Gene · 4145
MATK: megakaryocyte-associated tyrosine kinase
12 sourcesgene-search-2026-11-11-0.2.0
Cite this record
ConductScience Library. MATK: megakaryocyte-associated tyrosine kinase. Genes, record 4145. Release gene-search-2026-11-11-0.2.0, 11 Nov 2026. https://conductscience.org/library/genes/4145
On this page
Gene
Proteins1
Reviewed human proteins whose Swiss-Prot entry states the gene.
| UniProt entry | Protein | Length | Structures | Gene stated in |
|---|---|---|---|---|
| P42679 | Megakaryocyte-associated tyrosine-protein kinase | 507 | 3 | Ensembl, GeneID, HGNC |
Source UniProt
Patents21
Patents whose sequence listing contains this protein's exact sequence. A patent can list a sequence without claiming it.
| Publication | Published | SEQ ID NO | Protein | Source |
|---|---|---|---|---|
| JP 2026004568 A | 2026-01-14 | 52981 | P42679 | Espacenet |
| EP 4641201 A2 | 2025-10-29 | 4134 | P42679 | Espacenet |
| EP 4641202 A2 | 2025-10-29 | 4839 | P42679 | Espacenet |
| JP 2025517969 A | 2025-06-12 | 4134 | P42679 | Espacenet |
| KR 1020250017231 A | 2025-02-04 | 4839 | P42679 | Espacenet |
| US 11446398 B2 | 2022-09-20 | 49941 | P42679 | Espacenet |
| JP 2022524081 A | 2022-04-27 | 152912 | P42679 | Espacenet |
| JP 2019054813 A | 2019-04-11 | 233416 | P42679 | Espacenet |
| JP 2017121241 A | 2017-07-13 | 233416 | P42679 | Espacenet |
| JP 2015516143 A | 2015-06-08 | 233416 | P42679 | Espacenet |
1 to 10 of 21
See all 21 patentsDrugs0
Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.
None in this release.
Trials0
Trials of those drugs. A trial joins the gene only through a drug that acts on it.
None in this release.
NIH grants788
NIH grants whose papers are about the gene, through NIH's grant-paper links.
| Grant | Title | MATK papers | Newest fiscal year |
|---|---|---|---|
| P30CA016672 | Cancer Center Support Grant | 14 | 2025 |
| P30CA008748 | Cancer Center Support Grant | 3 | 2025 |
| P30CA042014 | Cancer Center Support Grant | 3 | 2025 |
| R35GM130389 | Lessons Learned from PKA: Assembly of Dynamic Macromolecular Switches | 3 | 2025 |
| P01AI091580 | Defining the Unique Properties of the Distinct Signaling Machinery Used by the TCR | 2 | 2025 |
| P01CA120964 | Molecular Pathogenesis of the Hamartoma Syndromes | 2 | 2025 |
| P20GM103430 | Rhode Island IDeA Network of Biomedical Research Excellence | 2 | 2025 |
| P20GM103434 | West Virginia IDeA Network of Biomedical Research Excellence (WV-INBRE) | 2 | 2025 |
| P20GM121327 | University of Kentucky Center for Cancer Metabolism | 2 | 2025 |
| P30CA006973 | Regional Oncology Research Center | 2 | 2025 |
1 to 10 of 788Source NIH's project files
See all 788 nih grantsPapers2,664
Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.
| Title | Journal | Year | PMID | Found by | Source |
|---|---|---|---|---|---|
| New discoveries of Lanonia (Arecaceae) from northern Vietnam and southwestern China. | PhytoKeys | 2026 | 42798846 | PubTator, text mining | PubMed |
| DNA barcoding to delineate species boundaries and assess genetic divergence in halophytes of the United Arab Emirates. | J Genet Eng Biotechnol | 2026 | 42749397 | PubTator, text mining | PubMed |
| Fatty Acid-Binding Protein 5 Potentially Regulates the Proliferation and Metastasis of Uveal Melanoma Cells Through the PI3K/AKT/mTOR Signaling Pathway. | CNS Neurosci Ther | 2026 | 42695184 | PubTator, text mining | PubMed |
| Diagnostic Value of Oxidative Stress-Related Features Mined by WGCNA and Machine Learning in Respiratory Syncytial Virus Infection. | Adv Biol (Weinh) | 2026 | 42500833 | PubTator, text mining | PubMed |
| Adenosine Pathway-Based Prognostic Signature for Predicting Clinical Outcomes and Immune Microenvironment Characteristics in Epithelial Ovarian Cancer. | J Clin Pract Res | 2026 | 42416131 | PubTator, text mining | PubMed |
| Anatomy and the chloroplast genome of Bischofia plants reveal important phylogenetic relationship and the genetic diversity in phyllanthaceae. | Sci Rep | 2026 | 42128939 | PubTator, text mining | PubMed |
| Complete Chloroplast Genomes of Ranunculus arvensis and Ranunculus laetus: Comparative Analysis and Phylogenetic Insights. | Ecol Evol | 2026 | 42078674 | PubTator, text mining | PubMed |
| Microbial Hyaluronidases: From Obscure Virulence Factors to Promising Therapeutic Targets. | Biomolecules | 2026 | 42072637 | PubTator, text mining | PubMed |
| Integration of 117 machine learning algorithms and single-cell transcriptomics identifies macrophage polarization and ER stress signatures for cancer prognosis and precision therapy. | Discov Oncol | 2026 | 42062606 | PubTator, text mining | PubMed |
| Single-cell multi-omics sequencing reveals cell-specific transcriptomic and chromatin accessibility profiles in gut microbiome metabolite butyrate-produced pain modulation. | Int J Oral Sci | 2026 | 41997906 | PubTator, text mining | PubMed |
1 to 10 of 2,664
See all 2,664 papersSources 12
- ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
- ChEMBL, through Open TargetsCC BY-SA 3.0
- ClinicalTrials.govNo license stated
- EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
- GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
- HGNCCC0
- NCBI GenePublic domain (US government)
- NIH's project files and grant-paper linksPublic domain
- Open TargetsCC0 1.0
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0
Each source's terms
- ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
- ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- ClinicalTrials.govnone stated
- EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
- GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
- HGNCCC0: https://www.genenames.org/about/license/
- NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
- NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
- Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
- PubMedNLM's terms
- PubTator 3Public domain
- UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license
ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.
For software
Read this gene from software.
The record and each of its lists are JSON, twenty rows a page. No key.
GET https://conductscience.org/api/genes/v1/4145
GET https://conductscience.org/api/genes/v1/4145/patents?page=2