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Gene · 4041

LRP5: LDL receptor related protein 5

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. LRP5: LDL receptor related protein 5. Genes, record 4041. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/4041

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
LRP5
HGNC
Name
LDL receptor related protein 5
HGNC
NCBI Gene ID
4041
NCBI Gene
HGNC ID
HGNC:6697
HGNC
Ensembl
ENSG00000162337
NCBI Gene
Aliases
BMND1, EVR1, EVR4, HBM, LR3, LRP-5, LRP-7, LRP7, OPPG, OPS, OPTA1, PCLD4, VBCH2
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O75197Low-density lipoprotein receptor-related protein 51,6150Ensembl, GeneID, HGNC

Source UniProt

Patents86

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
WO 2026219982 A12026-10-223O75197Espacenet
WO 2026219984 A12026-10-223O75197Espacenet
WO 2026219985 A12026-10-223O75197Espacenet
WO 2026219987 A12026-10-223O75197Espacenet
WO 2026219989 A12026-10-223O75197Espacenet
WO 2026220051 A12026-10-223O75197Espacenet
JP 2026515744 A2026-05-19200O75197Espacenet
JP 2026004568 A2026-01-1451923O75197Espacenet
EP 4650780 A22025-11-193564O75197Espacenet
EP 4640849 A22025-10-29456O75197Espacenet

1 to 10 of 86

See all 86 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,483

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
R01AR053237Lrp5 and Lrp6 signaling in bone mechanotransduction and metabolism292025
R01AR041398Novel Molecular Biomarkers of Bone Microarchitecture152025
P30CA016672Cancer Center Support Grant142025
I01BX001478Harnessing the anabolic potential of Wnt signaling to improve bone health122025
P30CA008748Cancer Center Support Grant102025
P30DK058404Molecular and Cellular Basis for Digestive Diseases82025
P30CA062203Cancer Center Support Grant72025
U19AG055373Trans-omics Integration of Multi-omics Studies for Osteoporosis72025
P01AG032959Bone as a Target and a Regulator of Aging62025
P20GM109036Tulane COBRE for Clinical and Translational Research in Cardiometabolic Diseases62025

1 to 10 of 2,483Source NIH's project files

See all 2,483 nih grants

Papers4,573

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42804492PubTator, text miningPubMed
42797047PubTator, text miningPubMed
42784573PubTator, text miningPubMed
42751639PubTator, text miningPubMed
42661774PubTator, text miningPubMed
42635748PubTator, text miningPubMed
42588292PubTator, text miningPubMed
42582263PubTator, text miningPubMed
42413667PubTator, text miningPubMed
42316479PubTator, text miningPubMed

1 to 10 of 4,573

See all 4,573 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4041

GET https://conductscience.org/api/genes/v1/4041/patents?page=2