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Gene · 403

ARL3: ARF like GTPase 3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARL3: ARF like GTPase 3. Genes, record 403. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/403

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Gene

Symbol
ARL3
HGNC
Name
ARF like GTPase 3
HGNC
NCBI Gene ID
403
NCBI Gene
HGNC ID
HGNC:694
HGNC
Ensembl
ENSG00000138175
NCBI Gene
Aliases
ARFL3, JBTS35, RP83
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P36405ADP-ribosylation factor-like protein 31820Ensembl, GeneID, HGNC

Source UniProt

Patents32

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026515744 A2026-05-19185P36405Espacenet
JP 2026004568 A2026-01-1436801P36405Espacenet
EP 4650780 A22025-11-191822P36405Espacenet
JP 2025517970 A2025-06-121822P36405Espacenet
JP 2025062604 A2025-04-143371P36405Espacenet
WO 2024214081 A12024-10-17185P36405Espacenet
US 11446398 B22022-09-203371P36405Espacenet
JP 2022524081 A2022-04-27106342P36405Espacenet
US 11078247 B22021-08-03768P36405Espacenet
JP 2019054813 A2019-04-11217236P36405Espacenet

1 to 10 of 32

See all 32 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants486

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARL3 papersNewest fiscal year
P30EY014800University of Utah Core Vision Research Grant82025
P30DK084567Mayo Center for Cell Signaling in Gastroenterology52025
T32NS096050Training In Systems And Integrative Biology Neuroscience42025
P30CA015083Mayo Clinic Comprehensive Cancer Center Support Grant22025
P30EY005722Center Core Grant for Vision Research22025
P30EY007003University of Michigan Vision Research Center22025
P30EY025585NEI Center Core Grant for Vision Research22025
R01CA268179Functional interplay between Hippo and estrogen receptor ESR122025
R01DK099160Molecular dissection of the ciliary gate22025
R01DK106404Obesity in ciliopathies: How neuronal primary cilia control appetite22025

1 to 10 of 486Source NIH's project files

See all 486 nih grants

Papers502

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Characterizing the impact of plasma protein levels on human brain structure and disorders leveraging integrative multi-omics analysis.medRxiv202642528609PubTator, text miningPubMed
Dual Roles of Ubiquitin-Specific Peptidase 10 (USP10) in Cancer.Cells202641892309PubTator, text miningPubMed
A Novel Heterozygous ARL3 Variant in Non-Syndromic Retinitis Pigmentosa: Clinical and Functional Characterization.Int J Mol Sci202641828587PubTator, text miningPubMed
Organoids for disease modeling and treatment: state-of-the-art.Exp Hematol Oncol202641545895PubTator, text miningPubMed
Emerging roles of the ciliary-mitochondrial axis in cellular homeostasis and neuroprotection.Mol Neurodegener Adv202542751568PubTator, text miningPubMed
ARL3 Enhances ERα Stability via USP10 Deubiquitination to Promote Endocrine Resistance and Drive Mitochondrial Metabolic Reprogramming in HR+ Breast Cancer.Adv Sci (Weinh)202541047477PubTator, text miningPubMed
Molecular basis for the activation of outer dynein arms in cilia.Nat Struct Mol Biol202541023246PubTator, text miningPubMed
A conserved mechanism for the retrieval of polyubiquitinated proteins from cilia.Cell202540840444PubTator, text miningPubMed
Spatial regulation of ARL3 and GSF-mediated lipidated cargo trafficking in the primary cilium.FEBS Lett202540836900PubTator, text miningPubMed
Photoaffinity enabled transcriptome-wide identification of splice modulating small molecule-RNA binding events in native cells.RSC Chem Biol202540226337PubTator, text miningPubMed

1 to 10 of 502

See all 502 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/403

GET https://conductscience.org/api/genes/v1/403/patents?page=2