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Gene · 410

ARSA: arylsulfatase A

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. ARSA: arylsulfatase A. Genes, record 410. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/410

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Gene

Symbol
ARSA
HGNC
Name
arylsulfatase A
HGNC
NCBI Gene ID
410
NCBI Gene
HGNC ID
HGNC:713
HGNC
Ensembl
ENSG00000100299
NCBI Gene
Aliases
ASA, MLD
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P15289Arylsulfatase A50710Ensembl, GeneID, HGNC

Source UniProt

Patents83

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026067851 A2026-04-21253P15289Espacenet
JP 2026004568 A2026-01-1437910P15289Espacenet
JP 2026004568 A2026-01-1437911P15289Espacenet
EP 4650780 A22025-11-1940482P15289Espacenet
US 12410415 B22025-09-091P15289Espacenet
JP 2025529142 A2025-09-045524P15289Espacenet
WO 2025157942 A22025-07-311P15289Espacenet
JP 2025111747 A2025-07-30152P15289Espacenet
US 12371689 B22025-07-295524P15289Espacenet
JP 2025522877 A2025-07-171041P15289Espacenet

1 to 10 of 83

See all 83 patents

Drugs1

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismAction
ATIDARSAGENE AUTOTEMCELCHEMBL4802262ARSA exogenous geneEXOGENOUS GENE

Source ChEMBL

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants794

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleARSA papersNewest fiscal year
R01DK067859Development of Assays for Newborn Screening and for Post-Screening Evaluation of Disease Severity142025
P30CA008748Cancer Center Support Grant62025
U24HG007346Center for Critical Assessment of Genome Interpretation42025
ZICMH002961Neurodevelopmental and Behavioral Phenotyping42025
P30ES010126UNC Center for Environmental Health and Susceptibility32025
R01NS017950Precursors of Stroke Incidence and Prognosis32025
T32GM007526Medical Genetics Research Fellowship Program32025
U54NS092090Developmental Synaptopathies Associated with TSC, PTEN, SHANK3 and SynGAP1 Pathogenic Variants32025
I01BX004823Defining high- and low-risk APOE ε4 haplotypes for Alzheimer’s disease22025
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions22025

1 to 10 of 794Source NIH's project files

See all 794 nih grants

Papers2,331

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Mammalian Expression and Mass Spectrometric Characterization of Highly Active Human Arylsulfatase A.Biotechnol J202642788422PubTator, text miningPubMed
Leukodystrophy in Tanzania: A Case Study Highlighting Diagnostic Dilemmas and Clinical Implications.Clin Case Rep202642787314PubTator, text miningPubMed
Evidence Regarding Metachromatic Leukodystrophy Newborn Screening.Pediatrics202642674587PubTator, text miningPubMed
Preliminary Data of the First Year of Newborn Screening for Metachromatic Leukodystrophy (MLD) in Lombardy.Int J Neonatal Screen202642496454PubTator, text miningPubMed
Ultra-rare variants in LAMA2 are risk factors for frontotemporal dementia and motor neuron disease.Hum Mol Genet202642165280PubTator, text miningPubMed
Expression of sulfate pathway genes in human neurodevelopment.J Neurogenet202642101182PubTator, text miningPubMed
A single nucleotide polymorphism that affects oligodendroglial lineage cells may augment the consequences of neurotoxicants.Neurotoxicology202642002102PubTator, text miningPubMed
Identification of tofersen PD-response biomarkers in VALOR clinical trial CSF via multiplexed quantitative proteomics.Cell Rep Med202641850233PubTator, text miningPubMed
Genomic modifiers of malignant and neurodevelopmental phenotypes in individuals with PTEN hamartoma tumor syndrome.NPJ Genom Med202641844650PubTator, text miningPubMed
Exploring genetic drivers of unexplained venous thromboembolism through whole-exome sequencing.Thromb Res202641831330PubTator, text miningPubMed

1 to 10 of 2,331

See all 2,331 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/410

GET https://conductscience.org/api/genes/v1/410/patents?page=2