Gene · 4043
LRPAP1: LDL receptor related protein associated protein 1
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LRPAP1: LDL receptor related protein associated protein 1. Genes, record 4043. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4043
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P30533 | Alpha-2-macroglobulin receptor-associated protein | 357 | 10 | Ensembl, GeneID, HGNC |
Source UniProt
Patents115
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 51930 | P30533 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 19611 | P30533 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8020 | P30533 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6926 | P30533 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6926 | P30533 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 19611 | P30533 | Espacenet |
| WO 2025072672 A2 | 2025-04-03 | 7 | P30533 | Espacenet |
| JP 2025032204 A | 2025-03-11 | 30987 | P30533 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 8020 | P30533 | Espacenet |
| EP 4499712 A2 | 2025-02-05 | 2 | P30533 | Espacenet |
1 to 10 of 115
See all 115 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,113
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LRPAP1 papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 9 | 2025 |
| R01MH071316 | Rac-GEF signaling in dendritic spines | 9 | 2025 |
| R01HL056051 | Fibrin(ogen) Structure and Interactions | 7 | 2025 |
| P01AI091580 | Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR | 5 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 5 | 2025 |
| R35GM118177 | Excitable Networks in Directed Cell Migration | 5 | 2025 |
| T32HL007698 | Interdisciplinary Training Program in Cardiovascular Disease | 5 | 2025 |
| P30CA016086 | Cancer Center Support Grant | 4 | 2025 |
| R01HG010169 | Sequence resolution of complex human genome structural variation | 4 | 2025 |
| R01NS092735 | Plexin-B2 Function in Glioma Invasion | 4 | 2025 |
1 to 10 of 2,113Source NIH's project files
See all 2,113 nih grantsPapers2,811
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Genetic Determinants of Vascular Dementia: Blood Metabolite Associations and Candidate Therapeutic Target Prioritization. | Genet Epidemiol | 2026 | 42808807 | PubTator, text mining | PubMed |
| RAP-RNA: A Methodological Approach to Study Base-Pairing Between Endogenous RNAs. | Methods Mol Biol | 2026 | 42681520 | PubTator, text mining | PubMed |
| Mapping subcellular microenvironments using oligonucleotide-directed proximity labeling. | Curr Opin Chem Biol | 2026 | 42612587 | PubTator, text mining | PubMed |
| Correction to: Development of a clinical tool to identify patients with early inflammatory arthritis at high risk of employment loss: analysis from the National Early Inflammatory Arthritis Audit. | Rheumatol Adv Pract | 2026 | 42583668 | PubTator, text mining | PubMed |
| Investigation on Fatigue Damage Characteristics of Basalt Fiber-Reinforced Asphalt Mixtures with High RAP Content. | Materials (Basel) | 2026 | 42513794 | PubTator, text mining | PubMed |
| High-Throughput Screening Identifies Small-Molecule Inhibitors of the Tau-LRP1 Interaction. | bioRxiv | 2026 | 42395472 | PubTator, text mining | PubMed |
| Correction to: OA20 A case of rapidly progressive interstitial lung disease in anti-Ro52 positive amyopathic dermatomyositis. | Rheumatol Adv Pract | 2026 | 42376630 | PubTator, text mining | PubMed |
| Comprehensive analysis of the RBP regulome reveals functional modules and drug candidates in liver cancer. | Sci Rep | 2026 | 42362666 | PubTator, text mining | PubMed |
| A de novo Loss-of-function Variant in RAPGEF6 Supports its Role in Neuropsychiatric Disorders. | J Mol Neurosci | 2026 | 42274819 | PubTator, text mining | PubMed |
| Dynamical proteomic signatures for depression across preclinical stages in 52,121 individuals from a prospective cohort study. | World J Biol Psychiatry | 2026 | 42246212 | PubTator, text mining | PubMed |
1 to 10 of 2,811
See all 2,811 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4043
GET https://conductscience.org/api/genes/v1/4043/patents?page=2