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Gene · 4043

LRPAP1: LDL receptor related protein associated protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LRPAP1: LDL receptor related protein associated protein 1. Genes, record 4043. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4043

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Gene

Symbol
LRPAP1
HGNC
Name
LDL receptor related protein associated protein 1
HGNC
NCBI Gene ID
4043
NCBI Gene
HGNC ID
HGNC:6701
HGNC
Ensembl
ENSG00000163956
NCBI Gene
Aliases
A2MRAP, A2RAP, Alpha-2-MRAP, HBP44, MYP23, RAP, alpha-2-MRAP
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P30533Alpha-2-macroglobulin receptor-associated protein35710Ensembl, GeneID, HGNC

Source UniProt

Patents115

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1451930P30533Espacenet
EP 4650780 A22025-11-1919611P30533Espacenet
JP 2025147176 A2025-10-068020P30533Espacenet
JP 2025529142 A2025-09-046926P30533Espacenet
US 12371689 B22025-07-296926P30533Espacenet
JP 2025517970 A2025-06-1219611P30533Espacenet
WO 2025072672 A22025-04-037P30533Espacenet
JP 2025032204 A2025-03-1130987P30533Espacenet
JP 2025028160 A2025-02-288020P30533Espacenet
EP 4499712 A22025-02-052P30533Espacenet

1 to 10 of 115

See all 115 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,113

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLRPAP1 papersNewest fiscal year
P30CA016672Cancer Center Support Grant92025
R01MH071316Rac-GEF signaling in dendritic spines92025
R01HL056051Fibrin(ogen) Structure and Interactions72025
P01AI091580Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR52025
P30CA008748Cancer Center Support Grant52025
R35GM118177Excitable Networks in Directed Cell Migration52025
T32HL007698Interdisciplinary Training Program in Cardiovascular Disease52025
P30CA016086Cancer Center Support Grant42025
R01HG010169Sequence resolution of complex human genome structural variation42025
R01NS092735Plexin-B2 Function in Glioma Invasion42025

1 to 10 of 2,113Source NIH's project files

See all 2,113 nih grants

Papers2,811

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Genetic Determinants of Vascular Dementia: Blood Metabolite Associations and Candidate Therapeutic Target Prioritization.Genet Epidemiol202642808807PubTator, text miningPubMed
RAP-RNA: A Methodological Approach to Study Base-Pairing Between Endogenous RNAs.Methods Mol Biol202642681520PubTator, text miningPubMed
Mapping subcellular microenvironments using oligonucleotide-directed proximity labeling.Curr Opin Chem Biol202642612587PubTator, text miningPubMed
Correction to: Development of a clinical tool to identify patients with early inflammatory arthritis at high risk of employment loss: analysis from the National Early Inflammatory Arthritis Audit.Rheumatol Adv Pract202642583668PubTator, text miningPubMed
Investigation on Fatigue Damage Characteristics of Basalt Fiber-Reinforced Asphalt Mixtures with High RAP Content.Materials (Basel)202642513794PubTator, text miningPubMed
High-Throughput Screening Identifies Small-Molecule Inhibitors of the Tau-LRP1 Interaction.bioRxiv202642395472PubTator, text miningPubMed
Correction to: OA20 A case of rapidly progressive interstitial lung disease in anti-Ro52 positive amyopathic dermatomyositis.Rheumatol Adv Pract202642376630PubTator, text miningPubMed
Comprehensive analysis of the RBP regulome reveals functional modules and drug candidates in liver cancer.Sci Rep202642362666PubTator, text miningPubMed
A de novo Loss-of-function Variant in RAPGEF6 Supports its Role in Neuropsychiatric Disorders.J Mol Neurosci202642274819PubTator, text miningPubMed
Dynamical proteomic signatures for depression across preclinical stages in 52,121 individuals from a prospective cohort study.World J Biol Psychiatry202642246212PubTator, text miningPubMed

1 to 10 of 2,811

See all 2,811 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4043

GET https://conductscience.org/api/genes/v1/4043/patents?page=2