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Gene · 3972

LHB: luteinizing hormone subunit beta

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LHB: luteinizing hormone subunit beta. Genes, record 3972. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/3972

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Gene

Symbol
LHB
HGNC
Name
luteinizing hormone subunit beta
HGNC
NCBI Gene ID
3972
NCBI Gene
HGNC ID
HGNC:6584
HGNC
Ensembl
ENSG00000104826
NCBI Gene
Aliases
CGB4, HH23, LSH-B, LSH-beta, hLHB
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P01229Lutropin subunit beta1410Ensembl, GeneID, HGNC

Source UniProt

Patents75

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4725503 A22026-04-152328P01229Espacenet
JP 2026035690 A2026-03-042328P01229Espacenet
JP 2026021445 A2026-02-102763P01229Espacenet
JP 2026501516 A2026-01-1643399P01229Espacenet
EP 4650780 A22025-11-1919597P01229Espacenet
JP 2025169942 A2025-11-141152P01229Espacenet
EP 4646428 A12025-11-1243399P01229Espacenet
US 12447196 B22025-10-214P01229Espacenet
JP 2025147176 A2025-10-067850P01229Espacenet
KR 1020250133399 A2025-09-0543399P01229Espacenet

1 to 10 of 75

See all 75 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants779

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLHB papersNewest fiscal year
T32HD007203Training in Reproductive Sciences112025
P01AG029531The Aging Pituitary/Gonadal Axis92025
P30DK063491Diabetes Research Center (DRC)62025
R01DK046943Integrated systems biology of the pituitary62025
T32ES007326Interdisciplinary Research Training Program in Environmental Health and Toxicology52025
ZIAHD000195Intracellular Signaling In Endocrine Cells52025
P30CA047904Cancer Center Support Grant42025
K12GM068524San Diego IRACDA Scholars Program32025
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 522025
P30CA016672Cancer Center Support Grant22025

1 to 10 of 779Source NIH's project files

See all 779 nih grants

Papers1,853

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Cross-Cohort Characterization of an LHB-Associated Transcriptomic State in Prostate Cancer.Prostate202642762535PubTator, text miningPubMed
Differential effects of acute, chronic, and social defeat stress on microglial morphology in the basolateral and central amygdala, and the medial and lateral habenula.Brain Struct Funct202642696151PubTator, text miningPubMed
Generation of Functional GnRH-Responsive Pituitary-like Organoids from Ovine Embryonic Stem Cells.Cells202642587770PubTator, text miningPubMed
Developmental lead exposure fractures the hypothalamic-pituitary-gonadal axis in dams: mechanistic insights into primary ovarian failure and central bioenergetic bottlenecks.Naunyn Schmiedebergs Arch Pharmacol202642461322PubTator, text miningPubMed
Molecular Mechanisms of Dysregulated LH and FSH Secretion in Human Reproductive Failure.Biomedicines202642072331PubTator, text miningPubMed
Diagnostic Criteria and Genetic Basis of Polycystic Ovary Syndrome: A Narrative Review.Metabolites202642042922PubTator, text miningPubMed
Genetic Anatomy and Ontogenetic Roles of Early Growth Response 1 (Egr1) in Human and Mouse.Dev Reprod202642004051PubTator, text miningPubMed
An HBV-Derived Peptide Poly6 as a Novel Candidate for Functional Cure Via IFN-I-Mediated Epigenetic Regulation of cccDNA.J Med Virol202641891511PubTator, text miningPubMed
Immunization Against a Conserved Short 13-Amino Acid Receptor-Binding Epitope of FSHβ Reduces Spermatogenesis and Sperm Motility in Male Mice.Vaccines (Basel)202641746104PubTator, text miningPubMed
Construction of an Adverse Outcome Pathway Framework for Glyphosate-Induced Female Reproductive Toxicity Based on Toxicity Pathways.Environ Health (Wash)202641743805PubTator, text miningPubMed

1 to 10 of 1,853

See all 1,853 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/3972

GET https://conductscience.org/api/genes/v1/3972/patents?page=2