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Gene · 4005

LMO2: LIM domain only 2

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LMO2: LIM domain only 2. Genes, record 4005. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4005

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Gene

Symbol
LMO2
HGNC
Name
LIM domain only 2
HGNC
NCBI Gene ID
4005
NCBI Gene
HGNC ID
HGNC:6642
HGNC
Ensembl
ENSG00000135363
NCBI Gene
Aliases
LMO-2, RBTN2, RBTNL1, RHOM2, TTG2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P25791Rhombotin-21584Ensembl, GeneID, HGNC

Source UniProt

Patents46

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4640849 A22025-10-291767P25791Espacenet
EP 4641201 A22025-10-2911801P25791Espacenet
JP 2025147176 A2025-10-0616607P25791Espacenet
JP 2025519096 A2025-06-241767P25791Espacenet
JP 2025517969 A2025-06-1211801P25791Espacenet
JP 2025032204 A2025-03-1130885P25791Espacenet
JP 2025028160 A2025-02-2816607P25791Espacenet
KR 1020250010750 A2025-01-2116607P25791Espacenet
EP 4461818 A22024-11-1330885P25791Espacenet
JP 2024123008 A2024-09-106830P25791Espacenet

1 to 10 of 46

See all 46 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,891

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLMO2 papersNewest fiscal year
P30CA021765Cancer Center Support Grant (CCSG)332025
P30CA008748Cancer Center Support Grant202025
P30CA016672Cancer Center Support Grant142025
P30CA068485Cancer Center Support Grant132025
R35CA197695Translating genomic discoveries to improved outcomes for high risk acute leukemia112025
I01BX001799Pathophysiology of Adult T-cell leukemia/lymphoma92025
P30DK058404Molecular and Cellular Basis for Digestive Diseases82025
P30CA036727Buffett Cancer Center Support Grant72025
ZIADK075033Chromatin Structure, Epigenetic and Developmental Regulation of Mammalian Gene72025
R01CA166835Targeted therapy for t(8;21)+ AML62025

1 to 10 of 1,891Source NIH's project files

See all 1,891 nih grants

Papers2,403

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Correction: Degradation of LMO2 in T cell leukaemia results in collateral breakdown of transcription complex partners and causes LMO2-dependent apoptosis.Elife202642766340PubTator, text miningPubMed
The machine-learning classifier ALLCatchR2 identifies 20 T-ALL subtypes across cohorts and age groups.Hemasphere202642741738PubTator, text miningPubMed
High Histological Skeletonization as a Measure of Heterogeneity Is Associated with Poor Overall Survival and Death Within 2 Years of Diffuse Large B-Cell Lymphoma.Cancers (Basel)202642738349PubTator, text miningPubMed
LMO2 regulates STAT3 localization to the nucleus in breast cancer cells.MicroPubl Biol202642602493PubTator, text miningPubMed
Acute erythroid leukaemia transformation in polycythaemia vera with leukemic involvement in liver and ascites.BMJ Case Rep202642547260PubTator, text miningPubMed
High Histological Entropy Is Correlated with Poor Overall Survival and Death Within the First 2 Years in Diffuse Large B-Cell Lymphoma.Cancers (Basel)202642512344PubTator, text miningPubMed
Oncogenesis as an Adverse Effect of Gene Replacement Therapy in Hematopoietic Stem Cells.Int J Mol Sci202642511445PubTator, text miningPubMed
Mtg16/Eto2 tumor suppressor maintains and establishes repression by distinct mechanisms.Mol Cell202642309063PubTator, text miningPubMed
Clinicopathological Characteristics and Prediction of Overall Survival and Death Within 2 Years in Diffuse Large B-Cell Lymphoma Based on Histological Images and Deep Learning.Biomedicines202642193459PubTator, text miningPubMed
Impact of aging on CD146+ mesenchymal stromal cells-mediated regulation of bone marrow CD34+ hematopoietic stem/progenitor cell mobilization.Front Bioeng Biotechnol202642183054PubTator, text miningPubMed

1 to 10 of 2,403

See all 2,403 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4005

GET https://conductscience.org/api/genes/v1/4005/patents?page=2