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Gene · 4158

Papers1,357

Newest first. Swiss-Prot's references are curated; PubTator's text mining finds papers that name the gene, not always ones about it.

TitleJournalYearPMIDFound bySource
MRAP2 modifies the signaling and oligomerization state of the melanocortin-4 receptor.Nat Commun202540998819PubTator, text miningPubMed
Inherited, Non-CAH Primary Adrenal Insufficiency in Children: A Genetic and Clinical Profile from a Tertiary Care Centre.Indian J Endocrinol Metab202540917321PubTator, text miningPubMed
First-Degree Family History of Diabetes Is Associated With the Presence of Depressive Symptoms Independent of Lifestyle Risk Factors and Cardiometabolic Risk Factors.J Diabetes202540820550PubTator, text miningPubMed
Uniparental disomy leads to a novel cause of MC2R-related familial glucocorticoid deficiency type 1.Eur J Endocrinol202540729435PubTator, text miningPubMed
Case report and literature review: novel TXNRD2 compound heterozygous variants in familial glucocorticoid deficiency type 5.Front Pediatr202540726908PubTator, text miningPubMed
Bimodal Genomic Approach Predicting Semaphorin 7A (SEMA7A) as Prognostic Biomarker in Adrenocortical Carcinoma.Cancers (Basel)202540647379PubTator, text miningPubMed
[Molecular genetics in pediatric endocrinology: 35 years of research].Probl Endokrinol (Mosk)202540411325PubTator, text miningPubMed
Structural basis for the constitutive activity of the melanocortin receptor family.Structure202540157361PubTator, text miningPubMed
Melanocortin 4 Receptor-Dependent Mechanism of ACTH in Preventing Anxiety-Like Behaviors and Normalizing Astrocyte Proteins after Early Life Seizures.eNeuro202540015967PubTator, text miningPubMed
Antenatal diagnosis and early postnatal management of a neonate with type 1 familial glucocorticoid deficiency.BMJ Case Rep202540000035PubTator, text miningPubMed
Adrenocorticotropic hormone and its receptor as a novel testicular system involves in the development of spermatogenesis.Life Sci202539978588PubTator, text miningPubMed
Familial glucocorticoid deficiency: genetic insights and treatment strategies in resource-limited settings.BMJ Case Rep202539956565PubTator, text miningPubMed
Understanding the biochemistry of hormones - message in a bottle.Essays Biochem202539916408PubTator, text miningPubMed
Genetics of Primary Adrenal Insufficiency Beyond CAH in Saudi Arabian Population.Mol Genet Genomic Med202539853971PubTator, text miningPubMed
Clinical and Genetic Mechanisms in Patients with <italic>MC2R</italic> Deficiency Presenting with Early Puberty.Horm Res Paediatr202539496238PubTator, text miningPubMed
The melanocortin receptor genes are linked to and associated with the risk of polycystic ovary syndrome in Italian families.J Ovarian Res202439633478PubTator, text miningPubMed
New Trends in Treating Cushing's Disease.touchREV Endocrinol202439526050PubTator, text miningPubMed
NGT: Generative AI with Synthesizability Guarantees Discovers MC2R Inhibitors from a Tera-Scale Virtual Screen.J Med Chem202439471377PubTator, text miningPubMed
Aberrant hormone receptors regulate a wide spectrum of endocrine tumors.Lancet Diabetes Endocrinol202439326429PubTator, text miningPubMed
Recommended Tool Compounds for the Melanocortin Receptor (MCR) G Protein-Coupled Receptors (GPCRs).ACS Pharmacol Transl Sci202439296259PubTator, text miningPubMed

gene-search-2026-11-11-0.2.0

Sources 12

  • ClinicalTrials.gov's posted results, through CTTI's AACTFreely available. Acknowledgement requested
  • ChEMBL, through Open TargetsCC BY-SA 3.0
  • ClinicalTrials.govNo license stated
  • EMBL-EBI's patent proteinsNo added restrictions. Attribution expected
  • GenBank's patent filesNo restrictions from NCBI. Submitters may hold rights
  • HGNCCC0
  • NCBI GenePublic domain (US government)
  • NIH's project files and grant-paper linksPublic domain
  • Open TargetsCC0 1.0
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0
Each source's terms
  • ClinicalTrials.gov's posted results, through CTTI's AACTClinicalTrials.gov data via Aggregate Analysis of ClinicalTrials.gov (AACT), CTTI. CTTI makes its materials freely available and requests acknowledgement. https://aact.ctti-clinicaltrials.org/documentation/299
  • ChEMBL, through Open TargetsCC BY-SA 3.0, for the parts from ChEMBL. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • ClinicalTrials.govnone stated
  • EMBL-EBI's patent proteinsEMBL-EBI's patent protein files from the EPO, JPO, KIPO and USPTO. EMBL-EBI: "EMBL-EBI itself places no additional restrictions on the use or redistribution of the data available via its Data Resources and Tools other than those provided by the original data owners" and "EMBL-EBI expects attribution (e.g. in publications, services or products) for the use of any of its Data Resources and Tools." Read on 11 Nov 2026 at https://www.ebi.ac.uk/about/terms-of-use
  • GenBank's patent filesGenBank's patent files. NCBI: "NCBI places no restrictions on the use or distribution of the GenBank data. However, some submitters may claim patent, copyright, or other intellectual property rights in all or a portion of the data they have submitted." Read on 11 Nov 2026 at https://www.ncbi.nlm.nih.gov/genbank/about/
  • HGNCCC0: https://www.genenames.org/about/license/
  • NCBI GeneNone named for the file. NCBI says information created by or for the US government on its site is in the public domain, and asks that NLM be acknowledged: https://www.ncbi.nlm.nih.gov/home/about/policies/
  • NIH's project files and grant-paper linksPublic domain (NIH RePORTER)
  • Open TargetsCC0 1.0. Open Targets asks that users cite its latest paper: Buniello et al. 2025, Open Targets Platform: facilitating therapeutic hypotheses building in drug discovery, Nucleic Acids Research 53(D1):D1467, PMID 39657122. Read on 8 Nov 2026 at https://platform-docs.opentargets.org/licence
  • PubMedNLM's terms
  • PubTator 3Public domain
  • UniProtCC BY 4.0. UniProt's licence file: "All databases and documents in the UniProt FTP directory may be copied and redistributed freely, without advance permission, provided that this copyright statement is reproduced with each copy." UniProt asks that users cite its latest paper: The UniProt Consortium, UniProt: the Universal Protein Knowledgebase in 2025, Nucleic Acids Research 53:D609-D617, https://doi.org/10.1093/nar/gkae1010. Read on 9 Nov 2026 at https://www.uniprot.org/help/license

ClinicalTrials.gov's data carry an international copyright outside the United States: https://clinicaltrials.gov/about-site/terms-conditions.

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