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LGALS3: galectin 3

1 protein, 166 patents, 3 drugs, 14 trials, 5,577 NIH grants and 14,742 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolLGALS3HGNC
Namegalectin 3HGNC
NCBI Gene ID3958NCBI Gene
HGNC IDHGNC:6563HGNC
EnsemblENSG00000131981NCBI Gene
AliasesCBP35, GAL3, GALBP, GALIG, L31, LGALS2, MAC-2, MAC2NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P17931Galectin-3250172Ensembl, GeneID, HGNCUniProt

Patents 166

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4796119 A12026-08-261P17931Espacenet
JP 2026088136 A2026-05-281P17931Espacenet
JP 2026064238 A2026-04-1381P17931Espacenet
JP 2026064238 A2026-04-13609P17931Espacenet
JP 2026048820 A2026-03-171P17931Espacenet
JP 2026048820 A2026-03-174P17931Espacenet
EP 4684799 A22026-01-281P17931Espacenet
EP 4663762 A22025-12-1735P17931Espacenet
US 12497458 B22025-12-161P17931Espacenet
EP 4654993 A12025-12-0360P17931Espacenet

Drugs 3

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
BELAPECTINCHEMBL4297577Galectin-3 inhibitorINHIBITORChEMBL
DAVANATCHEMBL4297960Galectin-3 inhibitorINHIBITORChEMBL
OLITIGALTINCHEMBL4297442Galectin-3 inhibitorINHIBITORChEMBL

Trials 14

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT04987996BELAPECTINPHASE2ClinicalTrials.gov
NCT04473053OLITIGALTINPHASE1/PHASE2ClinicalTrials.gov
NCT03832946OLITIGALTINPHASE22024-05-22ClinicalTrials.gov
NCT02575404BELAPECTINPHASE1ClinicalTrials.gov
NCT02462967BELAPECTINPHASE22020-10-08ClinicalTrials.gov
NCT02421094BELAPECTINPHASE22020-09-28ClinicalTrials.gov
NCT02407041BELAPECTINPHASE22020-09-07ClinicalTrials.gov
NCT02257177OLITIGALTINPHASE1/PHASE22021-04-08ClinicalTrials.gov
NCT02117362BELAPECTINPHASE1ClinicalTrials.gov
NCT01899859BELAPECTINPHASE1ClinicalTrials.gov

NIH grants 5577

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant442,025NIH's project files
P30CA008748Cancer Center Support Grant302,025NIH's project files
R01CA097098Targeting the MUC1-C Oncoprotein in Triple-Negative Breast Cancer172,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award162,025NIH's project files
R01EY026147Glycosylation in ocular surface health and disease132,025NIH's project files
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.112,025NIH's project files
P30CA006973Regional Oncology Research Center112,025NIH's project files
P30DK063491Diabetes Research Center (DRC)112,025NIH's project files
P30EY003790Core Grant for Vision Research112,025NIH's project files
P30CA076292Moffitt Cancer Center Support Grant102,025NIH's project files

Papers 14742

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42824873PubTator, text miningPubMed
42823738PubTator, text miningPubMed
42819567PubTator, text miningPubMed
42808395PubTator, text miningPubMed
42807193PubTator, text miningPubMed
42806128PubTator, text miningPubMed
42800570PubTator, text miningPubMed
42800378PubTator, text miningPubMed
42796241PubTator, text miningPubMed
42794855PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license