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Gene · 3903

LAIR1: leukocyte associated immunoglobulin like receptor 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LAIR1: leukocyte associated immunoglobulin like receptor 1. Genes, record 3903. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3903

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Gene

Symbol
LAIR1
HGNC
Name
leukocyte associated immunoglobulin like receptor 1
HGNC
NCBI Gene ID
3903
NCBI Gene
HGNC ID
HGNC:6477
HGNC
Ensembl
ENSG00000167613
NCBI Gene
Aliases
CD305, LAIR-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q6GTX8Leukocyte-associated immunoglobulin-like receptor 12875Ensembl, GeneID, HGNC

Source UniProt

Patents23

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4806462 A22026-09-1639Q6GTX8Espacenet
EP 4650780 A22025-11-1910849Q6GTX8Espacenet
EP 4641201 A22025-10-2911205Q6GTX8Espacenet
EP 4641202 A22025-10-29621Q6GTX8Espacenet
EP 4641203 A22025-10-29373Q6GTX8Espacenet
JP 2025532639 A2025-10-0129Q6GTX8Espacenet
JP 2025517967 A2025-06-12373Q6GTX8Espacenet
JP 2025517969 A2025-06-1211205Q6GTX8Espacenet
JP 2025517970 A2025-06-1210849Q6GTX8Espacenet
KR 1020250080868 A2025-06-0529Q6GTX8Espacenet

1 to 10 of 23

See all 23 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants680

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLAIR1 papersNewest fiscal year
ZIAAI000825Role of B Lymphocytes In HIV Infection And Pathogenesis62025
P30CA016672Cancer Center Support Grant52025
P01AI039671Costimulatory Mechanisms of Autoimmunity42025
P30CA068485Cancer Center Support Grant42025
P50CA121974Yale SPORE in Skin Cancer42025
U19AI089992Immune signatures of vaccine responses in vulnerable populations42025
P30CA008748Cancer Center Support Grant32025
P30CA016056Roswell Park Cancer Center Support Grant32025
P30CA091842Cancer Center Support Grant32025
P51OD011132Emory National Primate Research Center32025

1 to 10 of 680Source NIH's project files

See all 680 nih grants

Papers1,353

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Integrative Omics Analysis Reveals a CD206+ Macrophage/Dendritic Cell-CD155-TIGIT+ Regulatory T Cell Axis as a Protective Immune Checkpoint Pathway in Atherosclerosis Progression.Barrier Immun202642819567PubTator, text miningPubMed
Type I collagen matrix signaling in cancer: receptor sensing and mechanotransduction.Cell Signal202642660397PubTator, text miningPubMed
A dual pronged approach to cancer immune exclusion: tumor-derived LAIR-1 simultaneously drives fibrosis and blocks immune recruitment in glioma.Res Sq202642620371PubTator, text miningPubMed
Machine learning-driven development of a novel unfolded protein response-related gene signature for predicting lung adenocarcinoma patient prognosis.BMC Cancer202642401850PubTator, text miningPubMed
Decoding chromatin regulator-LAIR1+ M2 like macrophage patterns in atherosclerosis and clinical outcomes of Lung adenocarcinoma patients: evidence from artificial intelligence-driven multi omics and in vitro validation.
Clin Exp Med202642319401PubTator, text miningPubMed
Unveiling LAIR1: a prognostic biomarker associated with gastric cancer progression and metastasis.Transl Cancer Res202642305472PubTator, text miningPubMed
Development and validation of an m6A and autophagy related lncRNAs signature for predicting survival and modulating the immune microenvironment in esophageal squamous cell carcinoma.Front Immunol202642292425PubTator, text miningPubMed
Serum proteomic atlas reveals distinct molecular signatures of lupus nephritis activity, chronicity, and treatment response.bioRxiv202642182176PubTator, text miningPubMed
Multimodal transcriptomics reveal myCAF-derived collagen signaling associated with impaired NK-cell cytotoxicity and immune exclusion in pancreatic cancer.J Transl Med202642174623PubTator, text miningPubMed
A multimodal atlas for immunotherapeutic targeting of AML surface heterogeneity.iScience202641959675PubTator, text miningPubMed

1 to 10 of 1,353

See all 1,353 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3903

GET https://conductscience.org/api/genes/v1/3903/patents?page=2