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Gene · 3915

LAMC1: laminin subunit gamma 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LAMC1: laminin subunit gamma 1. Genes, record 3915. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3915

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Gene

Symbol
LAMC1
HGNC
Name
laminin subunit gamma 1
HGNC
NCBI Gene ID
3915
NCBI Gene
HGNC ID
HGNC:6492
HGNC
Ensembl
ENSG00000135862
NCBI Gene
Aliases
LAMB2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P11047Laminin subunit gamma-11,6094Ensembl, GeneID, HGNC

Source UniProt

Patents88

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1451122P11047Espacenet
WO 2025259943 A12025-12-1825P11047Espacenet
EP 4650780 A22025-11-191680P11047Espacenet
EP 4641201 A22025-10-291285P11047Espacenet
JP 2025147176 A2025-10-067693P11047Espacenet
JP 2025529142 A2025-09-046858P11047Espacenet
US 12371689 B22025-07-296858P11047Espacenet
JP 2025517969 A2025-06-121285P11047Espacenet
JP 2025517970 A2025-06-121680P11047Espacenet
JP 2025028160 A2025-02-287693P11047Espacenet

1 to 10 of 88

See all 88 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
OCRIPLASMINCHEMBL2095222Laminin hydrolytic enzymeHYDROLYTIC ENZYME

Source ChEMBL

Trials10

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT02747030OCRIPLASMINPHASE1ClinicalTrials.gov
NCT02681809OCRIPLASMINPHASE22020-12-16ClinicalTrials.gov
NCT01429441OCRIPLASMINPHASE32016-01-11ClinicalTrials.gov
NCT00996684OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00798317OCRIPLASMINPHASE32013-01-30ClinicalTrials.gov
NCT00781859OCRIPLASMINPHASE32013-01-28ClinicalTrials.gov
NCT00428129OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00412451OCRIPLASMINPHASE22013-09-13ClinicalTrials.gov
NCT00123305OCRIPLASMINPHASE2ClinicalTrials.gov
NCT00123266OCRIPLASMINPHASE2ClinicalTrials.gov

NIH grants1,164

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLAMC1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant52025
P30CA015704Cancer Center Support Grant52025
U01CA167551Colon Cancer Family Registry Cohort52025
P30CA006973Regional Oncology Research Center42025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)42025
P30CA062203Cancer Center Support Grant42025
P30AG066511Goizueta Alzheimer's Disease Research Center32025
P30CA010815Consolidated Basic Cancer Research Program32025
P30CA016087Cancer Center Support Grant32025
P30CA068485Cancer Center Support Grant32025

1 to 10 of 1,164Source NIH's project files

See all 1,164 nih grants

Papers1,504

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Exosome-Mediated Bidirectional Signaling Regulates Glioma Stem-Cell Homeostasis and Radiation-Induced Plasticity.bioRxiv202642818566PubTator, text miningPubMed
Single-Cell RNA Sequencing of Uterine Tissue from a 70-Day-Old Female Rabbit: Cellular Composition and Fibroblast-Associated Networks.Genes (Basel)202642793025PubTator, text miningPubMed
Functional role of LAMC1 in modulating cuproptosis in glioma cells.Biochim Biophys Acta Mol Cell Res202642665028PubTator, text miningPubMed
Epidemiological Trends and Shared Molecular Signatures of Pancreatic Ductal Adenocarcinoma and Diabetes: An Integrative Analysis Based on Global Burden of Disease and Gene Expression Omnibus Datasets.J Cancer202642327586PubTator, text miningPubMed
Multifaceted roles of miR‑124 in cancer: Molecular mechanisms and clinical prospects (Review).Int J Oncol202641891957PubTator, text miningPubMed
Unraveling small non-coding RNAs with a significant post-transcriptional impact on breast cancer cell signaling, using a combinational sequencing approach.Funct Integr Genomics202641866548PubTator, text miningPubMed
Pro-Homeostatic Effects of Estrogen on Intraocular Pressure and the Trabecular Meshwork.Invest Ophthalmol Vis Sci202641800843PubTator, text miningPubMed
Single-Cell RNA Sequencing Reveals the Cellular and Molecular Differences Between Myxofibrosarcoma and Undifferentiated Pleomorphic Sarcoma.Med Sci (Basel)202641718124PubTator, text miningPubMed
Identification of Basement Membrane-Related Biomarkers in the Progression of Cutaneous Squamous Cell Carcinoma.Int J Mol Sci202641683815PubTator, text miningPubMed
Autoantibodies as predictors for immune-related adverse events in checkpoint inhibition therapy of metastatic melanoma.J Immunother Cancer202641592893PubTator, text miningPubMed

1 to 10 of 1,504

See all 1,504 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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