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Gene · 389421

LIN28B: lin-28 RNA binding posttranscriptional regulator B

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LIN28B: lin-28 RNA binding posttranscriptional regulator B. Genes, record 389421. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/389421

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Gene

Symbol
LIN28B
HGNC
Name
lin-28 RNA binding posttranscriptional regulator B
HGNC
NCBI Gene ID
389421
NCBI Gene
HGNC ID
HGNC:32207
HGNC
Ensembl
ENSG00000187772
NCBI Gene
Aliases
CSDD2, FLJ16517
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6ZN17Protein lin-28 homolog B2501Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026171881 A12026-08-2013Q6ZN17Espacenet
JP 2026004568 A2026-01-1451796Q6ZN17Espacenet
JP 2025032204 A2025-03-1130824Q6ZN17Espacenet
EP 4461818 A22024-11-1330824Q6ZN17Espacenet
JP 2023528309 A2023-07-0431Q6ZN17Espacenet
JP 2023058610 A2023-04-2530824Q6ZN17Espacenet
KR 1020230016207 A2023-02-0131Q6ZN17Espacenet
US 11446398 B22022-09-2046883Q6ZN17Espacenet
JP 2022524081 A2022-04-27149854Q6ZN17Espacenet
US 11078247 B22021-08-036224Q6ZN17Espacenet

1 to 10 of 47

See all 47 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,664

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLIN28B papersNewest fiscal year
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases92025
P30CA008748Cancer Center Support Grant82025
P30CA016520Abramson Cancer Center Support Grant72025
P30CA006927Comprehensive Cancer Center Program at Fox Chase62025
P30CA006973Regional Oncology Research Center62025
R01HD082314Deciphering the functional role of MKRN3 in puberty and reproduction62025
ZIAAI001185Roles of RNA-binding Proteins in Programming Gene Expression in Mammals62025
P30CA016058Cancer Center Support Grant52025
P30CA016672Cancer Center Support Grant52025
P30CA093373Cancer Center Support Grant P3052025

1 to 10 of 1,664Source NIH's project files

See all 1,664 nih grants

Papers2,505

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
CAFs shape the immunosuppressive microenvironment of pancreatic cancer through the Lin28b-STING Axis.Nat Commun202642693143PubTator, text miningPubMed
Precocious puberty in boys: current insights into etiology, genetic advances, and environmental factors.Front Endocrinol (Lausanne)202642534783PubTator, text miningPubMed
SARS-CoV-2 and Cancer Biology: Exploring the Mechanistic Links.Cancer Rep (Hoboken)202642499246PubTator, text miningPubMed
LIN28B is essential for human fetal B-lymphopoiesis and initiation of KMT2A::AFF1 infant leukemia.Blood202642213620PubTator, text miningPubMed
H2A.Z facilitates Sox2-nucleosome interaction by promoting DNA and histone H3 tail mobility.Nucleic Acids Res202642033231PubTator, text miningPubMed
Co-treatment of Colchicine and Rosiglitazone synergistically inhibits cytokine-driven inflammation and modulates the related hsa-miRNA26a-5p, hsa-miRNA21-5p, and STAT3 expression in non-small cell lung cancer.
Naunyn Schmiedebergs Arch Pharmacol202642012657PubTator, text miningPubMed
Heterokairic Genes and the Eco-Evo-Devo of Timing.Evol Dev202641937430PubTator, text miningPubMed
Multi-Scale Transcriptomic Sequencing Data Analysis Reveals LINC00467 is Associated with Malignant Progression in Breast Cancer: An In Silico and In Vitro Study.Oncol Res202641930179PubTator, text miningPubMed
Comparative effectiveness of 7 major human let-7-5p isoforms to modulate target gene expression in liver cells.Drug Metab Dispos202641905330PubTator, text miningPubMed
Developmental reprogramming underlies chemotherapy resistance in favorable-histology Wilms tumor.Cell Rep202641850280PubTator, text miningPubMed

1 to 10 of 2,505

See all 2,505 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/389421

GET https://conductscience.org/api/genes/v1/389421/patents?page=2