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MBL2: mannose binding lectin 2

1 protein, 207 patents, 0 drugs, 0 trials, 3,425 NIH grants and 7,731 papers.

Gene 7

Its symbol and name are HGNC's, unless HGNC and NCBI Gene contradict each other.

FieldValueSource
SymbolMBL2HGNC
Namemannose binding lectin 2HGNC
NCBI Gene ID4153NCBI Gene
HGNC IDHGNC:6922HGNC
EnsemblENSG00000165471NCBI Gene
AliasesCOLEC1, HSMBPC, MBL, MBL2D, MBP, MBP-C, MBP1, MBPD, NIZP1NCBI Gene
Typeprotein-codingNCBI Gene

Proteins 1

Reviewed human proteins whose Swiss-Prot entry states the gene.

UniProt entryProteinLengthStructuresGene stated inSource
P11226Mannose-binding protein C2481Ensembl, GeneID, HGNCUniProt

Patents 207

Patents whose sequence listing holds the protein exactly: the same sequence, by SHA-256, length and CRC-64. A sequence a patent lists is not always one it claims.

PublicationPublishedSEQ ID NOProteinSource
EP 4775273 A22026-07-1521P11226Espacenet
JP 2026062897 A2026-04-1021P11226Espacenet
JP 2026004568 A2026-01-1452523P11226Espacenet
WO 2025262255 A12025-12-263P11226Espacenet
EP 4650780 A22025-11-199410P11226Espacenet
JP 2025147176 A2025-10-068406P11226Espacenet
JP 2025529142 A2025-09-046988P11226Espacenet
US 12371689 B22025-07-296988P11226Espacenet
JP 2025108730 A2025-07-2321P11226Espacenet
JP 2025517970 A2025-06-129410P11226Espacenet

Drugs 0

Drugs a ChEMBL mechanism record says act on the gene's protein, through Open Targets.

DrugChEMBL IDMechanismActionSource

Trials 0

Trials of those drugs. A trial joins the gene only through a drug that acts on it.

TrialDrugPhaseResults first postedSource

NIH grants 3425

NIH projects whose papers are about the gene, through NIH's grant-paper links.

ProjectTitleIts papers about the geneNewest fiscal yearSource
R01AR051749Complement in the Pathogenesis of Autoimmune Arthritis152,025NIH's project files
R01DK078244Molecular Basis of Pathogenicity of IgA1-containing Immune Complexes142,025NIH's project files
P30CA008748Cancer Center Support Grant122,025NIH's project files
R01DK076690Complement-mediated injury of the kidney: New mechanisms and novel therapies102,025NIH's project files
P20GM103418Kansas IDeA Network of Biomedical Research Excellence 582,025NIH's project files
UM1AI144462Consortium for HIV/AIDS Vaccine Development82,025NIH's project files
P51OD011106Wisconsin National Primate Research Center Support72,025NIH's project files
UL1TR001863Yale Clinical and Translational Science Award72,025NIH's project files
ZIAHD002400The Role Of Subclinical Infection And Cytokines In Preterm Parturition72,025NIH's project files
ZIAHL006223The role of the intracellular complement system - the complosome - in Th1 biology72,025NIH's project files

Papers 7731

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

PMIDFound bySource
42746023PubTator, text miningPubMed
42711363PubTator, text miningPubMed
42654216PubTator, text miningPubMed
42650782PubTator, text miningPubMed
42620364PubTator, text miningPubMed
42606632PubTator, text miningPubMed
42546778PubTator, text miningPubMed
42498041PubTator, text miningPubMed
42461968PubTator, text miningPubMed
42456427PubTator, text miningPubMed

The same record as JSON

Release gene-search-2026-11-11-0.1.0

ClinicalTrials.gov's posted results, through CTTI's AACT: ClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299 ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

ChEMBL, through Open Targets: CC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

ClinicalTrials.gov: none stated ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

EMBL-EBI's patent proteins: EMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use

GenBank's patent files: GenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/

HGNC: CC0: https://www.genenames.org/about/license/

NCBI Gene: None named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/

NIH's project files and grant-paper links: Public domain (NIH RePORTER)

Open Targets: CC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence

PubTator 3: Public domain

UniProt: CC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license