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LOX: lysyl oxidase

1 protein, 150 patents, 0 drugs, 0 trials, 4,887 NIH grants and 10,160 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolLOXHGNC
Namelysyl oxidaseHGNC
NCBI Gene ID4015NCBI Gene
HGNC IDHGNC:6664HGNC
EnsemblENSG00000113083NCBI Gene
AliasesAAT10NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P28300Protein-lysine 6-oxidase4170Ensembl, GeneID, HGNCUniProt

Patents 150

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452170P28300Espacenet
EP 4650780 A22025-11-1919295P28300Espacenet
EP 4650780 A22025-11-19786P28300Espacenet
EP 4640849 A22025-10-293922P28300Espacenet
EP 4640849 A22025-10-2995P28300Espacenet
EP 4641201 A22025-10-2924437P28300Espacenet
EP 4641201 A22025-10-29556P28300Espacenet
JP 2025147176 A2025-10-067945P28300Espacenet
JP 2025147176 A2025-10-067946P28300Espacenet
JP 2025529142 A2025-09-046909P28300Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 4887

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant302,025NIH's project files
P30CA008748Cancer Center Support Grant222,025NIH's project files
P30CA006973Regional Oncology Research Center142,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award112,025NIH's project files
K24AR060297Scleroderma Twin Study and analysis of Estrogen in patients with dcSSc102,025NIH's project files
P30CA023074University of Arizona Cancer Center - Cancer Center Support Grant92,025NIH's project files
P30CA060553The Robert H. Lurie Comprehensive Cancer Center92,025NIH's project files
P30DK050306Center for Molecular Studies in Digestive and Liver Diseases92,025NIH's project files
R01NS076511Lipid Imaging in Traumatic Brain Injury by High Resolution GCIB-secondary Ion Mass Spectrometry92,025NIH's project files
P30CA068485Cancer Center Support Grant82,025NIH's project files

Papers 10160

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42820787PubTator, text miningPubMed
42812889PubTator, text miningPubMed
42811626PubTator, text miningPubMed
42802716PubTator, text miningPubMed
42789583PubTator, text miningPubMed
42788414PubTator, text miningPubMed
42787770PubTator, text miningPubMed
42780753PubTator, text miningPubMed
42780667PubTator, text miningPubMed
42770147PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license