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MAOA: monoamine oxidase A

1 protein, 52 patents, 17 drugs, 17 trials, 3,380 NIH grants and 7,924 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMAOAHGNC
Namemonoamine oxidase AHGNC
NCBI Gene ID4128NCBI Gene
HGNC IDHGNC:6833HGNC
EnsemblENSG00000189221NCBI Gene
AliasesBRNRS, MAO-ANCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P21397Amine oxidase [flavin-containing] A5274Ensembl, GeneID, HGNCUniProt

Patents 52

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454053P21397Espacenet
EP 4650780 A22025-11-196563P21397Espacenet
JP 2025529142 A2025-09-042534P21397Espacenet
US 12371689 B22025-07-292534P21397Espacenet
JP 2025517970 A2025-06-126563P21397Espacenet
JP 2023505507 A2023-02-094P21397Espacenet
US 11446398 B22022-09-2052843P21397Espacenet
JP 2022524081 A2022-04-27155814P21397Espacenet
US 11279916 B22022-03-2220P21397Espacenet
US 11078247 B22021-08-036524P21397Espacenet

Drugs 17

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
INDANTADOLCHEMBL3707400Monoamine oxidase A inhibitorINHIBITORChEMBL
IPRONIAZIDCHEMBL92401Monoamine oxidase inhibitorINHIBITORChEMBL
ISOCARBOXAZIDCHEMBL1201168Monoamine oxidase inhibitorINHIBITORChEMBL
MEBANAZINECHEMBL1909283Monoamine oxidase inhibitorINHIBITORChEMBL
MINAPRINECHEMBL278819Monoamine oxidase A inhibitorINHIBITORChEMBL
MINAPRINE HYDROCHLORIDECHEMBL1364551Monoamine oxidase A inhibitorINHIBITORChEMBL
MOCLOBEMIDECHEMBL86304Monoamine oxidase A inhibitorINHIBITORChEMBL
NIALAMIDECHEMBL1256841Monoamine oxidase inhibitorINHIBITORChEMBL
PARGYLINECHEMBL673Monoamine oxidase inhibitorINHIBITORChEMBL
PARGYLINE HYDROCHLORIDECHEMBL1200425Monoamine oxidase inhibitorINHIBITORChEMBL

Trials 17

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT03505528PHENELZINE SULFATEPHASE1ClinicalTrials.gov
NCT02717884TRANYLCYPROMINEPHASE1/PHASE2ClinicalTrials.gov
NCT02273102TRANYLCYPROMINEPHASE1ClinicalTrials.gov
NCT02261779TRANYLCYPROMINEPHASE1/PHASE2ClinicalTrials.gov
NCT02217709PHENELZINE SULFATEPHASE2ClinicalTrials.gov
NCT01944657PHENELZINEClinicalTrials.gov
NCT01944657TRANYLCYPROMINEClinicalTrials.gov
NCT01926626MOCLOBEMIDEPHASE22015-07-29ClinicalTrials.gov
NCT01896349TRANYLCYPROMINEClinicalTrials.gov
NCT01253642PHENELZINE SULFATEPHASE22017-12-11ClinicalTrials.gov

NIH grants 3380

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
ZIAAA000301Integrative genetics of behavior with high throughput technologies372,025NIH's project files
P51OD011107California National Primate Research Center152,025NIH's project files
ZIAAA000550Neurobiology of Drug Reward and Addiction142,025NIH's project files
ZIANS003034Biomarkers of Catecholaminergic Neurodegeneration132,025NIH's project files
R01MH104603Deciphering gene-environment interactions in pathological reactive aggression122,025NIH's project files
U10AA008401Collaborative Study on the Genetics of Alcoholism (COGA).102,025NIH's project files
T32MH020030ResearchTraining: Psychiatric and Statistical Genetics82,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award72,025NIH's project files
ZIAAA000281Genetic influences on alcohol use disorder in Native Americans72,025NIH's project files
P30CA014089University of Southern California Norris Comprehensive Cancer Center Support Grant (CCSG)62,025NIH's project files

Papers 7924

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42814888PubTator, text miningPubMed
42802518PubTator, text miningPubMed
42796609PubTator, text miningPubMed
42794540PubTator, text miningPubMed
42788140PubTator, text miningPubMed
42786817PubTator, text miningPubMed
42776425PubTator, text miningPubMed
42768110PubTator, text miningPubMed
42736669PubTator, text miningPubMed
42730070PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license