Gene · 4036
LRP2: LDL receptor related protein 2
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LRP2: LDL receptor related protein 2. Genes, record 4036. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4036
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P98164 | Low-density lipoprotein receptor-related protein 2 | 4,655 | 4 | Ensembl, GeneID, HGNC |
Source UniProt
Patents67
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 51917 | P98164 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19554 | P98164 | Espacenet |
| EP 4640849 A2 | 2025-10-29 | 4048 | P98164 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 25220 | P98164 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8016 | P98164 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 2437 | P98164 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6924 | P98164 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 2437 | P98164 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6924 | P98164 | Espacenet |
| JP 2025519096 A | 2025-06-24 | 4048 | P98164 | Espacenet |
1 to 10 of 67
See all 67 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,425
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LRP2 papers | Newest fiscal year |
|---|---|---|---|
| ZIACP010195 | Alpha-Tocopherol, Beta-Carotene Cancer Prevention (ATBC) Study | 7 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 6 | 2025 |
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 6 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 6 | 2025 |
| P01HL116263 | HDL Function in Human Disease | 5 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 5 | 2025 |
| R01DK039773 | Mechanisms of Ischemic Kidney Injury and Repair | 5 | 2025 |
| R01DK072381 | Kidney Injury Molecule-1 in Epithelial Repair | 5 | 2025 |
| R01DK067299 | Novel Roles and Mechanisms of Proximal Tubule Mitochondrial Angiotensin II and Sirtuin 3 in Hypertension | 4 | 2025 |
1 to 10 of 2,425Source NIH's project files
See all 2,425 nih grantsPapers3,623
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A new beating heart model of cardiopulmonary bypass-induced acute kidney injury demonstrates heme protein toxicity and ferroptosis. | Am J Nephrol | 2026 | 42809521 | PubTator, text mining | PubMed |
| SCTR-Expressing Astrocyte-Serotonergic Neuron Signaling Drives Sexual Dimorphism in Depression Through KAT7/H4ac-Foxc2 Epigenetic Axis in an AMPK-Dependent Manner. | Adv Sci (Weinh) | 2026 | 42801528 | PubTator, text mining | PubMed |
| LRP2: A proteogenomics pipeline for long-read informed protein isoform analysis and discovery. | bioRxiv | 2026 | 42779594 | PubTator, text mining | PubMed |
| Kidney organoids as a platform to study plasminogen-induced injury and uPA-based therapies. | Stem Cells Transl Med | 2026 | 42768826 | PubTator, text mining | PubMed |
| Computational prioritization of megalin-aminoglycoside recognition and gentamicin-associated cellular stress responses. | Arch Biochem Biophys | 2026 | 42762957 | PubTator, text mining | PubMed |
| Molecular characterization of normal and physiologically suppressed human parathyroid glands at single-cell resolution. | J Endocr Soc | 2026 | 42761548 | PubTator, text mining | PubMed |
| Megalin: from structure to function. | Nat Rev Nephrol | 2026 | 42760389 | PubTator, text mining | PubMed |
| LINC00460 drives clear cell renal cell carcinoma progression via complement/coagulation and p53 pathways: a potential therapeutic target. | Am J Transl Res | 2026 | 42630874 | PubTator, text mining | PubMed |
| COPI Coatomer Regulates Several Steps of HDL Metabolism. | Arterioscler Thromb Vasc Biol | 2026 | 42592650 | PubTator, text mining | PubMed |
| Unveiling differential gene expression and pathways in clear cell renal cell carcinoma with sarcomatoid transformation. | PeerJ | 2026 | 42569572 | PubTator, text mining | PubMed |
1 to 10 of 3,623
See all 3,623 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4036
GET https://conductscience.org/api/genes/v1/4036/patents?page=2