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LIPE: lipase E, hormone sensitive type

1 protein, 28 patents, 0 drugs, 0 trials, 2,176 NIH grants and 4,734 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolLIPEHGNC
Namelipase E, hormone sensitive typeHGNC
NCBI Gene ID3991NCBI Gene
HGNC IDHGNC:6621HGNC
EnsemblENSG00000079435NCBI Gene
AliasesAOMS4, FPLD6, HSL, LHS, REHNCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
Q05469Hormone-sensitive lipase1,0761Ensembl, GeneID, HGNCUniProt

Patents 28

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4705273 A22026-03-11521Q05469Espacenet
JP 2026004568 A2026-01-1451834Q05469Espacenet
EP 4641201 A22025-10-29790Q05469Espacenet
JP 2025517969 A2025-06-12790Q05469Espacenet
JP 2025013347 A2025-01-24521Q05469Espacenet
EP 4406585 A22024-07-31521Q05469Espacenet
JP 2023011696 A2023-01-24521Q05469Espacenet
JP 2023011697 A2023-01-24521Q05469Espacenet
US 11446398 B22022-09-2046979Q05469Espacenet
JP 2022539377 A2022-09-08375Q05469Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 2176

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30DK020572Michigan Diabetes Research Center (MDRC)232,025NIH's project files
P30DK089503Michigan Nutrition Obesity Research Center162,025NIH's project files
P30DK056341Washington University Nutrition Obesity Research Center122,025NIH's project files
R01DK105448Genetic and Metabolic Basis of Familial Lipodystrophies92,025NIH's project files
P30DK020541NYR-Diabetes Research Center (NYR-DRC)82,025NIH's project files
P30DK020579Diabetes Research Center82,025NIH's project files
P30DK036836Diabetes Research Center82,025NIH's project files
P30DK056350Nutrition Obesity Research Center (NORC)82,025NIH's project files
P51OD011092Support for National Primate Research Center82,025NIH's project files
P30DK026743UCSF Liver Center62,025NIH's project files

Papers 4734

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42794967PubTator, text miningPubMed
42675379PubTator, text miningPubMed
42664245PubTator, text miningPubMed
42600821PubTator, text miningPubMed
42557353PubTator, text miningPubMed
42538432PubTator, text miningPubMed
42523439PubTator, text miningPubMed
42481310PubTator, text miningPubMed
42465489PubTator, text miningPubMed
42419629PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license