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Gene · 4084

MXD1: MAX dimerization protein 1

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MXD1: MAX dimerization protein 1. Genes, record 4084. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4084

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Gene

Symbol
MXD1
HGNC
Name
MAX dimerization protein 1
HGNC
NCBI Gene ID
4084
NCBI Gene
HGNC ID
HGNC:6761
HGNC
Ensembl
ENSG00000059728
NCBI Gene
Aliases
BHLHC58, MAD, MAD1, bHLHc58
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
Q05195Max dimerization protein 12215Ensembl, GeneID, HGNC

Source UniProt

Patents45

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
EP 4641201 A22025-10-291928Q05195Espacenet
JP 2025147176 A2025-10-0615317Q05195Espacenet
JP 2025517969 A2025-06-121928Q05195Espacenet
JP 2025032204 A2025-03-1131911Q05195Espacenet
JP 2025028160 A2025-02-2815317Q05195Espacenet
KR 1020250010750 A2025-01-2115317Q05195Espacenet
EP 4461818 A22024-11-1331911Q05195Espacenet
JP 2024109657 A2024-08-1415156Q05195Espacenet
JP 2023058610 A2023-04-2531911Q05195Espacenet
US 11446398 B22022-09-2049524Q05195Espacenet

1 to 10 of 45

See all 45 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,780

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMXD1 papersNewest fiscal year
P30CA006927Comprehensive Cancer Center Program at Fox Chase142025
P30CA016672Cancer Center Support Grant142025
P30CA008748Cancer Center Support Grant132025
P30MH092177Comprehensive NeuroHIV Center122025
R01GM074215Kinetochore Specification and Function72025
P30CA021765Cancer Center Support Grant (CCSG)62025
P40OD010440Caenorhabditis Genetics Center62025
P20GM103423The Maine Biomedical Research Network (INBRE)52025
P30CA042014Cancer Center Support Grant52025
P30CA006973Regional Oncology Research Center42025

1 to 10 of 1,780Source NIH's project files

See all 1,780 nih grants

Papers2,767

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Computed tomography analysis of glenoid size and bone depth: insights for baseplate fixation in reverse shoulder arthroplasty.JSES Rev Rep Tech202642750994PubTator, text miningPubMed
Spindle Assembly Checkpoint Competency Determines Sensitivity to KIF18A Inhibition in Small Cell Lung Cancer.Cancer Res Commun202642647139PubTator, text miningPubMed
Spindle Assembly Checkpoint Competency Determines Sensitivity to KIF18A Inhibition in Small-Cell Lung Cancer.bioRxiv202642619900PubTator, text miningPubMed
Yorkie/YAP Interactors: Fine-Tuning the Hippo Pathway Output.Cold Spring Harb Perspect Biol202642575696PubTator, text miningPubMed
Exploring the potential involvement of UFSP2 in spindle assembly checkpoint regulation in breast cancer.Mol Biol Rep202642430000PubTator, text miningPubMed
hSpindly dynamics modulate spindle assembly checkpoint signaling, promoting resistance to mitotic inhibitors.iScience202642338480PubTator, text miningPubMed
Norlichexanthone, a shunt product of Griseofulvin, disrupts spindle assembly checkpoint and nucleocytoplasmic transport by targeting TPR in the nuclear pore complex.Bioorg Chem202642330849PubTator, text miningPubMed
Identification and analysis of diagnostic senescence-related gene signatures for acute myocardial infarction based on multi-omics data and machine learning.Front Immunol202642327787PubTator, text miningPubMed
Folate deficiency correlates with severity of primary biliary cholangitis via modulating key regulatory genes.Front Nutr202642317867PubTator, text miningPubMed
Membrane ATG8ylation in secretory autophagy.Autophagy202642178909PubTator, text miningPubMed

1 to 10 of 2,767

See all 2,767 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4084

GET https://conductscience.org/api/genes/v1/4084/patents?page=2