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LOXL2: lysyl oxidase like 2
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Gene · 4017

Papers2,536

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

1 to 20 of 2,536

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TitleJournalYearPMIDFound bySource
Spatial evolution of a cachexia-promoting microenvironment in pancreatic cancer.Cell202642810340PubTator, text miningPubMed
Cuproplasia-associated LOXL2 cooperates with Helicobacter pylori infection to promote gastric cancer progression via the FAK/Src signaling axis.J Gastrointest Oncol202642703334PubTator, text miningPubMed
Mechanistic insights into Strontium-90 superficial radiotherapy in keloids: senescence-associated changes and ECM remodeling across cell-matrix scales.Front Pharmacol202642688921PubTator, text miningPubMed
Lysine Oxidation by LOXL2 in Single Strands Versus Triple Helices: Implications for Collagen-Related Diseases.Angew Chem Int Ed Engl202642665990PubTator, text miningPubMed
Liver reprogramming toward hepatocellular carcinoma following hepatitis C sustained virologic response: a narrative review.Transl Gastroenterol Hepatol202642592470PubTator, text miningPubMed
Dual-Metal Regulation of Cardiac Remodeling: Targeting the LOXL2-Ferroptosis Axis in Metal-Induced Cardiac Dysfunction.Cardiovasc Toxicol202642536278PubTator, text miningPubMed
Histology-derived prediction of a stromal remodeling program in pancreatic ductal adenocarcinoma with transcriptomic and spatial validation.Transl Oncol202642526385PubTator, text miningPubMed
LOXL 2 Promotes the Epithelial-Mesenchymal Transition and Malignant Progression of Cervical Cancer [Retraction].Onco Targets Ther202642459201PubTator, text miningPubMed
Distinct Molecular Signature of Earlobe Keloids: Integrated Transcriptomic Analysis of Extracellualr Matrix, Metalloproteinase, and Metabolic Pathways.Aesthetic Plast Surg202642414644PubTator, text miningPubMed
The Matrix Reloaded: The Hepatic Matrisome as a Therapeutic Opportunity to Fight Liver Fibrosis.Biomolecules202642352350PubTator, text miningPubMed
Single-cell profiling reveals a novel CAF subpopulation linking stromal heterogeneity to immune suppression in breast cancer subtypes.J Transl Med202642351142PubTator, text miningPubMed
Integrative single-cell and bulk transcriptomics reveal cuproptosis subtypes, prognostic models, and COL5A1 as a key gene in glioblastoma.Cell Signal202642331202PubTator, text miningPubMed
Targeting the Tumor Extracellular Matrix: A New Frontier in Cancer Therapy.Curr Cancer Drug Targets202642316500PubTator, text miningPubMed
Design, synthesis, and evaluation of 4-(aminomethyl)-2-(phenylamino)pyridine derivatives as novel lysyl oxidase-like 2 inhibitors against metastatic melanoma.Bioorg Med Chem202642241910PubTator, text miningPubMed
Cell type-resolved analysis identifies LOXL2⁺ fibroblasts as key drivers of malignant stromal remodeling in hepatocellular carcinoma.Discov Oncol202642218344PubTator, text miningPubMed
Antibiotic-Loaded Polymethyl Methacrylate Cement Drives Fibroblast-Mediated Angiogenesis via LOXL2 to Accelerate Diabetic Foot Ulcer Healing.FASEB J202642213591PubTator, text miningPubMed
From Virtual Screening to Cell Phenotype: 4-Thiazolidone Scaffolds Targeting LOXL2 in Breast Cancer.Chem Biol Drug Des202642206657PubTator, text miningPubMed
METTL3-m6A-LOXL2 Axis Post-Transcriptionally Fine-Tunes Macrophage Migration and Invasion.Curr Med Sci202642201485PubTator, text miningPubMed
Targeting Lysyl Oxidase-like 2: A Therapeutic Strategy for Idiopathic Pulmonary Fibrosis with a Novel Indolizine Derivative.Pharmaceutics202642198248PubTator, text miningPubMed
Catestatin peptide impedes melanoma progression and drug resistance by reprogramming oncogenic signaling pathways.Oncogenesis202642168158PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

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  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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