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Gene · 3910

LAMA4: laminin subunit alpha 4

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LAMA4: laminin subunit alpha 4. Genes, record 3910. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3910

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Gene

Symbol
LAMA4
HGNC
Name
laminin subunit alpha 4
HGNC
NCBI Gene ID
3910
NCBI Gene
HGNC ID
HGNC:6484
HGNC
Ensembl
ENSG00000112769
NCBI Gene
Aliases
CMD1JJ, LAMA3, LAMA4*-1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q16363Laminin subunit alpha-41,8230Ensembl, GeneID, HGNC

Source UniProt

Patents48

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-19773Q16363Espacenet
EP 4641201 A22025-10-29548Q16363Espacenet
JP 2025147176 A2025-10-067660Q16363Espacenet
JP 2025517969 A2025-06-12548Q16363Espacenet
JP 2025517970 A2025-06-12773Q16363Espacenet
JP 2025032204 A2025-03-1130677Q16363Espacenet
JP 2025028160 A2025-02-287660Q16363Espacenet
JP 2025024198 A2025-02-1913306Q16363Espacenet
KR 1020250010750 A2025-01-217660Q16363Espacenet
EP 4461818 A22024-11-1330677Q16363Espacenet

1 to 10 of 48

See all 48 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
OCRIPLASMINCHEMBL2095222Laminin hydrolytic enzymeHYDROLYTIC ENZYME

Source ChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02747030OCRIPLASMINPHASE1ClinicalTrials.gov
NCT02681809OCRIPLASMINPHASE22020-12-16ClinicalTrials.gov
NCT01429441OCRIPLASMINPHASE32016-01-11ClinicalTrials.gov
NCT00996684OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00798317OCRIPLASMINPHASE32013-01-30ClinicalTrials.gov
NCT00781859OCRIPLASMINPHASE32013-01-28ClinicalTrials.gov
NCT00428129OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00412451OCRIPLASMINPHASE22013-09-13ClinicalTrials.gov
NCT00123305OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00123266OCRIPLASMINPHASE2ClinicalTrials.gov

NIH grants902

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLAMA4 papersNewest fiscal year
P30CA016042Cancer Center Support Grant52025
P30DK020595Diabetes Research and Training Center52025
P30CA016672Cancer Center Support Grant42025
P30CA008748Cancer Center Support Grant32025
R01EY013431Mechanisms of epithelial alterations in diabetic cornea32025
U54GM104940Louisiana Clinical and Translational Science Center32025
UL1TR001863Yale Clinical and Translational Science Award32025
I01BX003690Tunable Assembly of Regulatory Immune Signals to Promote Myelin-specific Tolerance22025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 522025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025

1 to 10 of 902Source NIH's project files

See all 902 nih grants

Papers1,288

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Protein Expression Dynamics in Breast Cancer Cells Exposed to Nano-Encapsulated Tarin, the Taro Lectin.Pharmaceutics202642797298PubTator, text miningPubMed
Lymph node extracellular matrix skews the immune function of human fibroblastic reticular cells.iScience202642780986PubTator, text miningPubMed
Structural Basis for MCAM Mediated Inhibition of Laminin Dependent Cell Migration.bioRxiv202642779840PubTator, text miningPubMed
Laminin β4 is required for the development of human peripheral sensory neurons.Development202642690250PubTator, text miningPubMed
CD39+CD103+CD8+ T cells enhance neoadjuvant chemoimmunotherapy efficacy in head and neck squamous cell carcinoma.Br J Cancer202642618591PubTator, text miningPubMed
Nanofibrous Matrices Modulating Glioma Cell Migration and Proliferation and the Exploration of Their Molecular Mechanism.ACS Appl Bio Mater202642606053PubTator, text miningPubMed
Decoding the Complexity of Hepatocellular Carcinoma: Clinical Challenges and Targeting HuR as a Novel Therapeutic Strategy.Livers202642583674PubTator, text miningPubMed
Plectin 1d Isoform as a Potential Regulator of Metastatic Progression in Papillary Thyroid Carcinoma.Int J Mol Sci202642511682PubTator, text miningPubMed
Co-Assembling 3D In Vitro Model to Recreate the Colorectal Tumor Microenvironment.Adv Healthc Mater202642216422PubTator, text miningPubMed
A transcriptionally distinct population of human adipocytes with end-of-trajectory signature (hEOS) emerges during obesity to drive maladaptive inflammation.Pharmacol Res202642107509PubTator, text miningPubMed

1 to 10 of 1,288

See all 1,288 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3910

GET https://conductscience.org/api/genes/v1/3910/patents?page=2