Gene · 3945
LDHB: lactate dehydrogenase B
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LDHB: lactate dehydrogenase B. Genes, record 3945. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3945
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P07195 | L-lactate dehydrogenase B chain | 334 | 7 | Ensembl, GeneID, HGNC |
Source UniProt
Patents89
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 51042 | P07195 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 51044 | P07195 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 735 | P07195 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 39029 | P07195 | Espacenet |
| US 12433933 B2 | 2025-10-07 | 54 | P07195 | Espacenet |
| US 12433933 B2 | 2025-10-07 | 6 | P07195 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 39029 | P07195 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 735 | P07195 | Espacenet |
| JP 2024504467 A | 2024-01-31 | 2 | P07195 | Espacenet |
| JP 2024009871 A | 2024-01-23 | 103 | P07195 | Espacenet |
1 to 10 of 89
See all 89 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,624
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LDHB papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 17 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 12 | 2025 |
| P41EB013598 | Hyperpolarized MRI Technology Resource Center | 6 | 2025 |
| P30CA010815 | Consolidated Basic Cancer Research Program | 5 | 2025 |
| P30CA125123 | Baylor College of Medicine Cancer Center - Cancer Center Support Grant | 5 | 2025 |
| P50HD103526 | MIND Institute Intellectual and Developmental Disabilities Research Center | 5 | 2025 |
| R01CA051497 | Defining the Role of the Cancer Circadian Clock in Tumor Immunity and Tumorigenesis | 5 | 2025 |
| R35CA220449 | Human metabolic variation as a window into cancer initiation and progression | 5 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 4 | 2025 |
| P30CA056036 | Translational Research in Cancer | 4 | 2025 |
1 to 10 of 1,624Source NIH's project files
See all 1,624 nih grantsPapers2,881
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| TLR7/9 and type I interferon signaling reprogram neutrophil NET responses and impair antibacterial defense in systemic lupus erythematosus. | Cell Press Blue | 2026 | 42746563 | PubTator, text mining | PubMed |
| Malic enzyme 1 senses L-lactate to determine tumor heterogeneity. | Signal Transduct Target Ther | 2026 | 42728262 | PubTator, text mining | PubMed |
| Disulfidptosis as an immunometabolic rheostat in gastrointestinal cancers: tuning the balance between T Cell exhaustion and immunogenic cell death. | Front Cell Dev Biol | 2026 | 42724329 | PubTator, text mining | PubMed |
| PHB2 Promotes Glycolytic Reprogramming in Triple-Negative Breast Cancer Through FOXM1-Dependent Activation of LDHB. | Carcinogenesis | 2026 | 42710061 | PubTator, text mining | PubMed |
| Lactylation in sepsis-associated acute kidney injury: regulatory mechanisms and therapeutic prospects. | Front Mol Biosci | 2026 | 42688716 | PubTator, text mining | PubMed |
| The dual role of the cGAS-STING signaling pathway in kidney diseases: from acute injury to chronic fibrosis - molecular mechanisms and precision therapeutic strategies. | Front Pharmacol | 2026 | 42621049 | PubTator, text mining | PubMed |
| Multi-omics-guided identification of blood-entering bioactive components and candidate responsive targets of Shugan Jianpi Tiaochang Pill against colorectal adenoma. | Phytomedicine | 2026 | 42607381 | PubTator, text mining | PubMed |
| Metabolic reprogramming via LDHB confers resistance to lactate-induced dysfunction and enhanced antitumor activity in hiPSC-Derived NK cells. | Stem Cell Reports | 2026 | 42594863 | PubTator, text mining | PubMed |
| Ozone Hydrotherapy Improves Seborrheic Dermatitis by Regulating Scalp Microbiome and Mitochondrial Lactate Shuttle in Keratinocytes. | J Infect Dis | 2026 | 42586552 | PubTator, text mining | PubMed |
| Metabolic reprogramming is associated with symptomatic COVID-19: a serum proteomics and causal inference study identifying ALDOB and glycerol as candidate metabolic correlates. | Front Microbiol | 2026 | 42568671 | PubTator, text mining | PubMed |
1 to 10 of 2,881
See all 2,881 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/3945
GET https://conductscience.org/api/genes/v1/3945/patents?page=2