Gene · 4077
NBR1: NBR1 autophagy cargo receptor
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. NBR1: NBR1 autophagy cargo receptor. Genes, record 4077. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4077
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| Q14596 | Next to BRCA1 gene 1 protein | 966 | 8 | Ensembl, GeneID, HGNC |
Source UniProt
Patents40
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 55159 | Q14596 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 55162 | Q14596 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 6811 | Q14596 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 6612 | Q14596 | Espacenet |
| EP 4618968 A1 | 2025-09-24 | 39 | Q14596 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 6612 | Q14596 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 6811 | Q14596 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 55823 | Q14596 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 55826 | Q14596 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 158794 | Q14596 | Espacenet |
1 to 10 of 40
See all 40 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,011
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | NBR1 papers | Newest fiscal year |
|---|---|---|---|
| R01CA126792 | Autophagy and Pro-metastatic Differentiation | 15 | 2025 |
| R35GM131919 | The mechanism and regulation of autophagy | 7 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 6 | 2025 |
| T32CA009594 | Multi-Disciplinary Training Grant in Cancer Research | 6 | 2025 |
| P20GM113132 | The Institute for Biomolecular Targeting | 5 | 2025 |
| P30CA016520 | Abramson Cancer Center Support Grant | 5 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 5 | 2025 |
| P20GM121176 | Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2. | 4 | 2025 |
| P30CA023108 | Cancer Center Support Grant | 4 | 2025 |
| P30CA030199 | Cancer Center Support Grant (CCSG) | 4 | 2025 |
1 to 10 of 1,011Source NIH's project files
See all 1,011 nih grantsPapers1,702
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Selective Autophagy in Plant Immunity: Mechanisms, Regulation, and Emerging Concepts in Xenophagy. | Plant Cell Environ | 2026 | 42678042 | PubTator, text mining | PubMed |
| A B-box protein BReaks brassinosteroid regulation of photomorphogenesis in the dark and light. | Plant Physiol | 2026 | 42583792 | PubTator, text mining | PubMed |
| CcFTR54 suppresses SVCV replication by promoting NBR1-mediated autophagic degradation of P protein. | Fish Shellfish Immunol | 2026 | 42520948 | PubTator, text mining | PubMed |
| Autophagy in plants: molecular mechanisms and roles in abiotic stress responses. | Front Plant Sci | 2026 | 42394666 | PubTator, text mining | PubMed |
| Beyond autophagic flux: selective autophagy adaptors and cargo prioritization in cardiac disease. | Cardiol Plus | 2026 | 42369864 | PubTator, text mining | PubMed |
| Circadian gene CLOCK-mediated LLPS of NBR1 and p62/SQSTM1 inhibits proliferation and migration of nasopharyngeal carcinoma. | Cell Death Dis | 2026 | 42270580 | PubTator, text mining | PubMed |
| Integrated in vitro and bioinformatic analysis of autophagy‑related gene expression modulated by Fe₂O₃/Au core-shell nanoparticles in breast cancer cells. | BMC Cancer | 2026 | 42216165 | PubTator, text mining | PubMed |
| A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer. | Mol Cell | 2026 | 42214332 | PubTator, text mining | PubMed |
| NBR1-Mediated Selective Autophagy in Plant Development and Stress Responses. | Plants (Basel) | 2026 | 42122842 | PubTator, text mining | PubMed |
| Liver-originated selective autophagy of BTD by alectinib underlies concurrent hepatotoxicity and dermatotoxicity. | Autophagy | 2026 | 42107012 | PubTator, text mining | PubMed |
1 to 10 of 1,702
See all 1,702 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4077
GET https://conductscience.org/api/genes/v1/4077/patents?page=2