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Gene · 4060

LUM: lumican

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. LUM: lumican. Genes, record 4060. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4060

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Gene

Symbol
LUM
HGNC
Name
lumican
HGNC
NCBI Gene ID
4060
NCBI Gene
HGNC ID
HGNC:6724
HGNC
Ensembl
ENSG00000139329
NCBI Gene
Aliases
LDC, SLRR2D
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P51884Lumican3380Ensembl, GeneID, HGNC

Source UniProt

Patents105

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026510738 A2026-04-1010P51884Espacenet
JP 2026042028 A2026-03-1055P51884Espacenet
EP 4676555 A12026-01-1410P51884Espacenet
JP 2026004568 A2026-01-1451968P51884Espacenet
EP 4650780 A22025-11-192585P51884Espacenet
JP 2025147176 A2025-10-068153P51884Espacenet
JP 2025529142 A2025-09-046947P51884Espacenet
US 12371689 B22025-07-296947P51884Espacenet
JP 2025517970 A2025-06-122585P51884Espacenet
JP 2025028160 A2025-02-288153P51884Espacenet

1 to 10 of 105

See all 105 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,305

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleLUM papersNewest fiscal year
P30EY008098Core Grant for Vision Research182025
P30CA016672Cancer Center Support Grant122025
P30CA008748Cancer Center Support Grant92025
R01EY026104Cellular and Genetic Defects in Keratoconus82025
P30EY003790Core Grant for Vision Research72025
R01EY005665Corneal Epithelial-Stromal Interactions During Regeneration and Fibrosis72025
UL1TR001863Yale Clinical and Translational Science Award72025
P30AG028716Duke Claude D. Pepper Older Americans Independence Center52025
P30CA047904Cancer Center Support Grant52025
R01HL134817Causal variant association mechanisms in TCF21 binding coronary disease loci52025

1 to 10 of 2,305Source NIH's project files

See all 2,305 nih grants

Papers3,622

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
A bioactivity-enhanced thermosensitive amnion-derived hydrogel with sustained IGF-1 release: A multitargeted and efficient strategy for corneal injury repair.Bioact Mater202742781431PubTator, text miningPubMed
Exploring Molecular Pathways in Metastasis of Breast Cancer Cells to the Brain: Insights from Gene Expression Analysis and Cellular Origins.J Microsc Ultrastruct202642824931PubTator, text miningPubMed
Extracellular matrix proteoglycans lumican and biglycan promote innate immune signals and viral clearance in HSV-1 infections of mouse corneas.bioRxiv202642780025PubTator, text miningPubMed
Clinical and Proteomic Biomarkers of Trifluridine/Tipiracil in Fluoropyrimidine-Refractory Advanced Pancreatic Adenocarcinoma: A Single-Arm Phase II Trial.JCO Precis Oncol202642777178PubTator, text miningPubMed
Characterization of LOV domain-ribityllumazine complex with blue-shifted fluorescence.Biochem Biophys Res Commun202642743751PubTator, text miningPubMed
Twist1 Promotes Endothelial Phenotypic Transition and Unstable Plaque Phenotype During Atherosclerosis.Arterioscler Thromb Vasc Biol202642689320PubTator, text miningPubMed
Spatial transcriptomics reveals injury-responsive compartments and coordinated immune-fibrotic signaling in ANCA-associated renal vasculitis.Front Immunol202642602048PubTator, text miningPubMed
Systems-level identification of conserved molecular drivers underlying the progression of alcoholic hepatitis and alcoholic cirrhosis and their therapeutic modulation by S-adenosyl-L-methionine.Front Bioinform202642528928PubTator, text miningPubMed
Single-cell sequencing combined with transcriptome analysis unravels LUM+ B cells as key drivers in abdominal aortic aneurysm.Front Immunol202642459700PubTator, text miningPubMed
Transcriptomic Identification of Diagnostic Biomarkers for Alcohol-Associated Liver Cirrhosis: Integration of Population-Level Epidemiology with Multi-Cohort Transcriptomic Analysis.Int J Mol Sci202642450082PubTator, text miningPubMed

1 to 10 of 3,622

See all 3,622 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4060

GET https://conductscience.org/api/genes/v1/4060/patents?page=2