Gene · 389
RHOC: ras homolog family member C
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. RHOC: ras homolog family member C. Genes, record 389. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/389
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P08134 | Rho-related GTP-binding protein RhoC | 193 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents140
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4801540 A1 | 2026-09-09 | 91 | P08134 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 3265 | P08134 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4687 | P08134 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 3265 | P08134 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4687 | P08134 | Espacenet |
| EP 4487869 A2 | 2025-01-08 | 429 | P08134 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8110 | P08134 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8111 | P08134 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8112 | P08134 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 8113 | P08134 | Espacenet |
1 to 10 of 140
See all 140 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,543
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | RHOC papers | Newest fiscal year |
|---|---|---|---|
| P30CA046592 | University of Michigan Rogel Cancer Center Support Grant 2023-2028 | 16 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 7 | 2025 |
| P30CA086862 | Cancer Center Support Grant | 7 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 6 | 2025 |
| P30CA013330 | Cancer Center Support Grant | 6 | 2025 |
| P30CA016058 | Cancer Center Support Grant | 6 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 5 | 2025 |
| P30CA060553 | The Robert H. Lurie Comprehensive Cancer Center | 5 | 2025 |
1 to 10 of 1,543Source NIH's project files
See all 1,543 nih grantsPapers2,557
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Daam-, FMNL-, and mDia-family formins jointly regulate cortical actin dynamics in melanoma cells. | Cell Commun Signal | 2026 | 42827260 | PubTator, text mining | PubMed |
| Exploring the role of statin interventions on cognitive function by Mendelian randomization study. | J Alzheimers Dis Rep | 2026 | 42818896 | PubTator, text mining | PubMed |
| miR-138-5p suppresses M2 macrophage polarization in esophageal squamous cell carcinoma via exosomes. | Cell Signal | 2026 | 42727836 | PubTator, text mining | PubMed |
| Integrative Single-Cell and Spatial Transcriptomics Identifies CRIP1+ Prehypertrophic Chondrocytes as Inflammatory Hubs and a Valuable Diagnostic Biomarker for Osteoarthritis. | Mediators Inflamm | 2026 | 42643032 | PubTator, text mining | PubMed |
| Members of the RhoA subfamily of GTPases suppress the stimulatory effect of the HPV E6 oncoprotein on the ubiquitin ligase E6AP. | Sci Rep | 2026 | 42642544 | PubTator, text mining | PubMed |
| lncRNA PCA3 plays a key role in colon cancer occurrence and development. | Arch Med Sci | 2026 | 42540560 | PubTator, text mining | PubMed |
| Characterizing the impact of plasma protein levels on human brain structure and disorders leveraging integrative multi-omics analysis. | medRxiv | 2026 | 42528609 | PubTator, text mining | PubMed |
| DHT-Induced lncRNA AC092718.4 Promotes Prostate Cancer Cell Proliferation via ceRNA Mechanism. | Genes (Basel) | 2026 | 42194995 | PubTator, text mining | PubMed |
| Sensory neurons inhibit invadopodia and metastasis via direct CGRP-RAMP1-cAMP signaling to cancer cells. | bioRxiv | 2026 | 42079108 | PubTator, text mining | PubMed |
| Single-cell sequencing reveals the functional heterogeneity of melanoma cells and their crosstalk with the tumor microenvironment. | Front Genet | 2026 | 41993933 | PubTator, text mining | PubMed |
1 to 10 of 2,557
See all 2,557 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/389
GET https://conductscience.org/api/genes/v1/389/patents?page=2