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Gene · 4016

LOXL1: lysyl oxidase like 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LOXL1: lysyl oxidase like 1. Genes, record 4016. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4016

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Gene

Symbol
LOXL1
HGNC
Name
lysyl oxidase like 1
HGNC
NCBI Gene ID
4016
NCBI Gene
HGNC ID
HGNC:6665
HGNC
Ensembl
ENSG00000129038
NCBI Gene
Aliases
LOL, LOXL
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q08397Lysyl oxidase homolog 15740Ensembl, GeneID, HGNC

Source UniProt

Patents60

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4650780 A22025-11-191988Q08397Espacenet
EP 4640849 A22025-10-29240Q08397Espacenet
EP 4641201 A22025-10-291562Q08397Espacenet
JP 2025147176 A2025-10-067948Q08397Espacenet
JP 2025529142 A2025-09-046910Q08397Espacenet
US 12371689 B22025-07-296910Q08397Espacenet
JP 2025519096 A2025-06-24240Q08397Espacenet
JP 2025517969 A2025-06-121562Q08397Espacenet
JP 2025517970 A2025-06-121988Q08397Espacenet
US 12303614 B22025-05-205Q08397Espacenet

1 to 10 of 60

See all 60 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants828

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLOXL1 papersNewest fiscal year
R01EY020928Genetic and Environmental Risk Factors for Exfoliation Syndrome and Glaucoma242025
P30EY014104P30 Core Grant for Vision Research142025
P30EY005722Center Core Grant for Vision Research82025
P30EY010572Ophthalmology Core Facility72025
R01EY024942THE UBIQUITIN PATHWAY IN CORNEAL SCARRING52025
R01EY019643Extracellular Matrix and Outflow Resistance42025
R01EY022305NEIGHBORHOOD Consortium for POAG Genetics42025
R01EY022359eNOS-Dependent Mechanoregulation of Intraocular Pressure42025
P30CA006973Regional Oncology Research Center32025
P30EY014801Miami Center for Vision Research32025

1 to 10 of 828Source NIH's project files

See all 828 nih grants

Papers1,658

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Erratum: [Corrigendum] Lysyl oxidase-like-1 enhances lung metastasis when lactate accumulation and monocarboxylate transporter expression are involved.Oncol Lett202642798885PubTator, text miningPubMed
Exploratory Analysis of Glaucoma-Associated SNPs in a Colombian Cohort Highlights Potential Involvement of Oxidative, Vascular, and Neurodegenerative Pathways.Genes (Basel)202642650112PubTator, text miningPubMed
Integrated Bulk and Spatial Proteomics of Castleman Disease: Molecular Signatures Across Subtypes and Compartmentalized Pathogenic Networks in Idiopathic Multicentric Castleman disease (iMCD)-Thrombocytopenia, Anasarca, Fever, Reticulin Fibrosis/Renal Dysfunction, and Organomegaly (TAFRO).
Mod Pathol202642641686PubTator, text miningPubMed
Clinicopathological features of LOXL1-expressing non-small cell lung cancer: relation to the extent of CD8+ T-cell infiltration.Cancer Treat Res Commun202642641459PubTator, text miningPubMed
A dual pronged approach to cancer immune exclusion: tumor-derived LAIR-1 simultaneously drives fibrosis and blocks immune recruitment in glioma.Res Sq202642620371PubTator, text miningPubMed
Spatially resolved transcriptomic profiling of myelofibrosis spleen reveals compartment specific niche programs.Exp Hematol Oncol202642547896PubTator, text miningPubMed
Membrane proteomic profiling to identify candidate therapy targets for glioblastoma infiltration.Neurooncol Adv202642534387PubTator, text miningPubMed
Late-Onset Preeclampsia Is Linked to Extensive Remodeling of the Placental Extracellular Matrix.Med Sci (Basel)202642506333PubTator, text miningPubMed
LOXL1, THY1, and TYMS define an annotation-derived hemoglobin-associated immunotranscriptomic signature in osteoarthritis cartilage.Front Immunol202642495609PubTator, text miningPubMed
Network-informed multi-trait genomic analysis decodes the shared genetic architecture and therapeutic landscape of pelvic floor disorders.NPJ Aging202642297840PubTator, text miningPubMed

1 to 10 of 1,658

See all 1,658 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

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The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4016

GET https://conductscience.org/api/genes/v1/4016/patents?page=2