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Gene · 3908

LAMA2: laminin subunit alpha 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LAMA2: laminin subunit alpha 2. Genes, record 3908. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3908

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Gene

Symbol
LAMA2
HGNC
Name
laminin subunit alpha 2
HGNC
NCBI Gene ID
3908
NCBI Gene
HGNC ID
HGNC:6482
HGNC
Ensembl
ENSG00000196569
NCBI Gene
Aliases
LAMM, MDC1A
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P24043Laminin subunit alpha-23,1222Ensembl, GeneID, HGNC

Source UniProt

Patents47

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1451084P24043Espacenet
EP 4650780 A22025-11-1913034P24043Espacenet
EP 4641201 A22025-10-2914659P24043Espacenet
EP 4641203 A22025-10-29450P24043Espacenet
JP 2025147176 A2025-10-067643P24043Espacenet
JP 2025529142 A2025-09-046850P24043Espacenet
US 12371689 B22025-07-296850P24043Espacenet
JP 2025517967 A2025-06-12450P24043Espacenet
JP 2025517969 A2025-06-1214659P24043Espacenet
JP 2025517970 A2025-06-1213034P24043Espacenet

1 to 10 of 47

See all 47 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
OCRIPLASMINCHEMBL2095222Laminin hydrolytic enzymeHYDROLYTIC ENZYME

Source ChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02747030OCRIPLASMINPHASE1ClinicalTrials.gov
NCT02681809OCRIPLASMINPHASE22020-12-16ClinicalTrials.gov
NCT01429441OCRIPLASMINPHASE32016-01-11ClinicalTrials.gov
NCT00996684OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00798317OCRIPLASMINPHASE32013-01-30ClinicalTrials.gov
NCT00781859OCRIPLASMINPHASE32013-01-28ClinicalTrials.gov
NCT00428129OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00412451OCRIPLASMINPHASE22013-09-13ClinicalTrials.gov
NCT00123305OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00123266OCRIPLASMINPHASE2ClinicalTrials.gov

NIH grants1,398

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLAMA2 papersNewest fiscal year
ZIANS003129Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies252025
P50NS053672Muscular Dystrophy Specialized Research Center42025
UL1TR001863Yale Clinical and Translational Science Award42025
P30CA008748Cancer Center Support Grant32025
P30CA016058Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
I01BX003824Advanced conformational changes in NOTCH3 and cerebrovascular disease severity22025
K12CA090628Paul Calabresi Program in Clinical/Translational Research at Mayo Clinic22025
P01HL141084Multiscale Systems to Elucidate Susceptibility and Cardioprotective Mechanisms in Cardio-oncology22025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 522025

1 to 10 of 1,398Source NIH's project files

See all 1,398 nih grants

Papers2,255

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Conserved neuronal-like and secretory programs define the spatial architecture of gastroenteropancreatic neuroendocrine tumors.J Clin Invest202642678737PubTator, text miningPubMed
Nanofibrous Matrices Modulating Glioma Cell Migration and Proliferation and the Exploration of Their Molecular Mechanism.ACS Appl Bio Mater202642606053PubTator, text miningPubMed
Triple-AAV intein-mediated gene therapy ameliorates dystrophic phenotype in MDC1A mice.Mol Ther202642528140PubTator, text miningPubMed
Integrative multi-omics analysis identifies stellate cell-derived complement component 7 as a predictor of fibrosis and liver-related events in MASLD.JHEP Rep202642486350PubTator, text miningPubMed
Cause of a fatal multi-organ fat embolism syndrome in a patient with LAMA2-associated congenital muscular dystrophy.Forensic Sci Med Pathol202642390674PubTator, text miningPubMed
Polymerizing laminins: Assembly, functions and disorders.Matrix Biol202642349693PubTator, text miningPubMed
Comments on the "Unexplained multiorgan fat embolism syndrome in a 10-year-old child with LAMA2-related congenital muscular dystrophy", and on the subsequent correspondence.Forensic Sci Med Pathol202642319696PubTator, text miningPubMed
Gene-Environment Interaction Loci Associated with Refractive Error: SCAMPI Analysis.Ophthalmol Sci202642293346PubTator, text miningPubMed
The Effect of Trunk Brace Use on Motor and Pulmonary Functions in a Patient with LAMA2-Related Congenital Muscular Dystrophy: A Case Report.Stud Health Technol Inform202642290440PubTator, text miningPubMed
The Proliferation and Adipogenic/Fibrogenic Fate Commitment of FAPs via an Autocrine LAMA2/ITGβ1-FAK Pathway.J Agric Food Chem202642267524PubTator, text miningPubMed

1 to 10 of 2,255

See all 2,255 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3908

GET https://conductscience.org/api/genes/v1/3908/patents?page=2