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Gene · 3936

LCP1: lymphocyte cytosolic protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LCP1: lymphocyte cytosolic protein 1. Genes, record 3936. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3936

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Gene

Symbol
LCP1
HGNC
Name
lymphocyte cytosolic protein 1
HGNC
NCBI Gene ID
3936
NCBI Gene
HGNC ID
HGNC:6528
HGNC
Ensembl
ENSG00000136167
NCBI Gene
Aliases
CP64, HEL-S-37, L-PLASTIN, LC64P, PLS2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P13796Plastin-26274Ensembl, GeneID, HGNC

Source UniProt

Patents39

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026063308 A2026-03-2627P13796Espacenet
JP 2026004568 A2026-01-1452018P13796Espacenet
JP 2026004568 A2026-01-1452019P13796Espacenet
EP 4641201 A22025-10-294616P13796Espacenet
JP 2025517969 A2025-06-124616P13796Espacenet
WO 2024231697 A12024-11-146P13796Espacenet
KR 1020230123458 A2023-08-2312P13796Espacenet
US 11446398 B22022-09-2047566P13796Espacenet
US 11446398 B22022-09-2047567P13796Espacenet
JP 2022524081 A2022-04-27150537P13796Espacenet

1 to 10 of 39

See all 39 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants909

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLCP1 papersNewest fiscal year
P30CA008748Cancer Center Support Grant62025
R01GM114666Molecular Mechanisms of Bacterial Toxins Targeting the Actin Cytoskeleton62025
R01GM145813Molecular and cellular mechanisms of the actin cytoskeleton organization and function42025
R01NS034239Neuroprotective Immunity and HIV Dementia42025
P30CA023108Cancer Center Support Grant32025
P41GM108538National Center for Quantitative Biology of Complex Systems32025
R35GM122510Cryo-EM of Helical Protein and Nucleoprotein Polymers at Near Atomic Resolution32025
UL1TR001863Yale Clinical and Translational Science Award32025
UL1TR001881UCLA Clinical and Translational Science Institute32025
I01CX001696Platelet Reprogramming During Inflammation22025

1 to 10 of 909Source NIH's project files

See all 909 nih grants

Papers1,318

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Autosomal dominant gain-of-function mutations in LCP1 cause a syndromic neutropenia and immunodeficiency.Genes Dis202742763497PubTator, text miningPubMed
Deciphering the Genetic Underpinnings of Liver Cirrhosis-Heart Failure Comorbidity Through Multi-Omics: CRIM1 as a Key Endothelial Mediator.Int J Mol Sci202642737833PubTator, text miningPubMed
Differential protein abundance in colostrum-derived extracellular vesicles from bovine leukemia virus-infected cattle are implicated in immune regulation and inflammation.Front Immunol202642591436PubTator, text miningPubMed
Differential transcript usage in the placenta in early onset preeclampsia.Placenta202642497590PubTator, text miningPubMed
Exploring LTB-mediated T cell differentiation as a prognostic marker in triple-negative breast cancer.Breast Cancer Res202642381077PubTator, text miningPubMed
Mapping topological abnormalities in cortical similarity networks to schizophrenia-associated gene expression.Dialogues Clin Neurosci202642316880PubTator, text miningPubMed
Macrophage immunometabolism in stroke: a view from single-cell and nano technologies.J Transl Med202642286638PubTator, text miningPubMed
Prediction of immune-related adverse events in urological cancer during checkpoint inhibitor immunotherapy through immunohistochemical analysis of tumorous LCP1/ADPGK.Transl Oncol202642241990PubTator, text miningPubMed
A Nanobody-LNP Platform for Targeting and Relicensing Dendritic Cells for Potent Cancer Immunotherapy.Adv Sci (Weinh)202642080357PubTator, text miningPubMed
Proteogenomic detection of tumor-specific somatic mutant proteins in urinary extracellular vesicles for non-invasive monitoring of bladder cancer.Front Oncol202642063735PubTator, text miningPubMed

1 to 10 of 1,318

See all 1,318 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3936

GET https://conductscience.org/api/genes/v1/3936/patents?page=2