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LMNA: lamin A/C

1 protein, 87 patents, 0 drugs, 0 trials, 9,132 NIH grants and 17,060 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolLMNAHGNC
Namelamin A/CHGNC
NCBI Gene ID4000NCBI Gene
HGNC IDHGNC:6636HGNC
EnsemblENSG00000160789NCBI Gene
AliasesCDCD1, CDDC, CMD1A, CMT2B1, EMD2, FPL, FPLD, FPLD2, HGPS, IDC, LDP1, LFP, LGMD1B, LMN1, LMNC, LMNL1, MADA, PRO1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P02545Prelamin-A/C66428Ensembl, GeneID, HGNCUniProt

Patents 87

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4824266 A12026-10-2152P02545Espacenet
EP 4773979 A12026-07-15172P02545Espacenet
JP 2026518827 A2026-06-1020P02545Espacenet
US 12564647 B22026-03-03208P02545Espacenet
EP 4689118 A12026-02-1120P02545Espacenet
JP 2026004568 A2026-01-1451066P02545Espacenet
JP 2026000906 A2026-01-06226P02545Espacenet
EP 4650780 A22025-11-198425P02545Espacenet
EP 4641202 A22025-10-295425P02545Espacenet
WO 2025125705 A12025-06-192P02545Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 9132

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA008748Cancer Center Support Grant722,025NIH's project files
P30CA016672Cancer Center Support Grant492,025NIH's project files
ZIABC010309Nuclear Architecture and Disease392,025NIH's project files
P30CA010815Consolidated Basic Cancer Research Program322,025NIH's project files
P30CA014195Cancer Center Support Grant (CCSG)262,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center232,025NIH's project files
ZIAHG200305Hutchinson-Gilford Progeria syndrome--a model for the genetics of aging.222,025NIH's project files
P30DK020572Michigan Diabetes Research Center (MDRC)202,025NIH's project files
ZIANS003129Molecular and Clinical Manifestations of Matrix and Aggregate Myopathies202,025NIH's project files
P40OD010440Caenorhabditis Genetics Center192,025NIH's project files

Papers 17060

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818534PubTator, text miningPubMed
42818222PubTator, text miningPubMed
42816477PubTator, text miningPubMed
42815839PubTator, text miningPubMed
42814851PubTator, text miningPubMed
42814033PubTator, text miningPubMed
42810629PubTator, text miningPubMed
42783972PubTator, text miningPubMed
42781858PubTator, text miningPubMed
42781677PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license