Gene · 392
ARHGAP1: Rho GTPase activating protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. ARHGAP1: Rho GTPase activating protein 1. Genes, record 392. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/392
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q07960 | Rho GTPase-activating protein 1 | 439 | 11 | Ensembl, GeneID, HGNC |
Source UniProt
Patents31
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 61667 | Q07960 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 4694 | Q07960 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 439 | Q07960 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 439 | Q07960 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 4694 | Q07960 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 73190 | Q07960 | Espacenet |
| US 11400116 B2 | 2022-08-02 | 3014 | Q07960 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 176161 | Q07960 | Espacenet |
| US 11078247 B2 | 2021-08-03 | 710 | Q07960 | Espacenet |
| US 10859577 B2 | 2020-12-08 | 3 | Q07960 | Espacenet |
1 to 10 of 31
See all 31 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,314
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | ARHGAP1 papers | Newest fiscal year |
|---|---|---|---|
| P30DK045735 | Yale Diabetes Research Center | 8 | 2025 |
| ZIABC007365 | Regulation of ADP-ribosylation factor | 8 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 7 | 2025 |
| P30DA018343 | Yale/NIDA Neuroproteomics Center | 7 | 2025 |
| ZIABC008905 | Tumor gene expression in vitro and in vivo | 7 | 2025 |
| R01AR041398 | Novel Molecular Biomarkers of Bone Microarchitecture | 6 | 2025 |
| P40OD010440 | Caenorhabditis Genetics Center | 5 | 2025 |
| R01DK064380 | Molecular Mechanisms Regulating Epithelial Cell Apical Polarity and Ciliogenesis | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
1 to 10 of 1,314Source NIH's project files
See all 1,314 nih grantsPapers1,758
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| How Functional Variants Reconfigure the Rac2 Conformational Landscape. | J Phys Chem B | 2026 | 42593131 | PubTator, text mining | PubMed |
| A Rho GTPase-activating protein plays a positive role in tobacco resistance against chili veinal mottle virus. | Plant Physiol | 2026 | 42478924 | PubTator, text mining | PubMed |
| Transcriptomic Profiling and WGCNA Identify ALOX5 as a Key Regulator of Iron Metabolism and Immune Crosstalk in Venous Thromboembolism. | Curr Issues Mol Biol | 2026 | 42353611 | PubTator, text mining | PubMed |
| Extracellular vesicle cargo dynamics in the bone marrow microenvironment: from hematopoietic homeostasis to malignant transformation. | Extracell Vesicle | 2026 | 42344609 | PubTator, text mining | PubMed |
| Glutamine Tautomerization Drives RhoGAP-Aided GTP Hydrolysis in Small Rho GTPases. | J Am Chem Soc | 2026 | 42297792 | PubTator, text mining | PubMed |
| The multifaceted role of FAM13A in pulmonary diseases. | Front Genet | 2026 | 42266412 | PubTator, text mining | PubMed |
| How Functional Variants Reconfigure the Rac2 Conformational Landscape. | bioRxiv | 2026 | 42039397 | PubTator, text mining | PubMed |
| DEPDC7 as a potential tumor suppressor in hepatocellular carcinoma: preliminary evidence for targeting the JAK1/STAT3 axis. | Front Oncol | 2026 | 41930189 | PubTator, text mining | PubMed |
| Neuronal ARHGAP8 controls synapse structure and AMPA receptor-mediated synaptic transmission. | Commun Biol | 2026 | 41862576 | PubTator, text mining | PubMed |
| Duplication of the prothrombin gene is associated with a significant increase in thrombin generation. | Res Pract Thromb Haemost | 2026 | 41769318 | PubTator, text mining | PubMed |
1 to 10 of 1,758
See all 1,758 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/392
GET https://conductscience.org/api/genes/v1/392/patents?page=2