Gene · 4134
MAP4: microtubule associated protein 4
12 sourcesgene-search-2026-11-11-0.2.0
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ConductScience Library. MAP4: microtubule associated protein 4. Genes, record 4134. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4134
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Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P27816 | Microtubule-associated protein 4 | 1,152 | 0 | Ensembl, GeneID, HGNC |
Source UniProt
Patents28
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 53571 | P27816 | Espacenet |
| EP 4650780 A2 | 2025-11-19 | 7756 | P27816 | Espacenet |
| JP 2025517970 A | 2025-06-12 | 7756 | P27816 | Espacenet |
| EP 4565198 A2 | 2025-06-11 | 3 | P27816 | Espacenet |
| JP 2023064789 A | 2023-05-12 | 94 | P27816 | Espacenet |
| WO 2023074712 A | 2023-05-04 | 40 | P27816 | Espacenet |
| JP 2022550377 A | 2022-12-01 | 27 | P27816 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 51500 | P27816 | Espacenet |
| US 11408034 B2 | 2022-08-09 | 500 | P27816 | Espacenet |
| KR 1020220069032 A | 2022-05-26 | 27 | P27816 | Espacenet |
1 to 10 of 28
See all 28 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants1,258
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MAP4 papers | Newest fiscal year |
|---|---|---|---|
| R01HL086694 | From GWAS loci to blood pressure genes, variants & mechanisms - Renewal | 4 | 2025 |
| R35GM134955 | Phosphoinositide Signaling in Cytosol and Nucleus | 4 | 2025 |
| P30CA016042 | Cancer Center Support Grant | 3 | 2025 |
| P30DK020572 | Michigan Diabetes Research Center (MDRC) | 3 | 2025 |
| P30DK063491 | Diabetes Research Center (DRC) | 3 | 2025 |
| R01AG011085 | Ubiquitin‐mediated proteolysis and cell cycle control | 3 | 2025 |
| R01GM074207 | Analysis of Centrosome Dynamics | 3 | 2025 |
| R35GM133688 | Defining microtubule cytoskeleton regulatory pathways in development and disease | 3 | 2025 |
| P2CHD047873 | Center for Demography and Ecology | 2 | 2025 |
| P2CHD050924 | Carolina Population Center | 2 | 2025 |
1 to 10 of 1,258Source NIH's project files
See all 1,258 nih grantsPapers1,378
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| Integrated Transcriptomic Analysis Identifies Potential Biomarkers in Castration-Resistant Prostate Cancer. | World J Oncol | 2026 | 42490773 | PubTator, text mining | PubMed |
| HMGA2 Mediates Uterine Fibroid Progression via MAP4-Dependent Regulation of ECM and EMT. | Tohoku J Exp Med | 2026 | 42342381 | PubTator, text mining | PubMed |
| AUF1 modulates cellular senescence in auditory hair cells by regulating the transcription and alternative splicing of immune response genes. | Mol Biol Rep | 2026 | 42189329 | PubTator, text mining | PubMed |
| Discovering proteo-transcriptomic networks via biologically informed heterogeneous graph learning. | Nucleic Acids Res | 2026 | 42059203 | PubTator, text mining | PubMed |
| Architects of the Developing Brain: Cytoskeleton-Organizing Molecules in Neurodevelopmental Disorders. | Cells | 2026 | 41892327 | PubTator, text mining | PubMed |
| Subcellular calcium dynamics and organelle perturbations in resistosome-mediated cell death. | Proc Natl Acad Sci U S A | 2026 | 41849389 | PubTator, text mining | PubMed |
| Microtubule-Associated Protein 4 Overexpression Correlates with Early Recurrence in Hepatitis B Virus-Associated Hepatocellular Carcinoma Patients Following Curative Hepatic Resection. | J Hepatocell Carcinoma | 2026 | 41847218 | PubTator, text mining | PubMed |
| FBXW7 Targets the SPT6-ΔNp63 Axis for Degradation to Inhibit Esophageal Tumorigenesis Induced by 4-Nitroquinoline N-Oxide. | MedComm (2020) | 2026 | 41799933 | PubTator, text mining | PubMed |
| Single-Cell Multi-Omics Profiling of Human Septal Myectomy Tissue: Toward Precision Medicine in Obstructive Hypertrophic Cardiomyopathy. | J Pers Med | 2026 | 41745380 | PubTator, text mining | PubMed |
| Prognostic model based on stem cells and oxidative stress related genes for ovarian cancer. | Medicine (Baltimore) | 2026 | 41731838 | PubTator, text mining | PubMed |
1 to 10 of 1,378
See all 1,378 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
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The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4134
GET https://conductscience.org/api/genes/v1/4134/patents?page=2