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Gene · 391

RHOG: ras homolog family member G

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. RHOG: ras homolog family member G. Genes, record 391. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/391

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Gene

Symbol
RHOG
HGNC
Name
ras homolog family member G
HGNC
NCBI Gene ID
391
NCBI Gene
HGNC ID
HGNC:672
HGNC
Ensembl
ENSG00000177105
NCBI Gene
Aliases
ARHG, MGC125835, MGC125836
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P84095Rho-related GTP-binding protein RhoG1916Ensembl, GeneID, HGNC

Source UniProt

Patents28

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4801540 A12026-09-0979P84095Espacenet
EP 4650780 A22025-11-196438P84095Espacenet
JP 2025517970 A2025-06-126438P84095Espacenet
US 11884978 B22024-01-30709P84095Espacenet
US 11446398 B22022-09-2071822P84095Espacenet
US 11446398 B22022-09-2071823P84095Espacenet
US 11446398 B22022-09-2071824P84095Espacenet
US 11446398 B22022-09-2071825P84095Espacenet
JP 2022524081 A2022-04-27174793P84095Espacenet
JP 2022524081 A2022-04-27174794P84095Espacenet

1 to 10 of 28

See all 28 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,420

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleRHOG papersNewest fiscal year
T32CA009109Cancer Research Training Program: From Molecular Mechanisms to Therapeutic Strategies62025
P30CA013330Cancer Center Support Grant42025
P30CA016086Cancer Center Support Grant42025
P30CA008748Cancer Center Support Grant32025
P30CA016672Cancer Center Support Grant32025
P30CA046934University of Colorado Cancer Center Support Grant32025
P51OD011092Support for National Primate Research Center32025
R35GM122596Dissecting signaling in vivo via precise control and visualization of protein activity32025
R35GM136226Multiplex Imaging of Signaling Pathways in Cell Motility32025
T32ES018827Research Training in Environmental Toxicology32025

1 to 10 of 1,420Source NIH's project files

See all 1,420 nih grants

Papers1,903

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
PKC Inhibition by Gö6976 Promotes Osteogenic Differentiation of Dental Follicle Cells Involving Rho-Dependent Pathway Dynamics.Biomedicines202642652152PubTator, text miningPubMed
α 1A-Adrenergic receptor (ADRA1A) signaling signatures as prognostic biomarkers in liver hepatocellular carcinoma: a bioinformatic analysis.In Silico Pharmacol202642542688PubTator, text miningPubMed
SGEF coordinates epithelial morphogenesis by regulating junction stability, collective migration, and extracellular matrix remodeling.bioRxiv202642538976PubTator, text miningPubMed
A Rho GTPase-related gene signature predicts prognosis and reveals an immunosuppressive microenvironment in lung adenocarcinoma: an integrated analysis of bulk and single-cell RNA sequencing data.Sci Rep202642469385PubTator, text miningPubMed
Persistence without turnover: the RhoG G12E mutant highlights the role of nucleotide cycling in RhoG signaling.Biochem J202642384407PubTator, text miningPubMed
Supercharging the metabolic engine: mitochondrial engineering strategies for CAR-T persistence in solid tumors.Front Immunol202642183245PubTator, text miningPubMed
RhoG, Rac1 and Cdc42 cooperation in cell protrusion revealed by multiplexed optogenetics and biosensor imaging.bioRxiv202642182105PubTator, text miningPubMed
Recent advances in CDC42 subfamily inhibition and therapeutic potential.Trends Pharmacol Sci202642168045PubTator, text miningPubMed
The RhoG-Binding Domain of ELMO1 Rescues the PTENopathy-like Phenotype in Oligodendroglial FBD-102b Cells.Int J Mol Sci202642074101PubTator, text miningPubMed
TBXA2R activates ERMs to drive motility, invasion, and metastatic colonization of TNBC cells.Life Sci Alliance202641844278PubTator, text miningPubMed

1 to 10 of 1,903

See all 1,903 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/391

GET https://conductscience.org/api/genes/v1/391/patents?page=2