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Gene · 4118

MAL: mal, T cell differentiation protein (MAL blood group)

12 sourcesgene-search-2026-11-11-0.2.0

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ConductScience Library. MAL: mal, T cell differentiation protein (MAL blood group). Genes, record 4118. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4118

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Gene

Symbol
MAL
HGNC
Name
mal, T cell differentiation protein (MAL blood group)
HGNC
NCBI Gene ID
4118
NCBI Gene
HGNC ID
HGNC:6817
HGNC
Ensembl
ENSG00000172005
NCBI Gene
Aliases
HLD28, MVP17, VIP17
NCBI Gene
Type
protein-coding
NCBI Gene

Proteins1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated in
P21145Myelin and lymphocyte protein1530Ensembl, GeneID, HGNC

Source UniProt

Patents52

Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1452459P21145Espacenet
JP 2025529142 A2025-09-042520P21145Espacenet
US 12371689 B22025-07-292520P21145Espacenet
JP 2025032204 A2025-03-1131152P21145Espacenet
EP 4461818 A22024-11-1331152P21145Espacenet
JP 2023058610 A2023-04-2531152P21145Espacenet
KR 1020220156460 A2022-11-251P21145Espacenet
US 11446398 B22022-09-2048850P21145Espacenet
US 11400116 B22022-08-022635P21145Espacenet
US 11401309 B22022-08-0229P21145Espacenet

1 to 10 of 52

See all 52 patents

Drugs0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

None in this release.

Trials0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

None in this release.

NIH grants1,714

NIH grants whose papers are about the gene, through NIH's grant-paper links.

GrantTitleMAL papersNewest fiscal year
P30CA008748Cancer Center Support Grant72025
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)72025
P30DK034854Integrated Epithelial and Muscosal Biology72025
P30CA016672Cancer Center Support Grant62025
P30DK043351Center for the Study of Inflammatory Bowel Disease at Massachusetts General Hospital52025
ZIACP010124Human papillomavirus (HPV) infection and cervical and anal cancers52025
P30CA021765Cancer Center Support Grant (CCSG)42025
P30CA068485Cancer Center Support Grant42025
P50CA159981Roswell Park Ovarian Cancer SPORE42025
P30CA016056Roswell Park Cancer Center Support Grant32025

1 to 10 of 1,714Source NIH's project files

See all 1,714 nih grants

Papers2,902

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
Twist1 Promotes Endothelial Phenotypic Transition and Unstable Plaque Phenotype During Atherosclerosis.Arterioscler Thromb Vasc Biol202642689320PubTator, text miningPubMed
ADRB2 modulates asbestos-induced pleural mesothelioma progression by influencing IL-17/NF-κB-related inflammatory signalling: An integrated network toxicology, multi-omics and experimental study.Chem Biol Interact202642595249PubTator, text miningPubMed
MyD88-Family Adaptors: Compartmentalised Signalling and Non-Immune Functions.Immunology202642552630PubTator, text miningPubMed
Bridging the gap between infection and detection: Biological, clinical, and health system contributors to diagnostic delay in HPV-associated cervical cancer.Crit Rev Oncol Hematol202642252068PubTator, text miningPubMed
Identification of potential biological targets in sepsis based on random forest and artificial neural network models.J Infect Dev Ctries202642112730PubTator, text miningPubMed
Rare anti-AnWj autoantibody in a 75-year-old male: Case report and review of the literature.Transfus Apher Sci202642085873PubTator, text miningPubMed
MAL/SPP1 axis drives tumor proliferation and immune evasion via JAK2/STAT3 and MHC class Ib in breast cancer.Int Immunopharmacol202642061141PubTator, text miningPubMed
The Overexpression of Myelin and Lymphocyte Protein (MAL) Downregulates MUC1 and Enhances Cisplatin Sensitivity in Non-Small Cell Lung Cancer Cells.J Cancer202642038033PubTator, text miningPubMed
Time-dependent cell adhesion to lectin-coated surfaces as a predictor of flow-based separation efficiency.Int J Biol Macromol202641999814PubTator, text miningPubMed
Infrared Photobiomodulation Modulates PpIX Production After Topical Methyl Aminolevulinate in Normal Human Skin: An Exploratory Study.J Biophotonics202641891138PubTator, text miningPubMed

1 to 10 of 2,902

See all 2,902 papers

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

For software

Read this gene from software.

The record and each of its lists are JSON, twenty rows a page. No key.

GET https://conductscience.org/api/genes/v1/4118

GET https://conductscience.org/api/genes/v1/4118/patents?page=2