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LDLR: low density lipoprotein receptor

1 protein, 171 patents, 0 drugs, 0 trials, 9,840 NIH grants and 23,071 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolLDLRHGNC
Namelow density lipoprotein receptorHGNC
NCBI Gene ID3949NCBI Gene
HGNC IDHGNC:6547HGNC
EnsemblENSG00000130164NCBI Gene
AliasesLDLCQ2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P01130Low-density lipoprotein receptor86036Ensembl, GeneID, HGNCUniProt

Patents 171

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026124628 A2026-07-311P01130Espacenet
JP 2026515163 A2026-05-145P01130Espacenet
JP 2026067851 A2026-04-21148P01130Espacenet
JP 2026047184 A2026-03-131P01130Espacenet
JP 2025188163 A2025-12-2524P01130Espacenet
EP 4650780 A22025-11-1916955P01130Espacenet
JP 2025169942 A2025-11-141149P01130Espacenet
WO 2025231085 A12025-11-062P01130Espacenet
WO 2025231085 A12025-11-0671P01130Espacenet
WO 2025231085 A12025-11-0675P01130Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 9840

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK063491Diabetes Research Center (DRC)462,025NIH's project files
U01HG006379EHR-based Genomic Discovery and Implementation [Funded Extension]322,025NIH's project files
P30DK017047Diabetes Research Center302,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)202,025NIH's project files
P01HL136275Immune Cell Interactions in Atherosclerosis192,025NIH's project files
P01HL131481Macrophage Dysfunction in Atherosclerosis and Cardiometabolic Diseases182,025NIH's project files
P30CA016672Cancer Center Support Grant182,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)182,025NIH's project files
UL1TR001881UCLA Clinical and Translational Science Institute182,025NIH's project files
P30CA008748Cancer Center Support Grant172,025NIH's project files

Papers 23071

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824094PubTator, text miningPubMed
42822817PubTator, text miningPubMed
42814397PubTator, text miningPubMed
42812038PubTator, text miningPubMed
42808173PubTator, text miningPubMed
42806956PubTator, text miningPubMed
42799026PubTator, text miningPubMed
42798781PubTator, text miningPubMed
42792950PubTator, text miningPubMed
42791183PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license