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MAOB: monoamine oxidase B

1 protein, 39 patents, 19 drugs, 99 trials, 2,425 NIH grants and 7,726 papers.

Gene 6

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMAOBHGNC
Namemonoamine oxidase BHGNC
NCBI Gene ID4129NCBI Gene
HGNC IDHGNC:6834HGNC
EnsemblENSG00000069535NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P27338Amine oxidase [flavin-containing] B52057Ensembl, GeneID, HGNCUniProt

Patents 39

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
JP 2026004568 A2026-01-1454055P27338Espacenet
EP 4650780 A22025-11-199998P27338Espacenet
EP 4641201 A22025-10-2910273P27338Espacenet
JP 2025529142 A2025-09-042535P27338Espacenet
US 12371689 B22025-07-292535P27338Espacenet
JP 2025517969 A2025-06-1210273P27338Espacenet
JP 2025517970 A2025-06-129998P27338Espacenet
US 12083116 B22024-09-106P27338Espacenet
JP 2023505507 A2023-02-096P27338Espacenet
US 11446398 B22022-09-2052845P27338Espacenet

Drugs 19

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource
IPRONIAZIDCHEMBL92401Monoamine oxidase inhibitorINHIBITORChEMBL
ISOCARBOXAZIDCHEMBL1201168Monoamine oxidase inhibitorINHIBITORChEMBL
MEBANAZINECHEMBL1909283Monoamine oxidase inhibitorINHIBITORChEMBL
NIALAMIDECHEMBL1256841Monoamine oxidase inhibitorINHIBITORChEMBL
PARGYLINECHEMBL673Monoamine oxidase inhibitorINHIBITORChEMBL
PARGYLINE HYDROCHLORIDECHEMBL1200425Monoamine oxidase inhibitorINHIBITORChEMBL
PHENELZINECHEMBL1089Monoamine oxidase inhibitorINHIBITORChEMBL
PHENELZINE SULFATECHEMBL1200895Monoamine oxidase inhibitorINHIBITORChEMBL
PHENOXYPROPAZINECHEMBL1909286Monoamine oxidase inhibitorINHIBITORChEMBL
RALFINAMIDECHEMBL2107771Monoamine oxidase B inhibitorINHIBITORChEMBL

Trials 99

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource
NCT07077187RASAGILINEPHASE4ClinicalTrials.gov
NCT06798519RASAGILINEPHASE1ClinicalTrials.gov
NCT05312632SAFINAMIDE MESYLATEPHASE42024-09-23ClinicalTrials.gov
NCT04870372SELEGILINEPHASE4ClinicalTrials.gov
NCT04586543SELEGILINEPHASE2ClinicalTrials.gov
NCT03968744SAFINAMIDEPHASE4ClinicalTrials.gov
NCT03944785SAFINAMIDE2021-02-18ClinicalTrials.gov
NCT03881371SAFINAMIDEPHASE32024-03-20ClinicalTrials.gov
NCT03843944SAFINAMIDEPHASE4ClinicalTrials.gov
NCT03841604SAFINAMIDEPHASE42023-05-22ClinicalTrials.gov

NIH grants 2425

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
P30ES007033University of Washington Interdisciplinary Center for Exposures, Diseases, Genomics & Environment92,025NIH's project files
P20GM109025Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - Resubmission82,025NIH's project files
ZIANS003034Biomarkers of Catecholaminergic Neurodegeneration72,025NIH's project files
ZIAAA000301Integrative genetics of behavior with high throughput technologies62,025NIH's project files
P30AG062421Massachusetts Alzheimer's Disease Research Center (MADRC)52,025NIH's project files
P51OD011106Wisconsin National Primate Research Center Support52,025NIH's project files
R01ES010563Mechanisms of Manganese Neurotoxicity52,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award52,025NIH's project files
P01AG019724Frontotemporal Dementia: Genes, Images, and Emotions42,025NIH's project files
P01AG036694Impact of Amyloid and Tau on the Aging Brain: The Harvard Aging Brain Study42,025NIH's project files

Papers 7726

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42818885PubTator, text miningPubMed
42814888PubTator, text miningPubMed
42800646PubTator, text miningPubMed
42796609PubTator, text miningPubMed
42788140PubTator, text miningPubMed
42779508PubTator, text miningPubMed
42776425PubTator, text miningPubMed
42774697PubTator, text miningPubMed
42762305PubTator, text miningPubMed
42758107PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license