016058Cancer Center Support Grant62025
P30CA008748Cancer Center Support Grant52025
P30CA016086Cancer Center Support Grant52025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center52025

1 to 10 of 1,543Source NIH's project files

See all 1,543 nih grants

Papers2,557

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Daam-, FMNL-, and mDia-family formins jointly regulate cortical actin dynamics in melanoma cells.Cell Commun Signal202642827260PubTator, text miningPubMed
Exploring the role of statin interventions on cognitive function by Mendelian randomization study.J Alzheimers Dis Rep202642818896PubTator, text miningPubMed
miR-138-5p suppresses M2 macrophage polarization in esophageal squamous cell carcinoma via exosomes.Cell Signal202642727836PubTator, text miningPubMed
Integrative Single-Cell and Spatial Transcriptomics Identifies CRIP1+ Prehypertrophic Chondrocytes as Inflammatory Hubs and a Valuable Diagnostic Biomarker for Osteoarthritis.Mediators Inflamm202642643032PubTator, text miningPubMed
Members of the RhoA subfamily of GTPases suppress the stimulatory effect of the HPV E6 oncoprotein on the ubiquitin ligase E6AP.Sci Rep202642642544PubTator, text miningPubMed
lncRNA PCA3 plays a key role in colon cancer occurrence and development.Arch Med Sci202642540560PubTator, text miningPubMed
Characterizing the impact of plasma protein levels on human brain structure and disorders leveraging integrative multi-omics analysis.medRxiv202642528609PubTator, text miningPubMed
DHT-Induced lncRNA AC092718.4 Promotes Prostate Cancer Cell Proliferation via ceRNA Mechanism.Genes (Basel)202642194995PubTator, text miningPubMed
Sensory neurons inhibit invadopodia and metastasis via direct CGRP-RAMP1-cAMP signaling to cancer cells.bioRxiv202642079108PubTator, text miningPubMed
Single-cell sequencing reveals the functional heterogeneity of melanoma cells and their crosstalk with the tumor microenvironment.Front Genet202641993933PubTator, text miningPubMed

1 to 10 of 2,557

See all 2,557 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/389

GET https://conductscience.org/api/genes/v1/389/patents?page=2