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Gene · 3980

Papers1,941

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

521 to 540 of 1,941

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TitleJournalYearPMIDFound bySource
Rac GTPase activating protein 1 promotes gallbladder cancer via binding DNA ligase 3 to reduce apoptosis.Int J Biol Sci202134239347PubTator, text miningPubMed
DNA damage repair: historical perspectives, mechanistic pathways and clinical translation for targeted cancer therapy.Signal Transduct Target Ther202134238917PubTator, text miningPubMed
Long-chain polyphosphates impair SARS-CoV-2 infection and replication.Sci Signal202134230209PubTator, text miningPubMed
Replication gaps are a key determinant of PARP inhibitor synthetic lethality with BRCA deficiency.Mol Cell202134216544PubTator, text miningPubMed
Therapy Prospects for Mitochondrial DNA Maintenance Disorders.Int J Mol Sci202134208592PubTator, text miningPubMed
Molecular Mechanisms Regulating the DNA Repair Protein APE1: A Focus on Its Flexible N-Terminal Tail Domain.Int J Mol Sci202134208390PubTator, text miningPubMed
Regulatory and Functional Involvement of Long Non-Coding RNAs in DNA Double-Strand Break Repair Mechanisms.Cells202134203749PubTator, text miningPubMed
Targeting the Ubiquitin-Proteasome System for Cancer Therapeutics by Small-Molecule Inhibitors.Cancers (Basel)202134203106PubTator, text miningPubMed
Analyzing the Opportunities to Target DNA Double-Strand Breaks Repair and Replicative Stress Responses to Improve Therapeutic Index of Colorectal Cancer.Cancers (Basel)202134201502PubTator, text miningPubMed
Exploiting DNA Endonucleases to Advance Mechanisms of DNA Repair.Biology (Basel)202134198612PubTator, text miningPubMed
Direct interaction of DNA repair protein tyrosyl DNA phosphodiesterase 1 and the DNA ligase III catalytic domain is regulated by phosphorylation of its flexible N-terminus.J Biol Chem202134181949PubTator, text miningPubMed
Genotoxic therapy and resistance mechanism in gliomas.Pharmacol Ther202134171339PubTator, text miningPubMed
Myopathic mitochondrial DNA depletion syndrome associated with biallelic variants in LIG3.Brain202134165507Swiss-Prot, curatedPubMed
UPF1 promotes the formation of R loops to stimulate DNA double-strand break repair.Nat Commun202134158508PubTator, text miningPubMed
Damage-Net: A program for DNA repair meta-analysis identifies a network of novel repair genes that facilitate cancer evolution.DNA Repair (Amst)202134147942PubTator, text miningPubMed
Polθ inhibitors elicit BRCA-gene synthetic lethality and target PARP inhibitor resistance.Nat Commun202134140467PubTator, text miningPubMed
Azacytidine plus olaparib for relapsed acute myeloid leukaemia, ineligible for intensive chemotherapy, diagnosed with a synchronous malignancy.J Cell Mol Med202134132464PubTator, text miningPubMed
DNA damage and regulation of protein homeostasis.DNA Repair (Amst)202134116476PubTator, text miningPubMed
UHRF2 commissions the completion of DNA demethylation through allosteric activation by 5hmC and K33-linked ubiquitination of XRCC1.Mol Cell202134111398PubTator, text miningPubMed
XRCC1 prevents toxic PARP1 trapping during DNA base excision repair.Mol Cell202134102106PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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