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Gene · 389692

MAFA: MAF bZIP transcription factor A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MAFA: MAF bZIP transcription factor A. Genes, record 389692. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/389692

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Gene

Symbol
MAFA
HGNC
Name
MAF bZIP transcription factor A
HGNC
NCBI Gene ID
389692
NCBI Gene
HGNC ID
HGNC:23145
HGNC
Ensembl
ENSG00000182759
NCBI Gene
Aliases
INSDM, RIPE3b1, hMafA
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q8NHW3Transcription factor MafA3531Ensembl, GeneID, HGNC

Source UniProt

Patents79

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4771163 A12026-07-086Q8NHW3Espacenet
EP 4669359 A12025-12-312Q8NHW3Espacenet
JP 2025147176 A2025-10-0615255Q8NHW3Espacenet
EP 4525933 A22025-03-264Q8NHW3Espacenet
JP 2025028160 A2025-02-2815255Q8NHW3Espacenet
KR 1020250010750 A2025-01-2115255Q8NHW3Espacenet
EP 4460562 A12024-11-134Q8NHW3Espacenet
JP 2024128028 A2024-09-2023Q8NHW3Espacenet
JP 2024128028 A2024-09-2037Q8NHW3Espacenet
JP 2024123008 A2024-09-109012Q8NHW3Espacenet

1 to 10 of 79

See all 79 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,106

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMAFA papersNewest fiscal year
P30DK020593Vanderbilt Diabetes Research Center292025
P30DK036836Diabetes Research Center212025
R01DK090570Defining the role of MafA in islet beta cells212025
P30DK020541NYR-Diabetes Research Center (NYR-DRC)142025
P30CA068485Cancer Center Support Grant122025
R01DK114233Studying the Role of the Microenvironment on Differentiation and Maturation of Beta Cells122025
P30DK020579Diabetes Research Center112025
P30DK063608Columbia Diabetes Research Center112025
P30EY008126Core Grant in Vision Research102025
P51OD011106Wisconsin National Primate Research Center Support102025

1 to 10 of 1,106Source NIH's project files

See all 1,106 nih grants

Papers1,763

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Harmine selectively enhances human beta cell identity markers and function via protein kinase A pathways.Diabetologia202642766004PubTator, text miningPubMed
MAFB in Pancreatic β-Cell Development and Dysfunction: Implications for Diabetes and Translational Applications.Biomolecules202642650744PubTator, text miningPubMed
Polystyrene Nanoplastics Drive β-Cell Dedifferentiation Through Dendritic Cell-Intrinsic MHC-I-Dependent Inflammatory Crosstalk.Adv Sci (Weinh)202642605967PubTator, text miningPubMed
Dual phenotype in a patient with adult-onset hyperinsulinism and diabetes caused by an activating MAFA variant.J Endocr Soc202642582554PubTator, text miningPubMed
MAFA: A Master Regulator of β-Cell Maturation and Function.Cells202642439674PubTator, text miningPubMed
Developmental stage-dependent cellular plasticity governs β-cell reprogramming efficiency in human fibroblasts.Biochem Biophys Res Commun202642335655PubTator, text miningPubMed
In vitro exposure to polystyrene microplastic induces oxidative stress mediated β-cell dysfunction.Toxicol In Vitro202642276532PubTator, text miningPubMed
Divergent cell-type specific hypoxia responses in human stem cell-derived and primary islets.Sci Rep202642120510PubTator, text miningPubMed
Optimal Protocol for Differentiation of Human Tonsil-Derived Mesenchymal Stem Cells into Pancreatic β-like Cells.Tissue Eng Regen Med202642018227PubTator, text miningPubMed
Unraveling the Molecular Pathways of Insulin-Producing Cells Derived From Placenta Multipotent Stem Cells via Multi-Omics Analysis.Proteomics202641919986PubTator, text miningPubMed

1 to 10 of 1,763

See all 1,763 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/389692

GET https://conductscience.org/api/genes/v1/389692/patents?page=2