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Gene · 39

ACAT2: acetyl-CoA acetyltransferase 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ACAT2: acetyl-CoA acetyltransferase 2. Genes, record 39. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/39

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Gene

Symbol
ACAT2
HGNC
Name
acetyl-CoA acetyltransferase 2
HGNC
NCBI Gene ID
39
NCBI Gene
HGNC ID
HGNC:94
HGNC
Ensembl
ENSG00000120437
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q9BWD1Acetyl-CoA acetyltransferase, cytosolic3974Ensembl, GeneID, HGNC

Source UniProt

Patents88

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1436001Q9BWD1Espacenet
EP 4650780 A22025-11-198158Q9BWD1Espacenet
EP 4641202 A22025-10-295377Q9BWD1Espacenet
JP 2025517970 A2025-06-128158Q9BWD1Espacenet
JP 2025062604 A2025-04-141239Q9BWD1Espacenet
KR 1020250017231 A2025-02-045377Q9BWD1Espacenet
US 11708610 B22023-07-25928Q9BWD1Espacenet
US 11708610 B22023-07-25929Q9BWD1Espacenet
JP 2023510565 A2023-03-14283Q9BWD1Espacenet
US 11446398 B22022-09-201239Q9BWD1Espacenet

1 to 10 of 88

See all 88 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants721

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleACAT2 papersNewest fiscal year
P30CA008748Cancer Center Support Grant42025
P30CA046934University of Colorado Cancer Center Support Grant42025
P30CA072720Cancer Center Support Grant32025
R01CA140515Signaling importance of ‘functionless’ lyso-PAF, an inactive form of platelet activating factor, in melanoma with mutant Nras32025
P30CA016056Roswell Park Cancer Center Support Grant22025
P30CA060553The Robert H. Lurie Comprehensive Cancer Center22025
P30CA076292Moffitt Cancer Center Support Grant22025
P30CA125123Baylor College of Medicine Cancer Center - Cancer Center Support Grant22025
P30DK056338Texas Medical Center Digestive Diseases Center22025
P30ES010126UNC Center for Environmental Health and Susceptibility22025

1 to 10 of 721Source NIH's project files

See all 721 nih grants

Papers1,100

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Increased LDL-C reduction with ezetimibe in ketogenic diet-induced hypercholesterolemia.Lipids Health Dis202642661192PubTator, text miningPubMed
SIRT2 deacylase modulators control B cell metabolic reprogramming in EBV infection and mitogenic activation.Proc Natl Acad Sci U S A202642636358PubTator, text miningPubMed
Blood-Based Epigenetic Aging Signatures in D3GHR Carriers: An Exploratory Pilot Study of Metabolic Adaptation and Aging-Related Pathways.Int J Mol Sci202642352906PubTator, text miningPubMed
A chemoproteomic atlas of the human purine interactome for regioselective ligand discovery.Nat Commun202642248851PubTator, text miningPubMed
Systems pharmacology approaches to modeling immune training and tolerance.Curr Opin Pharmacol202642127728PubTator, text miningPubMed
Proteomic Profiling Reveals the Synergistic Effects of Astaxanthin and Melatonin on the Inhibition of Cryoinjuries in Ram Sperm.J Proteome Res202642101457PubTator, text miningPubMed
Cell type-specific alterations in fatty acid metabolism in neuronal subpopulations of schizophrenia and construction of a diagnostic model.Front Psychiatry202642094829PubTator, text miningPubMed
The Crimean-Congo haemorrhagic fever virus hijacks the liver lipid metabolic pathway for virion production.Emerg Microbes Infect202641911362PubTator, text miningPubMed
The histone acylation network: emerging therapeutic targets for remodeling the epigenetic landscape in pancreatic ductal adenocarcinoma.Cell Oncol (Dordr)202641874858PubTator, text miningPubMed
NUAK1 silencing enhances radiotherapy-induced ferroptosis in locally advanced rectal cancer by impairing Nrf2-driven transcription of GPX4.Cell Oncol (Dordr)202641848996PubTator, text miningPubMed

1 to 10 of 1,100

See all 1,100 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/39

GET https://conductscience.org/api/genes/v1/39/patents?page=2