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Gene · 4068

SH2D1A: SH2 domain containing 1A

11 sourcesgene-search-2026-11-11-0.1.0

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ConductScience Library. SH2D1A: SH2 domain containing 1A. Genes, record 4068. Release gene-search-2026-11-11-0.1.0, 11 Nov 2026. https://conductscience.org/library/genes/4068

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Gene

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

Symbol
SH2D1A
HGNC
Name
SH2 domain containing 1A
HGNC
NCBI Gene ID
4068
NCBI Gene
HGNC ID
HGNC:10820
HGNC
Ensembl
ENSG00000183918
NCBI Gene
Aliases
DSHP, EBVS, IMD5, LYP, MTCP1, SAP, SAP/SH2D1A, XLP, XLPD, XLPD1
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
O60880SH2 domain-containing protein 1A1286Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1463333O60880Espacenet
JP 2025032204 A2025-03-1135565O60880Espacenet
EP 4461818 A22024-11-1335565O60880Espacenet
JP 2023058610 A2023-04-2535565O60880Espacenet
US 11446398 B22022-09-2078480O60880Espacenet
JP 2022524081 A2022-04-27181451O60880Espacenet
KR 1020210125456 A2021-10-1821O60880Espacenet
US 11047010 B22021-06-293242O60880Espacenet
US 10865447 B22020-12-153242O60880Espacenet
JP 2020508652 A2020-03-2635565O60880Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants2,075

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal year
P30CA008748Cancer Center Support Grant112025
UL1TR001866Developing, Demonstrating, and Disseminating Innovative Programs to Achieve Translational Success112025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital102025
R01AI125640Novel mechanisms regulating PD-1 signaling and function92025
P30CA016672Cancer Center Support Grant82025
UL1TR001863Yale Clinical and Translational Science Award72025
ZIAAI000913Epstein-Barr Virus Associated Disorders72025
R37AR040072Immune Responses in Lupus52025
ZIAAI001222Characterization of the cellular and molecular bases of inborn errors of immunity52025
ZIAAI001265Host factors contributing to susceptibility to COVID-19 disease52025

1 to 10 of 2,075Source NIH's project files

See all 2,075 nih grants

Papers4,343

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42805341PubTator, text miningPubMed
42775443PubTator, text miningPubMed
42737820PubTator, text miningPubMed
42735775PubTator, text miningPubMed
42708741PubTator, text miningPubMed
42654963PubTator, text miningPubMed
42576069PubTator, text miningPubMed
42563154PubTator, text miningPubMed
42505289PubTator, text miningPubMed
42495637PubTator, text miningPubMed

1 to 10 of 4,343

See all 4,343 papers

Sources 11

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNone stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GeneNone named. Public domain as US government information
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4068

GET https://conductscience.org/api/genes/v1/4068/patents?page=2