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MIR21: microRNA 21

0 proteins, 0 patents, 2 drugs, 3 trials, 7,025 NIH grants and 30,541 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMIR21HGNC
NamemicroRNA 21HGNC
NCBI Gene ID406991NCBI Gene
HGNC IDHGNC:31586HGNC
EnsemblENSG00000284190NCBI Gene
AliasesMIR-21, MIRN21, hsa-mir-21, miR-21, miRNA21NCBI Gene
TypencRNANCBI Gene

Proteins 0

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource

Patents 0

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource

Drugs 2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
LADEMIRSENCHEMBL4298087microRNA 21 antisense inhibitorANTISENSE INHIBITORChEMBL
LADEMIRSEN SODIUMCHEMBL4297246microRNA 21 antisense inhibitorANTISENSE INHIBITORChEMBL

Trials 3

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03373786LADEMIRSEN SODIUMPHASE1ClinicalTrials.gov
NCT03373786LADEMIRSENPHASE1ClinicalTrials.gov
NCT02855268LADEMIRSENPHASE22023-10-23ClinicalTrials.gov

NIH grants 7025

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30CA016672Cancer Center Support Grant972,025NIH's project files
P30CA016058Cancer Center Support Grant652,025NIH's project files
P30CA008748Cancer Center Support Grant392,025NIH's project files
P30CA006973Regional Oncology Research Center222,025NIH's project files
P50CA127001SPORE in Brain Cancer212,025NIH's project files
P30CA033572Cancer Center Support Grant182,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award172,025NIH's project files
P30CA056036Translational Research in Cancer162,025NIH's project files
P30CA068485Cancer Center Support Grant132,025NIH's project files
P30DK084567Mayo Center for Cell Signaling in Gastroenterology132,025NIH's project files

Papers 30541

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42826621PubTator, text miningPubMed
42825909PubTator, text miningPubMed
42821019PubTator, text miningPubMed
42819772PubTator, text miningPubMed
42813570PubTator, text miningPubMed
42804630PubTator, text miningPubMed
42795645PubTator, text miningPubMed
42794756PubTator, text miningPubMed
42792647PubTator, text miningPubMed
42790080PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license