Gene · 4093
SMAD9: SMAD family member 9
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. SMAD9: SMAD family member 9. Genes, record 4093. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4093
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| O15198 | SMAD family member 9 | 467 | 1 | Ensembl, GeneID, HGNC |
Source UniProt
Patents36
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026027383 A | 2026-02-18 | 32 | O15198 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 63763 | O15198 | Espacenet |
| JP 2026004568 A | 2026-01-14 | 63764 | O15198 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 10223 | O15198 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 10525 | O15198 | Espacenet |
| JP 2025147176 A | 2025-10-06 | 15630 | O15198 | Espacenet |
| JP 2025094220 A | 2025-06-24 | 172 | O15198 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 10525 | O15198 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 10223 | O15198 | Espacenet |
| JP 2025028160 A | 2025-02-28 | 15630 | O15198 | Espacenet |
1 to 10 of 36
See all 36 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,262
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | SMAD9 papers | Newest fiscal year |
|---|---|---|---|
| P30CA008748 | Cancer Center Support Grant | 8 | 2025 |
| P30CA068485 | Cancer Center Support Grant | 8 | 2025 |
| P30CA016672 | Cancer Center Support Grant | 5 | 2025 |
| P30DK058404 | Molecular and Cellular Basis for Digestive Diseases | 5 | 2025 |
| R01AA023146 | Role of Beta Spectrin and Smad in Alcohol-Induced Liver and GI Cell Proliferation | 5 | 2025 |
| R01HL124021 | An endothelial-fibroblast axis connecting senescence to amino acid metabolism for control of vascular stiffness in PAH | 5 | 2025 |
| UL1TR001863 | Yale Clinical and Translational Science Award | 5 | 2025 |
| R01CA236591 | Cellular interactions between TGF-beta pathway members and epigenetic regulators in liver and gastrointestinal cancers | 4 | 2025 |
| R01HD032067 | Transforming growth factor β family signaling pathways in ovarian and uterine biology | 4 | 2025 |
| R01HL076246 | Chemokines in healing myocardial infarction | 4 | 2025 |
1 to 10 of 1,262Source NIH's project files
See all 1,262 nih grantsPapers2,192
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| From Germline Variants to Tumor Outcome: GWAS-Based Functional Genomics Prioritizes Colorectal Cancer Susceptibility Genes and Links SMAD9 to Prognosis. | Hum Mutat | 2026 | 42626603 | PubTator, text mining | PubMed |
| A Case of High Pressure and High Stakes: Pulmonary Arterial Hypertension Emergence in an Infant With Hereditary Hemorrhagic Telangiectasia. | Pulm Circ | 2026 | 42516693 | PubTator, text mining | PubMed |
| Molecular-Genetic Basis of Pulmonary Arterial Hypertension (PAH). | Curr Issues Mol Biol | 2026 | 42353577 | PubTator, text mining | PubMed |
| Expression pattern of SMAD8 in geese at different reproductive stages and its effect on reproductive physiology and egg production performance. | J Adv Vet Anim Res | 2026 | 42180270 | PubTator, text mining | PubMed |
| Phenotype-specific differences in bone morphogenetic protein ligand expression and intracellular signaling pathway activation in chronic rhinosinusitis. | Mol Biol Rep | 2026 | 42018047 | PubTator, text mining | PubMed |
| Future Prospects of Imatinib in Advanced Pulmonary Hypertension Management. | IUBMB Life | 2026 | 41885124 | PubTator, text mining | PubMed |
| RNA-seq at different stages of human pancreatic β cell differentiation reveals proliferation dynamics and SMAD9 in directing β cell fate. | Cell Death Dis | 2026 | 41807373 | PubTator, text mining | PubMed |
| Bone Morphogenetic Protein (BMP) 9 Outperforms BMP2 in Osteogenesis and Osseointegration: In Vitro and In Vivo. | Clin Implant Dent Relat Res | 2026 | 41806300 | PubTator, text mining | PubMed |
| Dose-optimized HILT promotes peripheral nerve repair through BMP4-Smad9-mediated inhibition of neuroinflammation and oxidative stress. | APL Bioeng | 2026 | 41799557 | PubTator, text mining | PubMed |
| Mandibular Cortical Thickness Predicts Skull BMD in Adolescents. | Calcif Tissue Int | 2026 | 41787089 | PubTator, text mining | PubMed |
1 to 10 of 2,192
See all 2,192 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4093
GET https://conductscience.org/api/genes/v1/4093/patents?page=2