Gene · 3910
LAMA4: laminin subunit alpha 4
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LAMA4: laminin subunit alpha 4. Genes, record 3910. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3910
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q16363 | Laminin subunit alpha-4 | 1,823 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents48
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 773 | Q16363 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 548 | Q16363 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 7660 | Q16363 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 548 | Q16363 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 773 | Q16363 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 30677 | Q16363 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 7660 | Q16363 | Espacenet |
| JP 2025024198 A | 2025-02-19 | 13306 | Q16363 | Espacenet |
| KR 1020250010750 A | 2025-01-21 | 7660 | Q16363 | Espacenet |
| EP 4461818 A2 | 2024-11-13 | 30677 | Q16363 | Espacenet |
1 to 10 of 48
See all 48 patentsDrugs1
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
| Drug | ChEMBL ID | Mechanism | Action |
|---|---|---|---|
| OCRIPLASMIN | CHEMBL2095222 | Laminin hydrolytic enzyme | HYDROLYTIC ENZYME |
Source ChEMBL
Trials10
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
| Trial | Drug | Phase | Results first posted | Source |
|---|---|---|---|---|
| NCT02747030 | OCRIPLASMIN | PHASE1 | ClinicalTrials.gov | |
| NCT02681809 | OCRIPLASMIN | PHASE2 | 2020-12-16 | ClinicalTrials.gov |
| NCT01429441 | OCRIPLASMIN | PHASE3 | 2016-01-11 | ClinicalTrials.gov |
| NCT00996684 | OCRIPLASMIN | PHASE2 | ClinicalTrials.gov | |
| NCT00798317 | OCRIPLASMIN | PHASE3 | 2013-01-30 | ClinicalTrials.gov |
| NCT00781859 | OCRIPLASMIN | PHASE3 | 2013-01-28 | ClinicalTrials.gov |
| NCT00428129 | OCRIPLASMIN | PHASE2 | ClinicalTrials.gov | |
| NCT00412451 | OCRIPLASMIN | PHASE2 | 2013-09-13 | ClinicalTrials.gov |
| NCT00123305 | OCRIPLASMIN | PHASE2 | ClinicalTrials.gov | |
| NCT00123266 | OCRIPLASMIN | PHASE2 | ClinicalTrials.gov |
NIH grants902
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LAMA4 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016042 | Cancer Center Support Grant | 5 | 2025 |
| P30DK020595 | Diabetes Research and Training Center | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 4 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| R01EY013431 | Mechanisms of epithelial alterations in diabetic cornea | 3 | 2025 |
| U54GM104940 | Louisiana Clinical and Translational Science Center | 3 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 3 | 2025 |
| I01BX003690 | Tunable Assembly of Regulatory Immune Signals to Promote Myelin-specific Tolerance | 2 | 2025 |
| P20GM103418 | Kansas IDeA Network of Biomedical Research Excellence 5 | 2 | 2025 |
| P30CA006927 | Comprehensive Cancer Center Program at Fox Chase | 2 | 2025 |
1 to 10 of 902Source NIH's project files
See all 902 nih grantsPapers1,288
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Protein Expression Dynamics in Breast Cancer Cells Exposed to Nano-Encapsulated Tarin, the Taro Lectin. | Pharmaceutics | 2026 | 42797298 | PubTator, text mining | PubMed |
| Lymph node extracellular matrix skews the immune function of human fibroblastic reticular cells. | iScience | 2026 | 42780986 | PubTator, text mining | PubMed |
| Structural Basis for MCAM Mediated Inhibition of Laminin Dependent Cell Migration. | bioRxiv | 2026 | 42779840 | PubTator, text mining | PubMed |
| Laminin β4 is required for the development of human peripheral sensory neurons. | Development | 2026 | 42690250 | PubTator, text mining | PubMed |
| CD39+CD103+CD8+ T cells enhance neoadjuvant chemoimmunotherapy efficacy in head and neck squamous cell carcinoma. | Br J Cancer | 2026 | 42618591 | PubTator, text mining | PubMed |
| Nanofibrous Matrices Modulating Glioma Cell Migration and Proliferation and the Exploration of Their Molecular Mechanism. | ACS Appl Bio Mater | 2026 | 42606053 | PubTator, text mining | PubMed |
| Decoding the Complexity of Hepatocellular Carcinoma: Clinical Challenges and Targeting HuR as a Novel Therapeutic Strategy. | Livers | 2026 | 42583674 | PubTator, text mining | PubMed |
| Plectin 1d Isoform as a Potential Regulator of Metastatic Progression in Papillary Thyroid Carcinoma. | Int J Mol Sci | 2026 | 42511682 | PubTator, text mining | PubMed |
| Co-Assembling 3D In Vitro Model to Recreate the Colorectal Tumor Microenvironment. | Adv Healthc Mater | 2026 | 42216422 | PubTator, text mining | PubMed |
| A transcriptionally distinct population of human adipocytes with end-of-trajectory signature (hEOS) emerges during obesity to drive maladaptive inflammation. | Pharmacol Res | 2026 | 42107509 | PubTator, text mining | PubMed |
1 to 10 of 1,288
See all 1,288 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3910
GET https://conductscience.org/api/genes/v1/3910/patents?page=2