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Gene · 4077

NBR1: NBR1 autophagy cargo receptor

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. NBR1: NBR1 autophagy cargo receptor. Genes, record 4077. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4077

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Gene

Symbol
NBR1
HGNC
Name
NBR1 autophagy cargo receptor
HGNC
NCBI Gene ID
4077
NCBI Gene
HGNC ID
HGNC:6746
HGNC
Ensembl
ENSG00000188554
NCBI Gene
Aliases
1A1-3B, CA125, IAI3B, KIAA0049, M17S2, MIG19
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q14596Next to BRCA1 gene 1 protein9668Ensembl, GeneID, HGNC

Source UniProt

Patents40

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1455159Q14596Espacenet
JP 2026004568 A2026-01-1455162Q14596Espacenet
EP 4650780 A22025-11-196811Q14596Espacenet
EP 4641201 A22025-10-296612Q14596Espacenet
EP 4618968 A12025-09-2439Q14596Espacenet
JP 2025517969 A2025-06-126612Q14596Espacenet
JP 2025517970 A2025-06-126811Q14596Espacenet
US 11446398 B22022-09-2055823Q14596Espacenet
US 11446398 B22022-09-2055826Q14596Espacenet
JP 2022524081 A2022-04-27158794Q14596Espacenet

1 to 10 of 40

See all 40 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,011

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleNBR1 papersNewest fiscal year
R01CA126792Autophagy and Pro-metastatic Differentiation152025
R35GM131919The mechanism and regulation of autophagy72025
P30CA016672Cancer Center Support Grant62025
T32CA009594Multi-Disciplinary Training Grant in Cancer Research62025
P20GM113132The Institute for Biomolecular Targeting52025
P30CA016520Abramson Cancer Center Support Grant52025
R01AG011085Ubiquitin‐mediated proteolysis and cell cycle control52025
P20GM121176Autophagy, Inflammation and Metabolism (AIM) in Disease Center - Phase 2.42025
P30CA023108Cancer Center Support Grant42025
P30CA030199Cancer Center Support Grant (CCSG)42025

1 to 10 of 1,011Source NIH's project files

See all 1,011 nih grants

Papers1,702

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Selective Autophagy in Plant Immunity: Mechanisms, Regulation, and Emerging Concepts in Xenophagy.Plant Cell Environ202642678042PubTator, text miningPubMed
A B-box protein BReaks brassinosteroid regulation of photomorphogenesis in the dark and light.Plant Physiol202642583792PubTator, text miningPubMed
CcFTR54 suppresses SVCV replication by promoting NBR1-mediated autophagic degradation of P protein.Fish Shellfish Immunol202642520948PubTator, text miningPubMed
Autophagy in plants: molecular mechanisms and roles in abiotic stress responses.Front Plant Sci202642394666PubTator, text miningPubMed
Beyond autophagic flux: selective autophagy adaptors and cargo prioritization in cardiac disease.Cardiol Plus202642369864PubTator, text miningPubMed
Circadian gene CLOCK-mediated LLPS of NBR1 and p62/SQSTM1 inhibits proliferation and migration of nasopharyngeal carcinoma.Cell Death Dis202642270580PubTator, text miningPubMed
Integrated in vitro and bioinformatic analysis of autophagy‑related gene expression modulated by Fe₂O₃/Au core-shell nanoparticles in breast cancer cells.BMC Cancer202642216165PubTator, text miningPubMed
A multi-subunit autophagic capture complex facilitates degradation of ER-stalled MHC class I in pancreatic cancer.Mol Cell202642214332PubTator, text miningPubMed
NBR1-Mediated Selective Autophagy in Plant Development and Stress Responses.Plants (Basel)202642122842PubTator, text miningPubMed
Liver-originated selective autophagy of BTD by alectinib underlies concurrent hepatotoxicity and dermatotoxicity.Autophagy202642107012PubTator, text miningPubMed

1 to 10 of 1,702

See all 1,702 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4077

GET https://conductscience.org/api/genes/v1/4077/patents?page=2