Gene · 4016
LOXL1: lysyl oxidase like 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LOXL1: lysyl oxidase like 1. Genes, record 4016. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4016
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q08397 | Lysyl oxidase homolog 1 | 574 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents60
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| EP 4650780 A2 | 2025-11-19 | 1988 | Q08397 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 240 | Q08397 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 1562 | Q08397 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 7948 | Q08397 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6910 | Q08397 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6910 | Q08397 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 240 | Q08397 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 1562 | Q08397 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 1988 | Q08397 | Espacenet |
| US 12303614 B2 | 2025-05-20 | 5 | Q08397 | Espacenet |
1 to 10 of 60
See all 60 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants828
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LOXL1 papers | Newest fiscal year |
|---|---|---|---|
| R01EY020928 | Genetic and Environmental Risk Factors for Exfoliation Syndrome and Glaucoma | 24 | 2025 |
| P30EY014104 | P30 Core Grant for Vision Research | 14 | 2025 |
| P30EY005722 | Center Core Grant for Vision Research | 8 | 2025 |
| P30EY010572 | Ophthalmology Core Facility | 7 | 2025 |
| R01EY024942 | THE UBIQUITIN PATHWAY IN CORNEAL SCARRING | 5 | 2025 |
| R01EY019643 | Extracellular Matrix and Outflow Resistance | 4 | 2025 |
| R01EY022305 | NEIGHBORHOOD Consortium for POAG Genetics | 4 | 2025 |
| R01EY022359 | eNOS-Dependent Mechanoregulation of Intraocular Pressure | 4 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 3 | 2025 |
| P30EY014801 | Miami Center for Vision Research | 3 | 2025 |
1 to 10 of 828Source NIH's project files
See all 828 nih grantsPapers1,658
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Erratum: [Corrigendum] Lysyl oxidase-like-1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved. | Oncol Lett | 2026 | 42798885 | PubTator, text mining | PubMed |
| Exploratory Analysis of Glaucoma-Associated SNPs in a Colombian Cohort Highlights Potential Involvement of Oxidative, Vascular, and Neurodegenerative Pathways. | Genes (Basel) | 2026 | 42650112 | PubTator, text mining | PubMed |
Integrated Bulk and Spatial Proteomics of Castleman Disease: Molecular Signatures Across Subtypes and Compartmentalized Pathogenic Networks in Idiopathic Multicentric Castleman disease (iMCD)-Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Dysfunction, and Organomegaly (TAFRO). | Mod Pathol | 2026 | 42641686 | PubTator, text mining | PubMed |
| Clinicopathological features of LOXL1-expressing non-small cell lung cancer: relation to the extent of CD8+ T-cell infiltration. | Cancer Treat Res Commun | 2026 | 42641459 | PubTator, text mining | PubMed |
| A dual pronged approach to cancer immune exclusion: tumor-derived LAIR-1 simultaneously drives fibrosis and blocks immune recruitment in glioma. | Res Sq | 2026 | 42620371 | PubTator, text mining | PubMed |
| Spatially resolved transcriptomic profiling of myelofibrosis spleen reveals compartment specific niche programs. | Exp Hematol Oncol | 2026 | 42547896 | PubTator, text mining | PubMed |
| Membrane proteomic profiling to identify candidate therapy targets for glioblastoma infiltration. | Neurooncol Adv | 2026 | 42534387 | PubTator, text mining | PubMed |
| Late-Onset Preeclampsia Is Linked to Extensive Remodeling of the Placental Extracellular Matrix. | Med Sci (Basel) | 2026 | 42506333 | PubTator, text mining | PubMed |
| LOXL1, THY1, and TYMS define an annotation-derived hemoglobin-associated immunotranscriptomic signature in osteoarthritis cartilage. | Front Immunol | 2026 | 42495609 | PubTator, text mining | PubMed |
| Network-informed multi-trait genomic analysis decodes the shared genetic architecture and therapeutic landscape of pelvic floor disorders. | NPJ Aging | 2026 | 42297840 | PubTator, text mining | PubMed |
1 to 10 of 1,658
See all 1,658 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4016
GET https://conductscience.org/api/genes/v1/4016/patents?page=2