Gene · 3903
LAIR1: leukocyte associated immunoglobulin like receptor 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LAIR1: leukocyte associated immunoglobulin like receptor 1. Genes, record 3903. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3903
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q6GTX8 | Leukocyte-associated immunoglobulin-like receptor 1 | 287 | 5 | Ensembl, GeneID, HGNC |
Source UniProt
Patents23
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4806462 A2 | 2026-09-16 | 39 | Q6GTX8 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10849 | Q6GTX8 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 11205 | Q6GTX8 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 621 | Q6GTX8 | Espacenet |
| EP 4641203 A2 | 2025-10-29 | 373 | Q6GTX8 | Espacenet |
| JP 2025532639 A | 2025-10-01 | 29 | Q6GTX8 | Espacenet |
| JP 2025517967 A | 2025-06-12 | 373 | Q6GTX8 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 11205 | Q6GTX8 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10849 | Q6GTX8 | Espacenet |
| KR 1020250080868 A | 2025-06-05 | 29 | Q6GTX8 | Espacenet |
1 to 10 of 23
See all 23 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants680
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LAIR1 papers | Newest fiscal year |
|---|---|---|---|
| ZIAAI000825 | Role of B Lymphocytes In HIV Infection And Pathogenesis | 6 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P01AI039671 | Costimulatory Mechanisms of Autoimmunity | 4 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 4 | 2025 |
| P50CA121974 | Yale SPORE in Skin Cancer | 4 | 2025 |
| U19AI089992 | Immune signatures of vaccine responses in vulnerable populations | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA016056 | Roswell Park Cancer Center Support Grant | 3 | 2025 |
| P30CA091842 | Cancer Center Support Grant | 3 | 2025 |
| P51OD011132 | Emory National Primate Research Center | 3 | 2025 |
1 to 10 of 680Source NIH's project files
See all 680 nih grantsPapers1,353
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell-CD155-TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression. | Barrier Immun | 2026 | 42819567 | PubTator, text mining | PubMed |
| Type I collagen matrix signaling in cancer: receptor sensing and mechanotransduction. | Cell Signal | 2026 | 42660397 | PubTator, text mining | PubMed |
| A dual pronged approach to cancer immune exclusion: tumor-derived LAIR-1 simultaneously drives fibrosis and blocks immune recruitment in glioma. | Res Sq | 2026 | 42620371 | PubTator, text mining | PubMed |
| Machine learning-driven development of a novel unfolded protein response-related gene signature for predicting lung adenocarcinoma patient prognosis. | BMC Cancer | 2026 | 42401850 | PubTator, text mining | PubMed |
Decoding chromatin regulator-LAIR1+ M2 like macrophage patterns in atherosclerosis and clinical outcomes of Lung adenocarcinoma patients: evidence from artificial intelligence-driven multi omics and in vitro validation. | Clin Exp Med | 2026 | 42319401 | PubTator, text mining | PubMed |
| Unveiling LAIR1: a prognostic biomarker associated with gastric cancer progression and metastasis. | Transl Cancer Res | 2026 | 42305472 | PubTator, text mining | PubMed |
| Development and validation of an m6A and autophagy related lncRNAs signature for predicting survival and modulating the immune microenvironment in esophageal squamous cell carcinoma. | Front Immunol | 2026 | 42292425 | PubTator, text mining | PubMed |
| Serum proteomic atlas reveals distinct molecular signatures of lupus nephritis activity, chronicity, and treatment response. | bioRxiv | 2026 | 42182176 | PubTator, text mining | PubMed |
| Multimodal transcriptomics reveal myCAF-derived collagen signaling associated with impaired NK-cell cytotoxicity and immune exclusion in pancreatic cancer. | J Transl Med | 2026 | 42174623 | PubTator, text mining | PubMed |
| A multimodal atlas for immunotherapeutic targeting of AML surface heterogeneity. | iScience | 2026 | 41959675 | PubTator, text mining | PubMed |
1 to 10 of 1,353
See all 1,353 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3903
GET https://conductscience.org/api/genes/v1/3903/patents?page=2