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Gene · 3914

LAMB3: laminin subunit beta 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LAMB3: laminin subunit beta 3. Genes, record 3914. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3914

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Gene

Symbol
LAMB3
HGNC
Name
laminin subunit beta 3
HGNC
NCBI Gene ID
3914
NCBI Gene
HGNC ID
HGNC:6490
HGNC
Ensembl
ENSG00000196878
NCBI Gene
Aliases
AI1A, BM600-125KDA, BM600-125kDa, JEB1A, JEB1B, LAM5, LAMNB1, kalinin-140kDa, nicein-125kDa
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q13751Laminin subunit beta-31,1720Ensembl, GeneID, HGNC

Source UniProt

Patents80

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026042028 A2026-03-1058Q13751Espacenet
JP 2026004568 A2026-01-1451117Q13751Espacenet
JP 2026004568 A2026-01-1451118Q13751Espacenet
JP 2026004568 A2026-01-1451119Q13751Espacenet
EP 4650780 A22025-11-197245Q13751Espacenet
EP 4641201 A22025-10-297181Q13751Espacenet
JP 2025147176 A2025-10-067685Q13751Espacenet
JP 2025147176 A2025-10-067686Q13751Espacenet
JP 2025147176 A2025-10-067687Q13751Espacenet
JP 2025529142 A2025-09-046856Q13751Espacenet

1 to 10 of 80

See all 80 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
OCRIPLASMINCHEMBL2095222Laminin hydrolytic enzymeHYDROLYTIC ENZYME

Source ChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02747030OCRIPLASMINPHASE1ClinicalTrials.gov
NCT02681809OCRIPLASMINPHASE22020-12-16ClinicalTrials.gov
NCT01429441OCRIPLASMINPHASE32016-01-11ClinicalTrials.gov
NCT00996684OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00798317OCRIPLASMINPHASE32013-01-30ClinicalTrials.gov
NCT00781859OCRIPLASMINPHASE32013-01-28ClinicalTrials.gov
NCT00428129OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00412451OCRIPLASMINPHASE22013-09-13ClinicalTrials.gov
NCT00123305OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00123266OCRIPLASMINPHASE2ClinicalTrials.gov

NIH grants920

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLAMB3 papersNewest fiscal year
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant72025
P30CA008748Cancer Center Support Grant52025
UL1TR001863Yale Clinical and Translational Science Award52025
P30CA062203Cancer Center Support Grant42025
P30CA006973Regional Oncology Research Center32025
P30CA068485Cancer Center Support Grant32025
P30CA006927Comprehensive Cancer Center Program at Fox Chase22025
P30CA014051Cancer Center Support (Core) Grant22025
P30CA016086Cancer Center Support Grant22025
P30CA033572Cancer Center Support Grant22025

1 to 10 of 920Source NIH's project files

See all 920 nih grants

Papers1,750

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A PepFect14 analog improves non-viral CRISPR delivery in primary human cells to facilitate genome editing and repair.Bioeng Transl Med202642666741PubTator, text miningPubMed
HPV16 E7-Associated SERPINB3 Suppression and MYC-Related Epithelial Plasticity in Head and Neck Squamous Cell Carcinoma.Cancers (Basel)202642588639PubTator, text miningPubMed
A prognostic risk model based on programmed cell death genes for breast cancer and its potential clinical application.Medicine (Baltimore)202642499036PubTator, text miningPubMed
S100A4 promotes collective invasion of pancreatic ductal adenocarcinoma and its blockade suppresses metastasis.Cell Commun Signal202642432705PubTator, text miningPubMed
LAMB3 drives gastric cancer progression through SAMD4A-mediated degradation of PHLPP2 mRNA leading to sustained PI3K-Akt activation.Br J Cancer202642310093PubTator, text miningPubMed
Deciphering the Pleiotropic Role of ARID1a and RIF1 in Endometrioid Ovarian Cancer.Cells202642274628PubTator, text miningPubMed
RNA binding protein YWHAZ mediates specific mRNA translation and regulates cell proliferation and apoptosis in diabetic foot ulcer.Front Med (Lausanne)202642180716PubTator, text miningPubMed
Tumor-Derived LAMB3 Drives Immunosuppressive LRRC15+ Fibroblast Formation During Pancreatic Ductal Adenocarcinoma Development.Adv Sci (Weinh)202642154006PubTator, text miningPubMed
An integrated single-cell and spatial proteotranscriptomics atlas of fibroblast-driven immunoregulation within the human adult oral cavity.Cell Press Blue202642147490PubTator, text miningPubMed
Insights into Copy Number Variation Architecture in Black Bengal Goat Genome.Int J Mol Sci202642123621PubTator, text miningPubMed

1 to 10 of 1,750

See all 1,750 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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The record and each of its lists are JSON, twenty rows a page. No key.

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