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Gene · 4102

MAGEA3: MAGE family member A3

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MAGEA3: MAGE family member A3. Genes, record 4102. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4102

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Gene

Symbol
MAGEA3
HGNC
Name
MAGE family member A3
HGNC
NCBI Gene ID
4102
NCBI Gene
HGNC ID
HGNC:6801
HGNC
Ensembl
ENSG00000221867
NCBI Gene
Aliases
CT1.3, HIP8, HYPD, MAGE3, MGC14613
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P43357Melanoma-associated antigen 33146Ensembl, GeneID, HGNC

Source UniProt

Patents265

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
WO 2026209996 A12026-10-089P43357Espacenet
WO 2026210006 A12026-10-089P43357Espacenet
EP 4791437 A12026-08-1974P43357Espacenet
JP 2026094307 A2026-06-092P43357Espacenet
JP 2026004568 A2026-01-1453042P43357Espacenet
JP 2026004568 A2026-01-1453043P43357Espacenet
WO 2025264662 A12025-12-264P43357Espacenet
US 12485163 B22025-12-0287P43357Espacenet
JP 2025538524 A2025-11-285P43357Espacenet
WO 2025242815 A12025-11-27556P43357Espacenet

1 to 10 of 265

See all 265 patents

Drugs2

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
ASTUPROTIMUT-RCHEMBL2108705Melanoma-associated antigen 3 vaccine antigenVACCINE ANTIGENChEMBL
BIROPEPIMUT-SCHEMBL3990004Melanoma-associated antigen 3 vaccine antigenVACCINE ANTIGENChEMBL

Trials5

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT01437605ASTUPROTIMUT-RPHASE22019-12-20ClinicalTrials.gov
NCT00480025ASTUPROTIMUT-RPHASE32019-01-30ClinicalTrials.gov
NCT00455572ASTUPROTIMUT-RPHASE1ClinicalTrials.gov
NCT00257738ASTUPROTIMUT-RPHASE1ClinicalTrials.gov
NCT00090493ASTUPROTIMUT-RPHASE2/PHASE32013-06-24ClinicalTrials.gov

NIH grants1,412

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMAGEA3 papersNewest fiscal year
P30CA008748Cancer Center Support Grant382025
P30CA016672Cancer Center Support Grant252025
ZIABC010984Adoptive Cell Transfer Immunotherapy of Cancer252025
ZIABC010985Gene therapy of cancer202025
P30CA006973Regional Oncology Research Center162025
P30CA044579University of Virginia Cancer Center Support Grant162025
P30CA016056Roswell Park Cancer Center Support Grant142025
P30CA047904Cancer Center Support Grant122025
ZICBC010948DNA Sequencing and FACS Core Facilities122025
P50CA126752SPORE in Lymphoma102025

1 to 10 of 1,412Source NIH's project files

See all 1,412 nih grants

Papers3,353

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Investigation and validation of prognostic features associated with transient receptor potential channel genes in gastric cancer.PeerJ202642602890PubTator, text miningPubMed
iPSC-derived polyvalent vaccines as ontogenetically informed immunogens toward overcoming immune refractoriness in microsatellite-stable colorectal cancer: An emerging frontier in cancer immunotherapy.
Mol Immunol202642594762PubTator, text miningPubMed
AI-enabled virtual immunopeptidomics links quantitative neoantigen presentation to immunogenicity.bioRxiv202642146452PubTator, text miningPubMed
A Pan-Cancer Transcriptomic Signature for Conserved Molecular Programs Underlying Premalignant-Malignant Progression Across Common Carcinomas.Dent J (Basel)202642041682PubTator, text miningPubMed
Mechanisms of Polymer-Antigen Binding and Hydrolysis Inhibition: Molecular Dynamics Simulations and Experimental Measurements.Polymers (Basel)202641977530PubTator, text miningPubMed
Non-Invasive Urine-Based Diagnostic Technologies for Early Bladder Cancer.Biosensors (Basel)202641892063PubTator, text miningPubMed
Identification and evaluation of tumor pyroptosis-associated antigens for design a vaccine candidate against lung cancer.Sci Rep202641857073PubTator, text miningPubMed
Overcoming T cell tolerance to tumor self-antigens through catch-bond engineering.Science202641855322PubTator, text miningPubMed
Phase Ib multicenter study of anti-TIM-3 (S095018/Sym023) in combination with anti-PD-1 (Sym021) in patients with advanced/metastatic recurrent biliary tract cancer.J Immunother Cancer202641825935PubTator, text miningPubMed
Antibody screening for tumor and immune hotspot targets: The frontier of new methods and technologies.J Pharm Anal202641798069PubTator, text miningPubMed

1 to 10 of 3,353

See all 3,353 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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