Gene · 4060
LUM: lumican
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. LUM: lumican. Genes, record 4060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4060
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P51884 | Lumican | 338 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents105
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026510738 A | 2026-04-10 | 10 | P51884 | Espacenet |
| JP 2026042028 A | 2026-03-10 | 55 | P51884 | Espacenet |
| EP 4676555 A1 | 2026-01-14 | 10 | P51884 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 51968 | P51884 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 2585 | P51884 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 8153 | P51884 | Espacenet |
| JP 2025529142 A | 2025-09-04 | 6947 | P51884 | Espacenet |
| US 12371689 B2 | 2025-07-29 | 6947 | P51884 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 2585 | P51884 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 8153 | P51884 | Espacenet |
1 to 10 of 105
See all 105 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants2,305
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | LUM papers | Newest fiscal year |
|---|---|---|---|
| P30EY008098 | Core Grant for Vision Research | 18 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 12 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 9 | 2025 |
| R01EY026104 | Cellular and Genetic Defects in Keratoconus | 8 | 2025 |
| P30EY003790 | Core Grant for Vision Research | 7 | 2025 |
| R01EY005665 | Corneal Epithelial-Stromal Interactions During Regeneration and Fibrosis | 7 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 7 | 2025 |
| P30AG028716 | Duke Claude D. Pepper Older Americans Independence Center | 5 | 2025 |
| P30CA047904 | Cancer Center Support Grant | 5 | 2025 |
| R01HL134817 | Causal variant association mechanisms in TCF21 binding coronary disease loci | 5 | 2025 |
1 to 10 of 2,305Source NIH's project files
See all 2,305 nih grantsPapers3,622
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| A bioactivity-enhanced thermosensitive amnion-derived hydrogel with sustained IGF-1 release: A multitargeted and efficient strategy for corneal injury repair. | Bioact Mater | 2027 | 42781431 | PubTator, text mining | PubMed |
| Exploring Molecular Pathways in Metastasis of Breast Cancer Cells to the Brain: Insights from Gene Expression Analysis and Cellular Origins. | J Microsc Ultrastruct | 2026 | 42824931 | PubTator, text mining | PubMed |
| Extracellular matrix proteoglycans lumican and biglycan promote innate immune signals and viral clearance in HSV-1 infections of mouse corneas. | bioRxiv | 2026 | 42780025 | PubTator, text mining | PubMed |
| Clinical and Proteomic Biomarkers of Trifluridine/Tipiracil in Fluoropyrimidine-Refractory Advanced Pancreatic Adenocarcinoma: A Single-Arm Phase II Trial. | JCO Precis Oncol | 2026 | 42777178 | PubTator, text mining | PubMed |
| Characterization of LOV domain-ribityllumazine complex with blue-shifted fluorescence. | Biochem Biophys Res Commun | 2026 | 42743751 | PubTator, text mining | PubMed |
| Twist1 Promotes Endothelial Phenotypic Transition and Unstable Plaque Phenotype During Atherosclerosis. | Arterioscler Thromb Vasc Biol | 2026 | 42689320 | PubTator, text mining | PubMed |
| Spatial transcriptomics reveals injury-responsive compartments and coordinated immune-fibrotic signaling in ANCA-associated renal vasculitis. | Front Immunol | 2026 | 42602048 | PubTator, text mining | PubMed |
| Systems-level identification of conserved molecular drivers underlying the progression of alcoholic hepatitis and alcoholic cirrhosis and their therapeutic modulation by S-adenosyl-L-methionine. | Front Bioinform | 2026 | 42528928 | PubTator, text mining | PubMed |
| Single-cell sequencing combined with transcriptome analysis unravels LUM+ B cells as key drivers in abdominal aortic aneurysm. | Front Immunol | 2026 | 42459700 | PubTator, text mining | PubMed |
| Transcriptomic Identification of Diagnostic Biomarkers for Alcohol-Associated Liver Cirrhosis: Integration of Population-Level Epidemiology with Multi-Cohort Transcriptomic Analysis. | Int J Mol Sci | 2026 | 42450082 | PubTator, text mining | PubMed |
1 to 10 of 3,622
See all 3,622 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4060
GET https://conductscience.org/api/genes/v1/4060/patents?page=2