Gene · 389692
MAFA: MAF bZIP transcription factor A
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MAFA: MAF bZIP transcription factor A. Genes, record 389692. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/389692
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q8NHW3 | Transcription factor MafA | 353 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents79
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4771163 A1 | 2026-07-08 | 6 | Q8NHW3 | Espacenet |
| EP 4669359 A1 | 2025-12-31 | 2 | Q8NHW3 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15255 | Q8NHW3 | Espacenet |
| EP 4525933 A2 | 2025-03-26 | 4 | Q8NHW3 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15255 | Q8NHW3 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 15255 | Q8NHW3 | Espacenet |
| EP 4460562 A1 | 2024-11-13 | 4 | Q8NHW3 | Espacenet |
| JP 2024128028 A | 2024-09-20 | 23 | Q8NHW3 | Espacenet |
| JP 2024128028 A | 2024-09-20 | 37 | Q8NHW3 | Espacenet |
| JP 2024123008 A | 2024-09-10 | 9012 | Q8NHW3 | Espacenet |
1 to 10 of 79
See all 79 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,106
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MAFA papers | Newest fiscal year |
|---|---|---|---|
| P30DK020593 | Vanderbilt Diabetes Research Center | 29 | 2025 |
| P30DK036836 | Diabetes Research Center | 21 | 2025 |
| R01DK090570 | Defining the role of MafA in islet beta cells | 21 | 2025 |
| P30DK020541 | NYR-Diabetes Research Center (NYR-DRC) | 14 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 12 | 2025 |
| R01DK114233 | Studying the Role of the Microenvironment on Differentiation and Maturation of Beta Cells | 12 | 2025 |
| P30DK020579 | Diabetes Research Center | 11 | 2025 |
| P30DK063608 | Columbia Diabetes Research Center | 11 | 2025 |
| P30EY008126 | Core Grant in Vision Research | 10 | 2025 |
| P51OD011106 | Wisconsin National Primate Research Center Support | 10 | 2025 |
1 to 10 of 1,106Source NIH's project files
See all 1,106 nih grantsPapers1,763
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Harmine selectively enhances human beta cell identity markers and function via protein kinase A pathways. | Diabetologia | 2026 | 42766004 | PubTator, text mining | PubMed |
| MAFB in Pancreatic β-Cell Development and Dysfunction: Implications for Diabetes and Translational Applications. | Biomolecules | 2026 | 42650744 | PubTator, text mining | PubMed |
| Polystyrene Nanoplastics Drive β-Cell Dedifferentiation Through Dendritic Cell-Intrinsic MHC-I-Dependent Inflammatory Crosstalk. | Adv Sci (Weinh) | 2026 | 42605967 | PubTator, text mining | PubMed |
| Dual phenotype in a patient with adult-onset hyperinsulinism and diabetes caused by an activating MAFA variant. | J Endocr Soc | 2026 | 42582554 | PubTator, text mining | PubMed |
| MAFA: A Master Regulator of β-Cell Maturation and Function. | Cells | 2026 | 42439674 | PubTator, text mining | PubMed |
| Developmental stage-dependent cellular plasticity governs β-cell reprogramming efficiency in human fibroblasts. | Biochem Biophys Res Commun | 2026 | 42335655 | PubTator, text mining | PubMed |
| In vitro exposure to polystyrene microplastic induces oxidative stress mediated β-cell dysfunction. | Toxicol In Vitro | 2026 | 42276532 | PubTator, text mining | PubMed |
| Divergent cell-type specific hypoxia responses in human stem cell-derived and primary islets. | Sci Rep | 2026 | 42120510 | PubTator, text mining | PubMed |
| Optimal Protocol for Differentiation of Human Tonsil-Derived Mesenchymal Stem Cells into Pancreatic β-like Cells. | Tissue Eng Regen Med | 2026 | 42018227 | PubTator, text mining | PubMed |
| Unraveling the Molecular Pathways of Insulin-Producing Cells Derived From Placenta Multipotent Stem Cells via Multi-Omics Analysis. | Proteomics | 2026 | 41919986 | PubTator, text mining | PubMed |
1 to 10 of 1,763
See all 1,763 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/389692
GET https://conductscience.org/api/genes/v1/389692/patents?page=2